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Journal of Medical Genetics logoLink to Journal of Medical Genetics
. 1990 Jun;27(6):392–394. doi: 10.1136/jmg.27.6.392

Winglets of the eye: dominant transmission of early adult pterygium of the conjunctiva.

F Hecht 1, M G Shoptaugh 1
PMCID: PMC1017140  PMID: 2359104

Abstract

A pterygium, a wing-like thickening, of the bulbar conjunctiva is of environmental interest because it can occur on prolonged exposure to wind and weather. We describe a family with pterygium in two generations without a history of unusual exposure to the elements. There were six females and five males (including a set of male twins) with seven bilateral and four unilateral pterygia. The onset was unique in being in early adulthood, from the late teens through the twenties. This new genetic form can be distinguished by the age of onset from congenital and mid-adult pterygia, which are inherited as autosomal dominant traits. Irrespective of age, the treatment of conjunctival pterygium is surgical excision.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Clear A. S., Chirambo M. C., Hutt M. S. Solar keratosis, pterygium, and squamous cell carcinoma of the conjunctiva in Malawi. Br J Ophthalmol. 1979 Feb;63(2):102–109. doi: 10.1136/bjo.63.2.102. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Dhir S. P., Detels R., Alexander E. R. The role of environmental factors in cataract, pterygium and trachoma. Am J Ophthalmol. 1967 Jul;64(1):128–135. doi: 10.1016/0002-9394(67)93353-3. [DOI] [PubMed] [Google Scholar]
  3. HILGERS J. H. Pterygium: its incidence, heredity and etiology. Am J Ophthalmol. 1960 Oct;50:635–644. doi: 10.1016/0002-9394(60)90245-2. [DOI] [PubMed] [Google Scholar]
  4. JACKLIN H. N. FAMILIAL PREDISPOSITION TO PTERYGIUM FORMATION; REPORT OF A FAMILY. Am J Ophthalmol. 1964 Mar;57:481–482. doi: 10.1016/0002-9394(64)92668-6. [DOI] [PubMed] [Google Scholar]
  5. Murken J. D., Dannheim R. Zur Genetik des Pterygium corneae. Klin Monbl Augenheilkd. 1965 Nov;147(4):574–579. [PubMed] [Google Scholar]
  6. Taylor H. R. Aetiology of climatic droplet keratopathy and pterygium. Br J Ophthalmol. 1980 Mar;64(3):154–163. doi: 10.1136/bjo.64.3.154. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Zhang J. D. An investigation of aetiology and heredity of pterygium. Report of 11 cases in a family. Acta Ophthalmol (Copenh) 1987 Aug;65(4):413–416. doi: 10.1111/j.1755-3768.1987.tb07016.x. [DOI] [PubMed] [Google Scholar]

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