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. 1993 Aug;30(8):638–639. doi: 10.1136/jmg.30.8.638

Association and linkage: complementary strategies for complex disorders.

M J Owen, P McGuffin
PMCID: PMC1016489  PMID: 8411048

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bain S. C., Prins J. B., Hearne C. M., Rodrigues N. R., Rowe B. R., Pritchard L. E., Ritchie R. J., Hall J. R., Undlien D. E., Ronningen K. S. Insulin gene region-encoded susceptibility to type 1 diabetes is not restricted to HLA-DR4-positive individuals. Nat Genet. 1992 Nov;2(3):212–215. doi: 10.1038/ng1192-212. [DOI] [PubMed] [Google Scholar]
  2. Bell G. I., Horita S., Karam J. H. A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus. Diabetes. 1984 Feb;33(2):176–183. doi: 10.2337/diab.33.2.176. [DOI] [PubMed] [Google Scholar]
  3. Chiu K. C., Province M. A., Permutt M. A. Glucokinase gene is genetic marker for NIDDM in American blacks. Diabetes. 1992 Jul;41(7):843–849. doi: 10.2337/diab.41.7.843. [DOI] [PubMed] [Google Scholar]
  4. Clerget-Darpoux F., Babron M. C., Prum B., Lathrop G. M., Deschamps I., Hors J. A new method to test genetic models in HLA associated diseases: the MASC method. Ann Hum Genet. 1988 Jul;52(Pt 3):247–258. doi: 10.1111/j.1469-1809.1988.tb01102.x. [DOI] [PubMed] [Google Scholar]
  5. Falk C. T., Rubinstein P. Haplotype relative risks: an easy reliable way to construct a proper control sample for risk calculations. Ann Hum Genet. 1987 Jul;51(Pt 3):227–233. doi: 10.1111/j.1469-1809.1987.tb00875.x. [DOI] [PubMed] [Google Scholar]
  6. Goate A., Chartier-Harlin M. C., Mullan M., Brown J., Crawford F., Fidani L., Giuffra L., Haynes A., Irving N., James L. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature. 1991 Feb 21;349(6311):704–706. doi: 10.1038/349704a0. [DOI] [PubMed] [Google Scholar]
  7. Greenberg D. A. There is more than one way to collect data for linkage analysis. What a study of epilepsy can tell us about linkage strategy for psychiatric disease. Arch Gen Psychiatry. 1992 Sep;49(9):745–750. doi: 10.1001/archpsyc.1992.01820090073012. [DOI] [PubMed] [Google Scholar]
  8. Groop L. C., Kankuri M., Schalin-Jäntti C., Ekstrand A., Nikula-Ijäs P., Widén E., Kuismanen E., Eriksson J., Franssila-Kallunki A., Saloranta C. Association between polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus. N Engl J Med. 1993 Jan 7;328(1):10–14. doi: 10.1056/NEJM199301073280102. [DOI] [PubMed] [Google Scholar]
  9. Hall J. M., Lee M. K., Newman B., Morrow J. E., Anderson L. A., Huey B., King M. C. Linkage of early-onset familial breast cancer to chromosome 17q21. Science. 1990 Dec 21;250(4988):1684–1689. doi: 10.1126/science.2270482. [DOI] [PubMed] [Google Scholar]
  10. Hyer R. N., Julier C., Buckley J. D., Trucco M., Rotter J., Spielman R., Barnett A., Bain S., Boitard C., Deschamps I. High-resolution linkage mapping for susceptibility genes in human polygenic disease: insulin-dependent diabetes mellitus and chromosome 11q. Am J Hum Genet. 1991 Feb;48(2):243–257. [PMC free article] [PubMed] [Google Scholar]
  11. McGue M., Gottesman I. I. Genetic linkage in schizophrenia: perspectives from genetic epidemiology. Schizophr Bull. 1989;15(3):453–464. doi: 10.1093/schbul/15.3.453. [DOI] [PubMed] [Google Scholar]
