Skip to main content
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1984 Jul;47(7):699–703. doi: 10.1136/jnnp.47.7.699

Prognosis of alcoholic peripheral neuropathy.

M Hillbom, A Wennberg
PMCID: PMC1027897  PMID: 6086844

Abstract

Ten male alcoholics aged 38-72 years with clear clinical and electroneurographical signs of peripheral neuropathy were re-examined three to five years later. Conduction velocities, latencies and nerve action potential amplitudes were measured from median, peroneal and sural nerves on both occasions and the results were compared with age-matched reference values from 80 healthy men. Seven of the alcoholics showed normal or nearly normal scores in electroneurographical and clinical examination and they had all managed to stop drinking alcohol. The results suggest that the prognosis of alcoholic peripheral neuropathy is good and independent of age provided that intake of alcohol is discontinued and other causes of neuropathy (malignancy, diabetes, nerve trauma) are carefully excluded.

Full text

PDF
700

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ballantyne J. P., Hansen S., Weir A., Whitehead J. R., Mullin P. J. Quantitative electrophysiological study of alcoholic neuropathy. J Neurol Neurosurg Psychiatry. 1980 May;43(5):427–432. doi: 10.1136/jnnp.43.5.427. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. COUERS C., HILDEBRAND J. LATENT NEUROPATHY IN DIABETES AND ALCOHOLISM: ELECTROMYOGRAPHIC AND HISTOLOGICAL STUDY. Neurology. 1965 Jan;15:19–38. doi: 10.1212/wnl.15.1.19. [DOI] [PubMed] [Google Scholar]
  3. Casey E. B., Le Quesne P. M. Electrophysiological evidence for a distal lesion in alcoholic neuropathy. J Neurol Neurosurg Psychiatry. 1972 Oct;35(5):624–630. doi: 10.1136/jnnp.35.5.624. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Dart R. Alcoholic peripheral neuropathy. Nutr Rev. 1981 Jun;39(6):237–239. doi: 10.1111/j.1753-4887.1981.tb07449.x. [DOI] [PubMed] [Google Scholar]
  5. Elofsson S. A., Gamberale F., Hindmarsh T., Iregren A., Isaksson A., Johnsson I., Knave B., Lydahl E., Mindus P., Persson H. E. Exposure to organic solvents. A cross-sectional epidemiologic investigation on occupationally exposed care and industrial spray painters with special reference to the nervous system. Scand J Work Environ Health. 1980 Dec;6(4):239–273. doi: 10.5271/sjweh.2609. [DOI] [PubMed] [Google Scholar]
  6. FENNELLY J., FRANK O., BAKER H., LEEVY C. M. PERIPHERAL NEUROPATHY OF THE ALCOHOLIC: I, AETIOLOGICAL ROLE OF ANEURIN AND OTHER B-COMPLEX VITAMINS. Br Med J. 1964 Nov 21;2(5420):1290–1292. doi: 10.1136/bmj.2.5420.1290. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Gill G. V., Bell D. R. Persisting nutritional neuropathy amongst former war prisoners. J Neurol Neurosurg Psychiatry. 1982 Oct;45(10):861–865. doi: 10.1136/jnnp.45.10.861. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Hawley R. J., Kurtzke J. F., Armbrustmacher V. W., Saini N., Manz H. The course of alcoholic-nutritional peripheral neuropathy. Acta Neurol Scand. 1982 Nov;66(5):582–589. doi: 10.1111/j.1600-0404.1982.tb03146.x. [DOI] [PubMed] [Google Scholar]
  9. Kemppainen R., Juntunen J., Hillbom M. Drinking habits and peripheral alcoholic neuropathy. Acta Neurol Scand. 1982 Jan;65(1):11–18. doi: 10.1111/j.1600-0404.1982.tb03056.x. [DOI] [PubMed] [Google Scholar]
  10. Le Quesne P. M. Persisting nutritional neuropathy in former war prisoners. Br Med J (Clin Res Ed) 1983 Mar 19;286(6369):917–918. doi: 10.1136/bmj.286.6369.917-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Ward J. D., Barnes C. G., Fisher D. J., Jessop J. D., Baker R. W. Improvement in nerve conduction following treatment in newly diagnosed diabetics. Lancet. 1971 Feb 27;1(7696):428–430. doi: 10.1016/s0140-6736(71)92415-9. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES