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. 1992 Sep;55(9):747–752. doi: 10.1136/jnnp.55.9.747

The ocular manifestations of multiple sclerosis. 1. Abnormalities of the afferent visual system.

W I McDonald 1, D Barnes 1
PMCID: PMC1015095  PMID: 1402963

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Selected References

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  1. Alvarez G., Cárdenas M. Multiple sclerosis following optic neuritis in Chile. J Neurol Neurosurg Psychiatry. 1989 Jan;52(1):115–117. doi: 10.1136/jnnp.52.1.115. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bamford C. R., Ganley J. P., Sibley W. A., Laguna J. F. Uveitis, perivenous sheathing and multiple sclerosis. Neurology. 1978 Sep;28(9 Pt 2):119–124. doi: 10.1212/wnl.28.9_part_2.119. [DOI] [PubMed] [Google Scholar]
  3. Bowden A. N., Bowden P. M., Friedmann A. I., Perkin G. D., Rose F. C. A trial of corticotrophin gelatin injection in acute optic neuritis. J Neurol Neurosurg Psychiatry. 1974 Aug;37(8):869–873. doi: 10.1136/jnnp.37.8.869. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Compston D. A., Batchelor J. R., Earl C. J., McDonald W. I. Factors influencing the risk of multiple sclerosis developing in patients with optic neuritis. Brain. 1978 Sep;101(3):495–511. doi: 10.1093/brain/101.3.495. [DOI] [PubMed] [Google Scholar]
  5. Davis F. A., Bergen D., Schauf C., McDonald I., Deutsch W. Movement phosphenes in optic neuritis: a new clinical sign. Neurology. 1976 Nov;26(11):1100–1104. doi: 10.1212/wnl.26.11.1100. [DOI] [PubMed] [Google Scholar]
  6. Dun V., Bale J. F., Jr, Zimmerman R. A., Perdue Z., Bell W. E. MRI in children with postinfectious disseminated encephalomyelitis. Magn Reson Imaging. 1986;4(1):25–32. doi: 10.1016/0730-725x(86)91086-6. [DOI] [PubMed] [Google Scholar]
  7. Ell J. J., Gresty M. A. Uniocular Pulfrich phenomenon: an abnormality of visual perception. Br J Ophthalmol. 1982 Sep;66(9):610–613. doi: 10.1136/bjo.66.9.610. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Francis D. A., Compston D. A., Batchelor J. R., McDonald W. I. A reassessment of the risk of multiple sclerosis developing in patients with optic neuritis after extended follow-up. J Neurol Neurosurg Psychiatry. 1987 Jun;50(6):758–765. doi: 10.1136/jnnp.50.6.758. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Frisén L., Hoyt W. F. Insidious atrophy of retinal nerve fibers in multiple sclerosis. Funduscopic identification in patients with and without visual complaints. Arch Ophthalmol. 1974 Aug;92(2):91–97. doi: 10.1001/archopht.1974.01010010097001. [DOI] [PubMed] [Google Scholar]
  10. Gould E. S., Bird A. C., Leaver P. K., McDonald W. I. Treatmenf of optic neuritis by retrobulbar injection of triamcinolone. Br Med J. 1977 Jun 11;1(6075):1495–1497. doi: 10.1136/bmj.1.6075.1495. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Graham E. M., Ellis C. J., Sanders M. D., McDonald W. I. Optic neuropathy in sarcoidosis. J Neurol Neurosurg Psychiatry. 1986 Jul;49(7):756–763. doi: 10.1136/jnnp.49.7.756. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Graham E. M., Francis D. A., Sanders M. D., Rudge P. Ocular inflammatory changes in established multiple sclerosis. J Neurol Neurosurg Psychiatry. 1989 Dec;52(12):1360–1363. doi: 10.1136/jnnp.52.12.1360. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. HIERONS R., LYLE T. K. Bilateral retrobulbar optic neuritis. Brain. 1959 Mar;82(1):56–67. doi: 10.1093/brain/82.1.56. [DOI] [PubMed] [Google Scholar]
  14. Halliday A. M., McDonald W. I., Mushin J. Delayed pattern-evoked responses in optic neuritis in relation to visual acuity. Trans Ophthalmol Soc U K. 1973;93(0):315–324. [PubMed] [Google Scholar]
  15. Hawkins C. P., Munro P. M., MacKenzie F., Kesselring J., Tofts P. S., du Boulay E. P., Landon D. N., McDonald W. I. Duration and selectivity of blood-brain barrier breakdown in chronic relapsing experimental allergic encephalomyelitis studied by gadolinium-DTPA and protein markers. Brain. 1990 Apr;113(Pt 2):365–378. doi: 10.1093/brain/113.2.365. [DOI] [PubMed] [Google Scholar]
