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. 1982 Nov;39(4):349–354. doi: 10.1136/oem.39.4.349

Asbestos bodies in the lung: Southampton (UK) and Wellington (New Zealand).

R H Steele, K J Thomson
PMCID: PMC1009065  PMID: 6753915

Abstract

Two series of surgically removed and unselected necropsy lungs were examined for asbestos bodies. In the series from Southampton (UK) 30-mu sections were used and in the Wellington (New Zealand) series a modified Gold's digestion method was used for all cases, together with 30-mu sections for some. A further series of Southampton lungs was assessed by Gold's method six years after the initial study. The 30-mu section technique found asbestos bodies in 13% of Southampton men and none in women: the corresponding Wellington figures were 8% for men and nil for women. In Wellington the more sensitive digestion method found asbestos bodies in 78% of men and 63% of women. In Southampton the investigation by Gold's method found asbestos bodies in 83% of men and 74% of women. No statistically significant association was found between the number of asbestos bodies and the various types of lung carcinoma. The prevalence of asbestos in lungs removed between 1956 and 1965 did not differ significantly from its prevalence in those removed in the late 1970's. There was no significant increase in asbestos after the age of 20.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Auerbach O., Hammond E. C., Selikoff I. J., Parks V. R., Kaslow H. D., Garfinkel L. Asbestos bodies in lung parenchyma in relation to ingestion and inhalation of mineral fibers. Environ Res. 1977 Oct;14(2):286–304. doi: 10.1016/0013-9351(77)90038-x. [DOI] [PubMed] [Google Scholar]
  2. Bhagavan B. S., Koss L. G. Secular trends in prevalence and concentration of pulmonary asbestos bodies--1940 to 1972. A necropsy study. Arch Pathol Lab Med. 1976 Oct;100(10):539–541. [PubMed] [Google Scholar]
  3. Breedin P. H., Buss D. H. Ferruginous (asbestos) bodies in the lungs of rural dwellers, urban dwellers, and patients with pulmonary neoplasms. South Med J. 1976 Apr;69(4):401–404. doi: 10.1097/00007611-197604000-00007. [DOI] [PubMed] [Google Scholar]
  4. Churg A. M., Warnock M. L. Analysis of the cores of ferruginous (asbestos) bodies from the general population. III. Patients with environmental exposure. Lab Invest. 1979 May;40(5):622–626. [PubMed] [Google Scholar]
  5. Churg A. M., Warnock M. L. Asbestos and other ferruginous bodies: their formation and clinical significance. Am J Pathol. 1981 Mar;102(3):447–456. [PMC free article] [PubMed] [Google Scholar]
  6. Churg A., Warnock M. L. Correlation of quantitative asbestos body counts and occupation in urban patients. Arch Pathol Lab Med. 1977 Dec;101(12):629–634. [PubMed] [Google Scholar]
  7. DOLL R. Mortality from lung cancer in asbestos workers. Br J Ind Med. 1955 Apr;12(2):81–86. doi: 10.1136/oem.12.2.81. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Dicke T. E., Naylor B. Prevalence of "asbestos" bodies in human lungs at necropsy. Dis Chest. 1969 Aug;56(2):122–125. doi: 10.1378/chest.56.2.122. [DOI] [PubMed] [Google Scholar]
  9. Doniach I., Swettenham K. V., Hathorn M. K. Prevalence of asbestos bodies in a necropsy series in East London: association with disease, occupation, and domiciliary address. Br J Ind Med. 1975 Feb;32(1):16–30. doi: 10.1136/oem.32.1.16. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Francis D., Jussuf A., Mortensen T., Sikjaer B., Viskum K. Hyaline pleural plaques and asbestos bodies in 198 randomized autopsies. Scand J Respir Dis. 1977 Aug;58(4):193–196. [PubMed] [Google Scholar]
  11. Gordon P., Rosen P. P., Savino A. The ferruginous body content of lungs at autopsy in Boston 1928-1932. Acta Cytol. 1976 Nov-Dec;20(6):521–524. [PubMed] [Google Scholar]
  12. Hasan F. M., Nash G., Kazemi H. Asbestos exposure and related neoplasia. The 28 year experience of a major urban hospital. Am J Med. 1978 Oct;65(4):649–654. doi: 10.1016/0002-9343(78)90853-7. [DOI] [PubMed] [Google Scholar]
  13. Hillerdal G., Nõu E. Occupation and bronchial carcinoma. Scand J Respir Dis. 1979 Apr;60(2):76–82. [PubMed] [Google Scholar]
  14. Huuskonen M. S. Clinical features, mortality and survival of patients with asbestosis. Scand J Work Environ Health. 1978 Dec;4(4):265–274. doi: 10.5271/sjweh.2699. [DOI] [PubMed] [Google Scholar]
  15. Hägerstrand I., Seifert B. Asbestos bodies and pleural plaques in human lungs at necropsy. Acta Pathol Microbiol Scand A. 1973 Jul;81(4):457–460. doi: 10.1111/j.1699-0463.1973.tb00492.x. [DOI] [PubMed] [Google Scholar]
  16. Meurman L. O., Kiviluoto R., Hakama M. Mortality and morbidity among the working population of anthophyllite asbestos miners in Finland. Br J Ind Med. 1974 Apr;31(2):105–112. doi: 10.1136/oem.31.2.105. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Polliack A., Sacks M. I. Prevalence of asbestos bodies in basal lung smears. Isr J Med Sci. 1968 Mar-Apr;4(2):223–226. [PubMed] [Google Scholar]
  18. Selikoff I. J., Hammond E. C. Asbestos and smoking. JAMA. 1979 Aug 3;242(5):458–459. [PubMed] [Google Scholar]
  19. Vincent R. G., Pickren J. W., Lane W. W., Bross I., Takita H., Houten L., Gutierrez A. C., Rzepka T. The changing histopathology of lung cancer: a review of 1682 cases. Cancer. 1977 Apr;39(4):1647–1655. doi: 10.1002/1097-0142(197704)39:4<1647::aid-cncr2820390439>3.0.co;2-h. [DOI] [PubMed] [Google Scholar]
  20. WAGNER J. C., SLEGGS C. A., MARCHAND P. Diffuse pleural mesothelioma and asbestos exposure in the North Western Cape Province. Br J Ind Med. 1960 Oct;17:260–271. doi: 10.1136/oem.17.4.260. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Warnock M. L., Churg A. M. Association of asbestos and bronchogenic carcinoma in a population with low asbestos exposure. Cancer. 1975 Apr;35(4):1236–1242. doi: 10.1002/1097-0142(197504)35:4<1236::aid-cncr2820350431>3.0.co;2-5. [DOI] [PubMed] [Google Scholar]
  22. Whitwell F., Newhouse M. L., Bennett D. R. A study of the histological cell types of lung cancer in workers suffering from asbestosis in the United Kingdom. Br J Ind Med. 1974 Oct;31(4):298–303. doi: 10.1136/oem.31.4.298. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Whitwell F., Scott J., Grimshaw M. Relationship between occupations and asbestos-fibre content of the lungs in patients with pleural mesothelioma, lung cancer, and other diseases. Thorax. 1977 Aug;32(4):377–386. doi: 10.1136/thx.32.4.377. [DOI] [PMC free article] [PubMed] [Google Scholar]

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