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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1988 Jan;51(1):21–27. doi: 10.1136/jnnp.51.1.21

Epidemiology of headache in the Republic of San Marino.

R D'Alessandro 1, G Benassi 1, P L Lenzi 1, G Gamberini 1, T Sacquegna 1, P De Carolis 1, E Lugaresi 1
PMCID: PMC1032709  PMID: 3258357

Abstract

An epidemiological survey on headache was performed in the Republic of San Marino, which is the smallest independent State in the world, located near the Adriatic Coast, within Italy. Among a random sample of 1500 inhabitants over 7 years of age the frequency of headache, severe headache and migraine in the previous year was 35.3%, 12.2%, 9.3% respectively for men, and 46.2%, 20.6%, 18% for women. The most common factors reported to provoke headache were emotional stress, physical strain, lack of sleep, particular foods or drinks and for women menstruation. Migraine patients differed from people without headache in that they had a higher consumption of coffee, more frequently reported bad sleep, allergic disease and previous appendectomy. Furthermore, migraine patients and severe headache sufferers had a higher diastolic blood pressure than non headache subjects.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Benassi G., D'Alessandro R., Lenzi P. L., Manzaroli D., Baldrati A., Lugaresi E. The economic burden of headache: an epidemiological study in the Republic of San Marino. Headache. 1986 Oct;26(9):457–459. doi: 10.1111/j.1526-4610.1986.hed2609457.x. [DOI] [PubMed] [Google Scholar]
  2. Bruyn G. W. Epidemiology of migraine 'a personal view'. Headache. 1983 May;23(3):127–133. [PubMed] [Google Scholar]
  3. Cheng X. M., Ziegler D. K., Li S. C., Dai Q. S., Chandra V., Schoenberg B. S. A prevalence survey of 'incapacitating headache' in the People's Republic of China. Neurology. 1986 Jun;36(6):831–834. doi: 10.1212/wnl.36.6.831. [DOI] [PubMed] [Google Scholar]
  4. Crisp A. H., Kalucy R. S., McGuinness B., Ralph P. C., Harris G. Some clinical, social and psychological characteristics of migraine subjects in the general population. Postgrad Med J. 1977 Nov;53(625):691–697. doi: 10.1136/pgmj.53.625.691. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Manzoni G. C., Campari M., Terzano M. G., Moretti G., Fanti E. An epidemiological study of headache in a hospital staff. Headache. 1981 Sep;21(5):206–210. doi: 10.1111/j.1526-4610.1981.hed2105206.x. [DOI] [PubMed] [Google Scholar]
  6. Markush R. E., Karp H. R., Heyman A., O'Fallon W. M. Epidemiologic study of migraine symptoms in young women. Neurology. 1975 May;25(5):430–435. doi: 10.1212/wnl.25.5.430. [DOI] [PubMed] [Google Scholar]
  7. Monro J., Brostoff J., Carini C., Zilkha K. Food allergy in migraine. Study of dietary exclusion and RAST. Lancet. 1980 Jul 5;2(8184):1–4. doi: 10.1016/s0140-6736(80)92887-1. [DOI] [PubMed] [Google Scholar]
  8. Musey V. C., Collins D. C., Musey P. I., Martino-Saltzman D., Preedy J. R. Long-term effect of a first pregnancy on the secretion of prolactin. N Engl J Med. 1987 Jan 29;316(5):229–234. doi: 10.1056/NEJM198701293160501. [DOI] [PubMed] [Google Scholar]
  9. Nikiforow R., Hokkanen E. An epidemiological study of headache in an urban and a rural population in northern Finland. Headache. 1978 Jul;18(3):137–145. doi: 10.1111/j.1526-4610.1978.hed1803137.x. [DOI] [PubMed] [Google Scholar]
  10. Paulin J. M., Waal-Manning H. J., Simpson F. O., Knight R. G. The prevalence of headache in a small New Zealand town. Headache. 1985 May;25(3):147–151. doi: 10.1111/j.1526-4610.1985.hed2503147.x. [DOI] [PubMed] [Google Scholar]
  11. Reichel H., Koeffler H. P., Bishop J. E., Norman A. W. 25-Hydroxyvitamin D3 metabolism by lipopolysaccharide-stimulated normal human macrophages. J Clin Endocrinol Metab. 1987 Jan;64(1):1–9. doi: 10.1210/jcem-64-1-1. [DOI] [PubMed] [Google Scholar]
  12. WALKER C. H. Migraine and its relationship to hypertension. Br Med J. 1959 Dec 26;2(5164):1430–1433. doi: 10.1136/bmj.2.5164.1430. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Wallenstein S., Zucker C. L., Fleiss J. L. Some statistical methods useful in circulation research. Circ Res. 1980 Jul;47(1):1–9. doi: 10.1161/01.res.47.1.1. [DOI] [PubMed] [Google Scholar]
  14. Waters W. E. Headache and blood pressure in the community. Br Med J. 1971 Jan 16;1(5741):142–143. doi: 10.1136/bmj.1.5741.142. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Waters W. E., O'Connor P. J. Epidemiology of headache and migraine in women. J Neurol Neurosurg Psychiatry. 1971 Apr;34(2):148–153. doi: 10.1136/jnnp.34.2.148. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Waters W. E., O'Connor P. J. Prevalence of migraine. J Neurol Neurosurg Psychiatry. 1975 Jun;38(6):613–616. doi: 10.1136/jnnp.38.6.613. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Waters W. E. The epidemiological enigma of migraine. Int J Epidemiol. 1973 Summer;2(2):189–194. doi: 10.1093/ije/2.2.189. [DOI] [PubMed] [Google Scholar]
  18. Ziegler D. K., Hassanein R. S., Couch J. R. Characteristics of life headache histories in a nonclinic population. Neurology. 1977 Mar;27(3):265–269. doi: 10.1212/wnl.27.3.265. [DOI] [PubMed] [Google Scholar]

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