  16. Hely M. A., McManis P. G., Doran T. J., Walsh J. C., McLeod J. G. Acute optic neuritis: a prospective study of risk factors for multiple sclerosis. J Neurol Neurosurg Psychiatry. 1986 Oct;49(10):1125–1130. doi: 10.1136/jnnp.49.10.1125. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Holt I. J., Miller D. H., Harding A. E. Genetic heterogeneity and mitochondrial DNA heteroplasmy in Leber's hereditary optic neuropathy. J Med Genet. 1989 Dec;26(12):739–743. doi: 10.1136/jmg.26.12.739. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Hornabrook R. S., Miller D. H., Newton M. R., MacManus D. G., du Boulay G. H., Halliday A. M., McDonald W. I. Frequent involvement of the optic radiation in patients with acute isolated optic neuritis. Neurology. 1992 Jan;42(1):77–79. doi: 10.1212/wnl.42.1.77. [DOI] [PubMed] [Google Scholar]
  19. Hutchinson W. M. Acute optic neuritis and the prognosis for multiple sclerosis. J Neurol Neurosurg Psychiatry. 1976 Mar;39(3):283–289. doi: 10.1136/jnnp.39.3.283. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Isayama Y., Takahashi T., Shimoyoma T., Yamadori A. Acute optic neuritis and multiple sclerosis. Neurology. 1982 Jan;32(1):73–76. doi: 10.1212/wnl.32.1.73. [DOI] [PubMed] [Google Scholar]
  21. Kermode A. G., Moseley I. F., Kendall B. E., Miller D. H., MacManus D. G., McDonald W. I. Magnetic resonance imaging in Leber's optic neuropathy. J Neurol Neurosurg Psychiatry. 1989 May;52(5):671–674. doi: 10.1136/jnnp.52.5.671. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Kermode A. G., Thompson A. J., Tofts P., MacManus D. G., Kendall B. E., Kingsley D. P., Moseley I. F., Rudge P., McDonald W. I. Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis. Pathogenetic and clinical implications. Brain. 1990 Oct;113(Pt 5):1477–1489. doi: 10.1093/brain/113.5.1477. [DOI] [PubMed] [Google Scholar]
  23. Kesselring J., Miller D. H., Robb S. A., Kendall B. E., Moseley I. F., Kingsley D., du Boulay E. P., McDonald W. I. Acute disseminated encephalomyelitis. MRI findings and the distinction from multiple sclerosis. Brain. 1990 Apr;113(Pt 2):291–302. doi: 10.1093/brain/113.2.291. [DOI] [PubMed] [Google Scholar]
  24. Kriss A., Francis D. A., Cuendet F., Halliday A. M., Taylor D. S., Wilson J., Keast-Butler J., Batchelor J. R., McDonald W. I. Recovery after optic neuritis in childhood. J Neurol Neurosurg Psychiatry. 1988 Oct;51(10):1253–1258. doi: 10.1136/jnnp.51.10.1253. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Lightman S., McDonald W. I., Bird A. C., Francis D. A., Hoskins A., Batchelor J. R., Halliday A. M. Retinal venous sheathing in optic neuritis. Its significance for the pathogenesis of multiple sclerosis. Brain. 1987 Apr;110(Pt 2):405–414. doi: 10.1093/brain/110.2.405. [DOI] [PubMed] [Google Scholar]
  26. McDonald W. I. Doyne lecture. The significance of optic neuritis. Trans Ophthalmol Soc U K. 1983;103(Pt 3):230–246. [PubMed] [Google Scholar]
  27. Meadows S. P. Doyne memorial lecture (1969). Retrobulbar and optic neuritis in childhood and adolescence. Trans Ophthalmol Soc U K. 1970;89:603–638. [PubMed] [Google Scholar]
  28. Miller D. H., Kay R., Schon F., McDonald W. I., Haas L. F., Hughes R. A. Optic neuritis following chickenpox in adults. J Neurol. 1986 Jun;233(3):182–184. doi: 10.1007/BF00314431. [DOI] [PubMed] [Google Scholar]
  29. Miller D. H., Newton M. R., van der Poel J. C., du Boulay E. P., Halliday A. M., Kendall B. E., Johnson G., MacManus D. G., Moseley I. F., McDonald W. I. Magnetic resonance imaging of the optic nerve in optic neuritis. Neurology. 1988 Feb;38(2):175–179. doi: 10.1212/wnl.38.2.175. [DOI] [PubMed] [Google Scholar]
  30. Miller D. H., Ormerod I. E., McDonald W. I., MacManus D. G., Kendall B. E., Kingsley D. P., Moseley I. F. The early risk of multiple sclerosis after optic neuritis. J Neurol Neurosurg Psychiatry. 1988 Dec;51(12):1569–1571. doi: 10.1136/jnnp.51.12.1569. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Moulin D., Paty D. W., Ebers G. C. The predictive value of cerebrospinal fluid electrophoresis in 'possible' multiple sclerosis. Brain. 1983 Dec;106(Pt 4):809–816. doi: 10.1093/brain/106.4.809. [DOI] [PubMed] [Google Scholar]
