Skip to main content
Journal of Medical Genetics logoLink to Journal of Medical Genetics
. 1978 Aug;15(4):254–259. doi: 10.1136/jmg.15.4.254

Genetic study of narcoleptic syndrome.

M Baraitser, J D Parkes
PMCID: PMC1013693  PMID: 712757

Abstract

In this family study of the narcoleptic syndrome, 52% of the probands had an affected first degree relative, 41.9% of the sibs of those probands with an affected parent were similarly affected, 33.3% of the parents of 2 affected sibs and 41.2% of the children (after a correction for age) had narcolepsy, cataplexy, or both.

Full text

PDF
255

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DALY D. D., YOSS R. E. A family with narcolepsy. Proc Staff Meet Mayo Clin. 1959 Jun 10;34:313–319. [PubMed] [Google Scholar]
  2. Gelardi J. M., Brown J. W. Hereditary cataplexy. J Neurol Neurosurg Psychiatry. 1967 Oct;30(5):455–457. doi: 10.1136/jnnp.30.5.455. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Guilleminault C., Carskadon M., Dement W. C. On the treatment of rapid eye movement narcolepsy. Arch Neurol. 1974 Jan;30(1):90–93. doi: 10.1001/archneur.1974.00490310092014. [DOI] [PubMed] [Google Scholar]
  4. IMLAH N. W. Narcolepsy in identical twins. J Neurol Neurosurg Psychiatry. 1961 May;24:158–160. doi: 10.1136/jnnp.24.2.158. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Kessler S., Guilleminault C., Dement W. A family study of 50 REM narcoleptics. Acta Neurol Scand. 1974;50(4):503–512. doi: 10.1111/j.1600-0404.1974.tb02796.x. [DOI] [PubMed] [Google Scholar]
  6. NEVSIMAL O., ROTH B. Prïpad rodinného výskytu narkolepsie. Cesk Neurol. 1958 Jan;21(1):54–58. [PubMed] [Google Scholar]
  7. RECHTSCHAFFEN A., WOLPERT E. A., DEMENT W. C., MITCHELL S. A., FISHER C. NOCTURNAL SLEEP OF NARCOLEPTICS. Electroencephalogr Clin Neurophysiol. 1963 Aug;15:599–609. doi: 10.1016/0013-4694(63)90032-4. [DOI] [PubMed] [Google Scholar]
  8. YOSS R. E., DALY D. D. Criteria for the diagnosis of the narcoleptic syndrome. Proc Staff Meet Mayo Clin. 1957 Jun 12;32(12):320–328. [PubMed] [Google Scholar]
  9. YOSS R. E., DALY D. D. Hereditary aspects of narcolepsy. Trans Am Neurol Assoc. 1960;85:239–240. [PubMed] [Google Scholar]

Articles from Journal of Medical Genetics are provided here courtesy of BMJ Publishing Group

RESOURCES