Skip to main content
PMC home page
Genitourinary Medicine logoLink to Genitourinary Medicine
. 1985 Apr;61(2):109–113. doi: 10.1136/sti.61.2.109

Anaerobic bacteria and herpes simplex virus in genital ulceration.

A N Masfari, G R Kinghorn, S Hafiz, I G Barton, B I Duerden
PMCID: PMC1011778  PMID: 2984108

Abstract

Of 91 patients with genital ulceration, herpes simplex virus was isolated from 52 (57%) and Haemophilus ducreyi from 12 (13%); none had syphilis. The difference in incidence of other aerobes in patients and controls was not significant. Anaerobes, predominantly Bacteroides spp, were isolated from a large proportion (77%) of men and women patients with ulcers but from few control men. The most common anaerobic species were B asaccharolyticus and B ureolyticus, with fewer isolates of the melaninogenicus/oralis group. The bacterial flora of herpetic and non-herpetic ulcers were similar, but Candida albicans was isolated significantly more often from non-herpetic ulcers. Anaerobic bacteria may contribute to the pathogenesis of genital ulcers.

Full text

PDF
111

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amies C. R. A modified formula for the preparation of Stuart's Transport Medium. Can J Public Health. 1967 Jul;58(7):296–300. [PubMed] [Google Scholar]
  2. Brook I., Finegold S. M. Bacteriology of chronic otitis media. JAMA. 1979 Feb 2;241(5):487–488. [PubMed] [Google Scholar]
  3. Bye P. Cyclic cyproterone/ethinyloestradiol in acne. Lancet. 1983 Oct 15;2(8355):910–911. doi: 10.1016/s0140-6736(83)90892-9. [DOI] [PubMed] [Google Scholar]
  4. Catterall R. D. Candida albicans and the contraceptive pill. Lancet. 1966 Oct 15;2(7468):830–831. doi: 10.1016/s0140-6736(66)92256-2. [DOI] [PubMed] [Google Scholar]
  5. Chapel T., Brown W. J., Jeffries C., Stewart J. A. The microbiological flora of penile ulcerations. J Infect Dis. 1978 Jan;137(1):50–56. doi: 10.1093/infdis/137.1.50. [DOI] [PubMed] [Google Scholar]
  6. Chow A. W., Galpin J. E., Guze L. B. Clindamycin for treatment of sepsis caused by decubitus ulcers. J Infect Dis. 1977 Mar;135 (Suppl):S65–S68. doi: 10.1093/infdis/135.supplement.s65. [DOI] [PubMed] [Google Scholar]
  7. Chow A. W., Roser S. M., Brady F. A. Orofacial odontogenic infections. Ann Intern Med. 1978 Mar;88(3):392–402. doi: 10.7326/0003-4819-88-3-392. [DOI] [PubMed] [Google Scholar]
  8. Duerden B. I. The identification of gram-negative anaerobic bacilli isolated from clinical infections. J Hyg (Lond) 1980 Apr;84(2):301–313. doi: 10.1017/s0022172400026802. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Duerden B. I. The isolation and identification of Bacteroides ssp. from the normal human vaginal flora. J Med Microbiol. 1980 Feb;13(1):79–87. doi: 10.1099/00222615-13-1-79. [DOI] [PubMed] [Google Scholar]
  10. Duerden B., Bennet K. W., Faulkner J. Isolation of Bacteroides ureolyticus (B corrodens) from clinical infections. J Clin Pathol. 1982 Mar;35(3):309–312. doi: 10.1136/jcp.35.3.309. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Fierer J., Daniel D., Davis C. The fetid foot: lower-extremity infections in patients with diabetes mellitus. Rev Infect Dis. 1979 Jan-Feb;1(1):210–217. doi: 10.1093/clinids/1.1.210. [DOI] [PubMed] [Google Scholar]
