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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1994 Nov;57(Suppl):6–8. doi: 10.1136/jnnp.57.suppl.6

Immunomodulating effects of intravenous immunoglobulin in autoimmune and inflammatory diseases.

S V Kaveri 1, L Mouthon 1, M D Kazatchkine 1
PMCID: PMC1016714  PMID: 7964857

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Atlas E., Freedman J., Blanchette V., Kazatchkine M. D., Semple J. W. Downregulation of the anti-HLA alloimmune response by variable region-reactive (anti-idiotypic) antibodies in leukemic patients transfused with platelet concentrates. Blood. 1993 Jan 15;81(2):538–542. [PubMed] [Google Scholar]
  2. Basta M., Kirshbom P., Frank M. M., Fries L. F. Mechanism of therapeutic effect of high-dose intravenous immunoglobulin. Attenuation of acute, complement-dependent immune damage in a guinea pig model. J Clin Invest. 1989 Dec;84(6):1974–1981. doi: 10.1172/JCI114387. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Basta M., Langlois P. F., Marques M., Frank M. M., Fries L. F. High-dose intravenous immunoglobulin modifies complement-mediated in vivo clearance. Blood. 1989 Jul;74(1):326–333. [PubMed] [Google Scholar]
  4. Berchtold P., Dale G. L., Tani P., McMillan R. Inhibition of autoantibody binding to platelet glycoprotein IIb/IIIa by anti-idiotypic antibodies in intravenous gammaglobulin. Blood. 1989 Nov 15;74(7):2414–2417. [PubMed] [Google Scholar]
  5. Clarkson S. B., Bussel J. B., Kimberly R. P., Valinsky J. E., Nachman R. L., Unkeless J. C. Treatment of refractory immune thrombocytopenic purpura with an anti-Fc gamma-receptor antibody. N Engl J Med. 1986 May 8;314(19):1236–1239. doi: 10.1056/NEJM198605083141907. [DOI] [PubMed] [Google Scholar]
  6. Clayberger C., Lyu S. C., Pouletty P., Krensky A. M. Peptides corresponding to T-cell receptor-HLA contact regions inhibit class I-restricted immune responses. Transplant Proc. 1993 Feb;25(1 Pt 1):477–478. [PubMed] [Google Scholar]
  7. Dietrich G., Varela F. J., Hurez V., Bouanani M., Kazatchkine M. D. Selection of the expressed B cell repertoire by infusion of normal immunoglobulin G in a patient with autoimmune thyroiditis. Eur J Immunol. 1993 Nov;23(11):2945–2950. doi: 10.1002/eji.1830231133. [DOI] [PubMed] [Google Scholar]
  8. Engelhard D., Waner J. L., Kapoor N., Good R. A. Effect of intravenous immune globulin on natural killer cell activity: possible association with autoimmune neutropenia and idiopathic thrombocytopenia. J Pediatr. 1986 Jan;108(1):77–81. doi: 10.1016/s0022-3476(86)80772-7. [DOI] [PubMed] [Google Scholar]
  9. Fehr J., Hofmann V., Kappeler U. Transient reversal of thrombocytopenia in idiopathic thrombocytopenic purpura by high-dose intravenous gamma globulin. N Engl J Med. 1982 May 27;306(21):1254–1258. doi: 10.1056/NEJM198205273062102. [DOI] [PubMed] [Google Scholar]
  10. Kimberly R. P., Salmon J. E., Bussel J. B., Crow M. K., Hilgartner M. W. Modulation of mononuclear phagocyte function by intravenous gamma-globulin. J Immunol. 1984 Feb;132(2):745–750. [PubMed] [Google Scholar]
  11. Lin R. Y., Racis S. P. In vivo reduction of circulating C1q binding immune complexes by intravenous gammaglobulin administration. Int Arch Allergy Appl Immunol. 1986;79(3):286–290. doi: 10.1159/000233988. [DOI] [PubMed] [Google Scholar]
  12. Marchalonis J. J., Kaymaz H., Dedeoglu F., Schluter S. F., Yocum D. E., Edmundson A. B. Human autoantibodies reactive with synthetic autoantigens from T-cell receptor beta chain. Proc Natl Acad Sci U S A. 1992 Apr 15;89(8):3325–3329. doi: 10.1073/pnas.89.8.3325. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Marchalonis J. J., Kaymaz H., Dedeoglu F., Schluter S. F., Yocum D. E., Edmundson A. B. Human autoantibodies reactive with synthetic autoantigens from T-cell receptor beta chain. Proc Natl Acad Sci U S A. 1992 Apr 15;89(8):3325–3329. doi: 10.1073/pnas.89.8.3325. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Ronda N., Haury M., Nobrega A., Coutinho A., Kazatchkine M. D. Selectivity of recognition of variable (V) regions of autoantibodies by intravenous immunoglobulin (IVIg). Clin Immunol Immunopathol. 1994 Feb;70(2):124–128. doi: 10.1006/clin.1994.1019. [DOI] [PubMed] [Google Scholar]
  15. Rossi F., Dietrich G., Kazatchkine M. D. Anti-idiotypes against autoantibodies in normal immunoglobulins: evidence for network regulation of human autoimmune responses. Immunol Rev. 1989 Aug;110:135–149. doi: 10.1111/j.1600-065x.1989.tb00031.x. [DOI] [PubMed] [Google Scholar]
  16. Rossi F., Jayne D. R., Lockwood C. M., Kazatchkine M. D. Anti-idiotypes against anti-neutrophil cytoplasmic antigen autoantibodies in normal human polyspecific IgG for therapeutic use and in the remission sera of patients with systemic vasculitis. Clin Exp Immunol. 1991 Feb;83(2):298–303. doi: 10.1111/j.1365-2249.1991.tb05631.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Rossi F., Kazatchkine M. D. Antiidiotypes against autoantibodies in pooled normal human polyspecific Ig. J Immunol. 1989 Dec 15;143(12):4104–4109. [PubMed] [Google Scholar]
  18. Ruiz-Arguelles A. Spontaneous reversal of acquired autoimmune dysfibrinogenemia probably due to an antiidiotypic antibody directed to an interspecies cross-reactive idiotype expressed on antifibrinogen antibodies. J Clin Invest. 1988 Sep;82(3):958–963. doi: 10.1172/JCI113704. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Salama A., Mueller-Eckhardt C., Kiefel V. Effect of intravenous immunoglobulin in immune thrombocytopenia. Lancet. 1983 Jul 23;2(8343):193–195. doi: 10.1016/s0140-6736(83)90175-7. [DOI] [PubMed] [Google Scholar]
  20. Saoudi A., Hurez V., de Kozak Y., Kuhn J., Kaveri S. V., Kazatchkine M. D., Druet P., Bellon B. Human immunoglobulin preparations for intravenous use prevent experimental autoimmune uveoretinitis. Int Immunol. 1993 Dec;5(12):1559–1567. doi: 10.1093/intimm/5.12.1559. [DOI] [PubMed] [Google Scholar]
  21. Sultan Y., Rossi F., Kazatchkine M. D. Recovery from anti-VIII:C (antihemophilic factor) autoimmune disease is dependent on generation of antiidiotypes against anti-VIII:C autoantibodies. Proc Natl Acad Sci U S A. 1987 Feb;84(3):828–831. doi: 10.1073/pnas.84.3.828. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Varela F., Andersson A., Dietrich G., Sundblad A., Holmberg D., Kazatchkine M., Coutinho A. Population dynamics of natural antibodies in normal and autoimmune individuals. Proc Natl Acad Sci U S A. 1991 Jul 1;88(13):5917–5921. doi: 10.1073/pnas.88.13.5917. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Vassilev T., Gelin C., Kaveri S. V., Zilber M. T., Boumsell L., Kazatchkine M. D. Antibodies to the CD5 molecule in normal human immunoglobulins for therapeutic use (intravenous immunoglobulins, IVIg). Clin Exp Immunol. 1993 Jun;92(3):369–372. doi: 10.1111/j.1365-2249.1993.tb03407.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Zouali M., Eyquem A. Idiotypic/antiidiotypic interactions in systemic lupus erythematosus: demonstration of oscillating levels of anti-DNA autoantibodies and reciprocal antiidiotypic activity in a single patient. Ann Immunol (Paris) 1983 May-Jun;134C(3):377–391. [PubMed] [Google Scholar]
  25. van Doorn P. A., Rossi F., Brand A., van Lint M., Vermeulen M., Kazatchkine M. D. On the mechanism of high-dose intravenous immunoglobulin treatment of patients with chronic inflammatory demyelinating polyneuropathy. J Neuroimmunol. 1990 Sep-Oct;29(1-3):57–64. doi: 10.1016/0165-5728(90)90147-f. [DOI] [PubMed] [Google Scholar]

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