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. 1993 Jan;69(1 Suppl):S3–S11. doi: 10.1136/hrt.69.1_suppl.s3

Atherosclerosis: what is it and why does it occur?

M J Davies 1,2, N Woolf 1,2
PMCID: PMC1025252  PMID: 8427761

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ambrose J. A., Winters S. L., Arora R. R., Haft J. I., Goldstein J., Rentrop K. P., Gorlin R., Fuster V. Coronary angiographic morphology in myocardial infarction: a link between the pathogenesis of unstable angina and myocardial infarction. J Am Coll Cardiol. 1985 Dec;6(6):1233–1238. doi: 10.1016/s0735-1097(85)80207-2. [DOI] [PubMed] [Google Scholar]
  2. Bøtker H. E., Ravkilde J., Søgaard P., Jørgensen P. J., Hørder M., Thygesen K. Gradation of unstable angina based on a sensitive immunoassay for serum creatine kinase MB. Br Heart J. 1991 Feb;65(2):72–76. doi: 10.1136/hrt.65.2.72. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bürrig K. F. The endothelium of advanced arteriosclerotic plaques in humans. Arterioscler Thromb. 1991 Nov-Dec;11(6):1678–1689. [PubMed] [Google Scholar]
  4. Davies M. J., Bland J. M., Hangartner J. R., Angelini A., Thomas A. C. Factors influencing the presence or absence of acute coronary artery thrombi in sudden ischaemic death. Eur Heart J. 1989 Mar;10(3):203–208. doi: 10.1093/oxfordjournals.eurheartj.a059467. [DOI] [PubMed] [Google Scholar]
  5. Davies M. J., Thomas A. C., Knapman P. A., Hangartner J. R. Intramyocardial platelet aggregation in patients with unstable angina suffering sudden ischemic cardiac death. Circulation. 1986 Mar;73(3):418–427. doi: 10.1161/01.cir.73.3.418. [DOI] [PubMed] [Google Scholar]
  6. Davies M. J., Woolf N., Rowles P. M., Pepper J. Morphology of the endothelium over atherosclerotic plaques in human coronary arteries. Br Heart J. 1988 Dec;60(6):459–464. doi: 10.1136/hrt.60.6.459. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Deupree R. H., Fields R. I., McMahan C. A., Strong J. P. Atherosclerotic lesions and coronary heart disease. Key relationships in necropsied cases. Lab Invest. 1973 Feb;28(2):252–262. [PubMed] [Google Scholar]
  8. Faggiotto A., Ross R., Harker L. Studies of hypercholesterolemia in the nonhuman primate. I. Changes that lead to fatty streak formation. Arteriosclerosis. 1984 Jul-Aug;4(4):323–340. doi: 10.1161/01.atv.4.4.323. [DOI] [PubMed] [Google Scholar]
  9. Faggiotto A., Ross R. Studies of hypercholesterolemia in the nonhuman primate. II. Fatty streak conversion to fibrous plaque. Arteriosclerosis. 1984 Jul-Aug;4(4):341–356. doi: 10.1161/01.atv.4.4.341. [DOI] [PubMed] [Google Scholar]
  10. Falk E. Unstable angina with fatal outcome: dynamic coronary thrombosis leading to infarction and/or sudden death. Autopsy evidence of recurrent mural thrombosis with peripheral embolization culminating in total vascular occlusion. Circulation. 1985 Apr;71(4):699–708. doi: 10.1161/01.cir.71.4.699. [DOI] [PubMed] [Google Scholar]
  11. Forrester J. S., Litvack F., Grundfest W., Hickey A. A perspective of coronary disease seen through the arteries of living man. Circulation. 1987 Mar;75(3):505–513. doi: 10.1161/01.cir.75.3.505. [DOI] [PubMed] [Google Scholar]
  12. Fuster V., Badimon L., Badimon J. J., Chesebro J. H. The pathogenesis of coronary artery disease and the acute coronary syndromes (2). N Engl J Med. 1992 Jan 30;326(5):310–318. doi: 10.1056/NEJM199201303260506. [DOI] [PubMed] [Google Scholar]
  13. Glagov S., Weisenberg E., Zarins C. K., Stankunavicius R., Kolettis G. J. Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med. 1987 May 28;316(22):1371–1375. doi: 10.1056/NEJM198705283162204. [DOI] [PubMed] [Google Scholar]
  14. Hangartner J. R., Charleston A. J., Davies M. J., Thomas A. C. Morphological characteristics of clinically significant coronary artery stenosis in stable angina. Br Heart J. 1986 Dec;56(6):501–508. doi: 10.1136/hrt.56.6.501. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Lendon C. L., Davies M. J., Born G. V., Richardson P. D. Atherosclerotic plaque caps are locally weakened when macrophages density is increased. Atherosclerosis. 1991 Mar;87(1):87–90. doi: 10.1016/0021-9150(91)90235-u. [DOI] [PubMed] [Google Scholar]
  16. Restrepo C., Tracy R. E. Variations in human aortic fatty streaks among geographic locations. Atherosclerosis. 1975 Mar-Apr;21(2):179–193. doi: 10.1016/0021-9150(75)90079-9. [DOI] [PubMed] [Google Scholar]
  17. Richardson P. D., Davies M. J., Born G. V. Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques. Lancet. 1989 Oct 21;2(8669):941–944. doi: 10.1016/s0140-6736(89)90953-7. [DOI] [PubMed] [Google Scholar]
  18. Robertson W. B., Strong J. P. Atherosclerosis in persons with hypertension and diabetes mellitus. Lab Invest. 1968 May;18(5):538–551. [PubMed] [Google Scholar]
  19. Ross R. The pathogenesis of atherosclerosis--an update. N Engl J Med. 1986 Feb 20;314(8):488–500. doi: 10.1056/NEJM198602203140806. [DOI] [PubMed] [Google Scholar]
  20. Saner H. E., Gobel F. L., Salomonowitz E., Erlien D. A., Edwards J. E. The disease-free wall in coronary atherosclerosis: its relation to degree of obstruction. J Am Coll Cardiol. 1985 Nov;6(5):1096–1099. doi: 10.1016/s0735-1097(85)80314-4. [DOI] [PubMed] [Google Scholar]
  21. Small D. M., Bond M. G., Waugh D., Prack M., Sawyer J. K. Physicochemical and histological changes in the arterial wall of nonhuman primates during progression and regression of atherosclerosis. J Clin Invest. 1984 Jun;73(6):1590–1605. doi: 10.1172/JCI111366. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Steinberg D., Parthasarathy S., Carew T. E., Khoo J. C., Witztum J. L. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med. 1989 Apr 6;320(14):915–924. doi: 10.1056/NEJM198904063201407. [DOI] [PubMed] [Google Scholar]
  23. Wight T. N. Cell biology of arterial proteoglycans. Arteriosclerosis. 1989 Jan-Feb;9(1):1–20. doi: 10.1161/01.atv.9.1.1. [DOI] [PubMed] [Google Scholar]
  24. de Feyter P. J., Serruys P. W., Davies M. J., Richardson P., Lubsen J., Oliver M. F. Quantitative coronary angiography to measure progression and regression of coronary atherosclerosis. Value, limitations, and implications for clinical trials. Circulation. 1991 Jul;84(1):412–423. doi: 10.1161/01.cir.84.1.412. [DOI] [PubMed] [Google Scholar]

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