  32. Mullen K. T., Plant G. T. Colour and luminance vision in human optic neuritis. Brain. 1986 Feb;109(Pt 1):1–13. doi: 10.1093/brain/109.1.1. [DOI] [PubMed] [Google Scholar]
  33. Ormerod I. E., McDonald W. I. Multiple sclerosis presenting with progressive visual failure. J Neurol Neurosurg Psychiatry. 1984 Sep;47(9):943–946. doi: 10.1136/jnnp.47.9.943. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Parkin P. J., Hierons R., McDonald W. I. Bilateral optic neuritis. A long-term follow-up. Brain. 1984 Sep;107(Pt 3):951–964. doi: 10.1093/brain/107.3.951. [DOI] [PubMed] [Google Scholar]
  35. Parmley V. C., Schiffman J. S., Maitland C. G., Miller N. R., Dreyer R. F., Hoyt W. F. Does neuroretinitis rule out multiple sclerosis? Arch Neurol. 1987 Oct;44(10):1045–1048. doi: 10.1001/archneur.1987.00520220047015. [DOI] [PubMed] [Google Scholar]
  36. Persson H. E., Sachs C. Visual evoked potentials elicited by pattern reversal during provoked visual impairment in multiple sclerosis. Brain. 1981 Jun;104(2):369–382. doi: 10.1093/brain/104.2.369. [DOI] [PubMed] [Google Scholar]
  37. Plant G. T., Kermode A. G., Turano G., Moseley I. F., Miller D. H., MacManus D. G., Halliday A. M., McDonald W. I. Symptomatic retrochiasmal lesions in multiple sclerosis: clinical features, visual evoked potentials, and magnetic resonance imaging. Neurology. 1992 Jan;42(1):68–76. doi: 10.1212/wnl.42.1.68. [DOI] [PubMed] [Google Scholar]
  38. Rasminsky M. The effects of temperature on conduction in demyelinated single nerve fibers. Arch Neurol. 1973 May;28(5):287–292. doi: 10.1001/archneur.1973.00490230023001. [DOI] [PubMed] [Google Scholar]
  39. Rawson M. D., Liversedge L. A., Goldfarb G. Treatment of acute retrobulbar neuritis with corticotrophin. Lancet. 1966 Nov 12;2(7472):1044–1046. doi: 10.1016/s0140-6736(66)92025-3. [DOI] [PubMed] [Google Scholar]
  40. Rizzo J. F., 3rd, Lessell S. Risk of developing multiple sclerosis after uncomplicated optic neuritis: a long-term prospective study. Neurology. 1988 Feb;38(2):185–190. doi: 10.1212/wnl.38.2.185. [DOI] [PubMed] [Google Scholar]
  41. Rushton D. Use of the Pulfrich pendulum for detecting abnormal delay in the visual pathway in multiple sclerosis. Brain. 1975 Jun;98(2):283–296. doi: 10.1093/brain/98.2.283. [DOI] [PubMed] [Google Scholar]
  42. Sandberg-Wollheim M., Bynke H., Cronqvist S., Holtås S., Platz P., Ryder L. P. A long-term prospective study of optic neuritis: evaluation of risk factors. Ann Neurol. 1990 Apr;27(4):386–393. doi: 10.1002/ana.410270406. [DOI] [PubMed] [Google Scholar]
  43. Smith K. J., McDonald W. I. Spontaneous and mechanically evoked activity due to central demyelinating lesion. Nature. 1980 Jul 10;286(5769):154–155. doi: 10.1038/286154a0. [DOI] [PubMed] [Google Scholar]
  44. Thompson A. J., Kermode A. G., Wicks D., MacManus D. G., Kendall B. E., Kingsley D. P., McDonald W. I. Major differences in the dynamics of primary and secondary progressive multiple sclerosis. Ann Neurol. 1991 Jan;29(1):53–62. doi: 10.1002/ana.410290111. [DOI] [PubMed] [Google Scholar]
  45. Wallace D. C., Singh G., Lott M. T., Hodge J. A., Schurr T. G., Lezza A. M., Elsas L. J., 2nd, Nikoskelainen E. K. Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy. Science. 1988 Dec 9;242(4884):1427–1430. doi: 10.1126/science.3201231. [DOI] [PubMed] [Google Scholar]
  46. Willoughby E. W., Grochowski E., Li D. K., Oger J., Kastrukoff L. F., Paty D. W. Serial magnetic resonance scanning in multiple sclerosis: a second prospective study in relapsing patients. Ann Neurol. 1989 Jan;25(1):43–49. doi: 10.1002/ana.410250107. [DOI] [PubMed] [Google Scholar]
  47. Youl B. D., Turano G., Miller D. H., Towell A. D., MacManus D. G., Moore S. G., Jones S. J., Barrett G., Kendall B. E., Moseley I. F. The pathophysiology of acute optic neuritis. An association of gadolinium leakage with clinical and electrophysiological deficits. Brain. 1991 Dec;114(Pt 6):2437–2450. doi: 10.1093/brain/114.6.2437. [DOI] [PubMed] [Google Scholar]

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