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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1985 Jun;48(6):497–500. doi: 10.1136/jnnp.48.6.497

Hyperbaric oxygen in chronic progressive multiple sclerosis: visual evoked potentials and clinical effects.

J Neiman, B Y Nilsson, P O Barr, D J Perrins
PMCID: PMC1028364  PMID: 3891920

Abstract

The effects of hyperbaric oxygen at a pressure of two atmospheres absolute were studied in a group of patients with chronic progressive multiple sclerosis. A slight but statistically insignificant shortening of the visual evoked potential latencies was seen after treatment with hyperbaric oxygen as compared with placebo treatment. The treatment did not appreciably halt the progression of the disease and deferioration occurred more often among the patients in the treatment group than in the control group.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Boschetty V., Cernoch J. Aplikace kyslíku za pretlaku u nekterých neurologických onemocnení. (Predbezné sdelení) Bratisl Lek Listy. 1970 Mar;53(3):298–302. [PubMed] [Google Scholar]
  2. Brown J. R. Problems in evaluating new treatments for multiple sclerosis. Neurology. 1980 Jul;30(7 Pt 2):8–11. doi: 10.1212/wnl.30.7_part_2.8. [DOI] [PubMed] [Google Scholar]
  3. Fischer B. H., Marks M., Reich T. Hyperbaric-oxygen treatment of multiple sclerosis. A randomized, placebo-controlled, double-blind study. N Engl J Med. 1983 Jan 27;308(4):181–186. doi: 10.1056/NEJM198301273080402. [DOI] [PubMed] [Google Scholar]
  4. Golovkin V. I., Zaitsev V. S., Lotovin A. P. Giperbaricheskaia oksigenatsiia kak immunostimuliator pri rasseiannom skleroze. Sov Med. 1982;(12):70–75. [PubMed] [Google Scholar]
  5. Halliday A. M., McDonald W. I., Mushin J. Visual evoked response in diagnosis of multiple sclerosis. Br Med J. 1973 Dec 15;4(5893):661–664. doi: 10.1136/bmj.4.5893.661. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Hammond E. J., Ibarra E. L. Evoked potentials after hyperbaric oxygen treatment of multiple sclerosis. N Engl J Med. 1983 Jul 28;309(4):241–242. doi: 10.1056/NEJM198307283090412. [DOI] [PubMed] [Google Scholar]
  7. KURTZKE J. F. FURTHER NOTES ON DISABILITY EVALUATION IN MULTIPLE SCLEROSIS, WITH SCALE MODIFICATIONS. Neurology. 1965 Jul;15:654–661. doi: 10.1212/wnl.15.7.654. [DOI] [PubMed] [Google Scholar]
  8. Link H. Immunoglobulin G and low molecular weight proteins in human cerebrospinal fluid. Chemical and immunological characterisation with special reference to multiple sclerosis. Acta Neurol Scand. 1967;43(Suppl):1–136. [PubMed] [Google Scholar]
  9. Matthews W. B., Small D. G. Serial recording of visual and somatosensory evoked potentials in multiple sclerosis. J Neurol Sci. 1979 Jan;40(1):11–21. doi: 10.1016/0022-510x(79)90004-2. [DOI] [PubMed] [Google Scholar]
  10. Mertin J., McDonald W. I. Hyperbaric oxygen for patients with multiple sclerosis. Br Med J (Clin Res Ed) 1984 Mar 31;288(6422):957–960. doi: 10.1136/bmj.288.6422.957. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Neubauer R. A. Exposure of multiple sclerosis patients to hyperbaric oxygen at 1.5--2 ATA. A preliminary report. J Fla Med Assoc. 1980 May;67(5):498–504. [PubMed] [Google Scholar]
  12. Nilsson B. Y. Visual evoked responses in multiple sclerosis: comparison of two methods for pattern reversal. J Neurol Neurosurg Psychiatry. 1978 Jun;41(6):499–504. doi: 10.1136/jnnp.41.6.499. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Pallotta R. La terapia iperbarica della sclerosi multipla. Minerva Med. 1982 Nov 3;73(42):2947–2954. [PubMed] [Google Scholar]
  14. Poser C. M., Paty D. W., Scheinberg L., McDonald W. I., Davis F. A., Ebers G. C., Johnson K. P., Sibley W. A., Silberberg D. H., Tourtellotte W. W. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol. 1983 Mar;13(3):227–231. doi: 10.1002/ana.410130302. [DOI] [PubMed] [Google Scholar]
  15. Prockop L. D., Grasso R. J. Ameliorating effects of hyperbaric oxygenation on experimental allergic encephalomyelitis. Brain Res Bull. 1978 May-Jun;3(3):221–225. doi: 10.1016/0361-9230(78)90117-x. [DOI] [PubMed] [Google Scholar]
  16. Schumacher G. A. Critique of experimental trials of therapy in multiple sclerosis. Neurology. 1974 Nov;24(11):1010–1014. doi: 10.1212/wnl.24.11.1010. [DOI] [PubMed] [Google Scholar]
  17. Walsh J. C., Garrick R., Cameron J., McLeod J. G. Evoked potential changes in clinically definite multiple sclerosis: a two year follow up study. J Neurol Neurosurg Psychiatry. 1982 Jun;45(6):494–500. doi: 10.1136/jnnp.45.6.494. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Warren J., Sacksteder M. R., Thuning C. A. Oxygen immunosuppression: modification of experimental allergic encephalomyelitis in rodents. J Immunol. 1978 Jul;121(1):315–320. [PubMed] [Google Scholar]
  19. de Weerd A. W., Jonkman E. J. Changes in visual and short-latency somatosensory evoked potentials in patients with multiple sclerosis. Adv Neurol. 1982;32:527–534. [PubMed] [Google Scholar]

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