  12. McGuffin P., Sturt E. Genetic markers in schizophrenia. Hum Hered. 1986;36(2):65–88. doi: 10.1159/000153604. [DOI] [PubMed] [Google Scholar]
  13. O'Donovan M. C., Owen M. J. Advances and retreats in the molecular genetics of major mental illness. Ann Med. 1992 Jun;24(3):171–177. doi: 10.3109/07853899209147816. [DOI] [PubMed] [Google Scholar]
  14. Owen M. J. Will schizophrenia become a graveyard for molecular geneticists? Psychol Med. 1992 May;22(2):289–293. doi: 10.1017/s0033291700030221. [DOI] [PubMed] [Google Scholar]
  15. Owen M., McGuffin P. The molecular genetics of schizophrenia. BMJ. 1992 Sep 19;305(6855):664–665. doi: 10.1136/bmj.305.6855.664. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Plomin R. The role of inheritance in behavior. Science. 1990 Apr 13;248(4952):183–188. doi: 10.1126/science.2183351. [DOI] [PubMed] [Google Scholar]
  17. Risch N. Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet. 1990 Feb;46(2):222–228. [PMC free article] [PubMed] [Google Scholar]
  18. Schellenberg G. D., Bird T. D., Wijsman E. M., Orr H. T., Anderson L., Nemens E., White J. A., Bonnycastle L., Weber J. L., Alonso M. E. Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14. Science. 1992 Oct 23;258(5082):668–671. doi: 10.1126/science.1411576. [DOI] [PubMed] [Google Scholar]
  19. Sobell J. L., Heston L. L., Sommer S. S. Delineation of genetic predisposition to multifactorial disease: a general approach on the threshold of feasibility. Genomics. 1992 Jan;12(1):1–6. doi: 10.1016/0888-7543(92)90398-c. [DOI] [PubMed] [Google Scholar]
  20. Sturt E., McGuffin P. Can linkage and marker association resolve the genetic aetiology of psychiatric disorders? Review and argument. Psychol Med. 1985 Aug;15(3):455–462. doi: 10.1017/s0033291700031330. [DOI] [PubMed] [Google Scholar]
  21. Terwilliger J. D., Ott J. A haplotype-based 'haplotype relative risk' approach to detecting allelic associations. Hum Hered. 1992;42(6):337–346. doi: 10.1159/000154096. [DOI] [PubMed] [Google Scholar]
  22. Tienari P. J., Wikström J., Sajantila A., Palo J., Peltonen L. Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene. Lancet. 1992 Oct 24;340(8826):987–991. doi: 10.1016/0140-6736(92)93007-a. [DOI] [PubMed] [Google Scholar]
  23. Todd J. A. La carte des microsatellites est arrivée! [The map of microsatellites has arrived!]. Hum Mol Genet. 1992 Dec;1(9):663–666. doi: 10.1093/hmg/1.9.663. [DOI] [PubMed] [Google Scholar]
  24. Vintiner G. M., Holder S. E., Winter R. M., Malcolm S. No evidence of linkage between the transforming growth factor-alpha gene in families with apparently autosomal dominant inheritance of cleft lip and palate. J Med Genet. 1992 Jun;29(6):393–397. doi: 10.1136/jmg.29.6.393. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Vionnet N., Stoffel M., Takeda J., Yasuda K., Bell G. I., Zouali H., Lesage S., Velho G., Iris F., Passa P. Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus. Nature. 1992 Apr 23;356(6371):721–722. doi: 10.1038/356721a0. [DOI] [PubMed] [Google Scholar]
  26. Weissenbach J., Gyapay G., Dib C., Vignal A., Morissette J., Millasseau P., Vaysseix G., Lathrop M. A second-generation linkage map of the human genome. Nature. 1992 Oct 29;359(6398):794–801. doi: 10.1038/359794a0. [DOI] [PubMed] [Google Scholar]

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