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. 1990 Jun;27(6):345–347. doi: 10.1136/jmg.27.6.345

Dystrophin expression and genotypic analysis of two cases of benign X linked myopathy (McLeod's syndrome).

N D Carter 1, J E Morgan 1, A P Monaco 1, M S Schwartz 1, S Jeffery 1
PMCID: PMC1017128  PMID: 2193159

Abstract

DNA extraction and Southern blot analysis of two cases of McLeod's syndrome showed restriction fragments identical to normal controls using probes from the Xp21 (1-2) region, in contrast to striking deletions found in two other McLeod phenotypes studied in the USA. The McLeod locus is adjacent to Duchenne muscular dystrophy (DMD) and dystrophin immunocytochemistry showed that expression is normal in muscle from the two McLeod cases in spite of the mild DMD-like myopathy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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