  12. Hafiz S., McEntegart M. G., Kinghorn G. R. Sheffield medium for cultivation of Haemophilus ducreyi. Br J Vener Dis. 1984 Jun;60(3):196–198. doi: 10.1136/sti.60.3.196. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Hammond G. W., Slutchuk M., Scatliff J., Sherman E., Wilt J. C., Ronald A. R. Epidemiologic, clinical, laboratory, and therapeutic features of an urban outbreak of chancroid in North America. Rev Infect Dis. 1980 Nov-Dec;2(6):867–879. doi: 10.1093/clinids/2.6.867. [DOI] [PubMed] [Google Scholar]
  14. Holbrook W. P., Ogston S. A., Ross P. W. A method for the isolation of Bacteroides melaninogenicus from the human mouth. J Med Microbiol. 1978 May;11(2):203–207. doi: 10.1099/00222615-11-2-203. [DOI] [PubMed] [Google Scholar]
  15. Hurley R. Recurrent Candida infection. Clin Obstet Gynaecol. 1981 Apr;8(1):209–214. [PubMed] [Google Scholar]
  16. Ingham H. R., Kalbag R. M., Tharagonnet D., High A. S., Sengupta R. P., Selkon J. B. Abscesses of the frontal lobe of the brain secondary to covert dental sepsis. Lancet. 1978 Sep 2;2(8088):497–499. doi: 10.1016/s0140-6736(78)92220-1. [DOI] [PubMed] [Google Scholar]
  17. Kinghorn G. R., Hafiz S., McEntegart M. G. Modified haemin-containing medium for isolation of Haemophilus ducreyi. Lancet. 1982 Feb 13;1(8268):393–394. doi: 10.1016/s0140-6736(82)91417-9. [DOI] [PubMed] [Google Scholar]
  18. Kinghorn G. R., Hafiz S., McEntegart M. G. Pathogenic microbial flora of genital ulcers in Sheffield with particular reference to herpes simplex virus and Haemophilus ducreyi. Br J Vener Dis. 1982 Dec;58(6):377–380. doi: 10.1136/sti.58.6.377. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Kinghorn G. R., Hafiz S. Sheffield isolates are Haemophilus ducreyi. Lancet. 1983 Nov 5;2(8358):1079–1079. doi: 10.1016/s0140-6736(83)91059-0. [DOI] [PubMed] [Google Scholar]
  20. Mallard R. H., Macaulay M. E., Riordan T., Chowdhury F. H., Chandiok S., Bhattacharyya M. N. Haemophilus ducreyi infection in Manchester. Lancet. 1983 Jul 30;2(8344):283–283. doi: 10.1016/s0140-6736(83)90265-9. [DOI] [PubMed] [Google Scholar]
  21. Masfari A. N., Kinghorn G. R., Duerden B. I. Anaerobes in genitourinary infections in men. Br J Vener Dis. 1983 Aug;59(4):255–259. doi: 10.1136/sti.59.4.255. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Meheus A., Van Dyck E., Friedman F. Genital infections in Swaziland. Ann Soc Belg Med Trop. 1982 Dec;62(4):361–367. [PubMed] [Google Scholar]
  23. Meislin H. W., Lerner S. A., Graves M. H., McGehee M. D., Kocka F. E., Morello J. A., Rosen P. Cutaneous abscesses. Anaerobic and aerobic bacteriology and outpatient management. Ann Intern Med. 1977 Aug;87(2):145–149. doi: 10.7326/0003-4819-87-2-145. [DOI] [PubMed] [Google Scholar]
  24. Nsanze H., Fast M. V., D'Costa L. J., Tukei P., Curran J., Ronald A. Genital ulcers in Kenya. Clinical and laboratory study. Br J Vener Dis. 1981 Dec;57(6):378–381. doi: 10.1136/sti.57.6.378. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Pearson H. E. Bacteroides in areolar breast abscesses. Surg Gynecol Obstet. 1967 Oct;125(4):800–806. [PubMed] [Google Scholar]

Articles from Genitourinary Medicine are provided here courtesy of BMJ Publishing Group

RESOURCES