Abstract
Eleven patients with brucellosis presented with neurological features closely simulating transient ischaemic attacks, cerebral infarction, acute confusional state, motor neuron disease, progressive multisystem degeneration, polyradiculoneuropathy, neuralgic amyotrophy, sciatica and cauda equina syndrome. Most patients improved quickly after adequate antibiotic treatment but chronic cases responded poorly. These protean neurological manifestations of brucellosis indicate that the underlying pathological mechanisms are diverse.
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Selected References
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- AGUILAR J. A., ELVIDGE A. R. Intervertebral disk disease caused by the Brucella organism. J Neurosurg. 1961 Jan;18:27–33. doi: 10.3171/jns.1961.18.1.0027. [DOI] [PubMed] [Google Scholar]
- Al-Orainey I. O., Laajam M. A., Al-Aska A. K., Rajapakse C. N. Brucella meningitis. J Infect. 1987 Mar;14(2):141–145. doi: 10.1016/s0163-4453(87)91952-9. [DOI] [PubMed] [Google Scholar]
- Bashir R., Al-Kawi M. Z., Harder E. J., Jinkins J. Nervous system brucellosis: diagnosis and treatment. Neurology. 1985 Nov;35(11):1576–1581. doi: 10.1212/wnl.35.11.1576. [DOI] [PubMed] [Google Scholar]
- FINCHAM R. W., SAHS A. L., JOYNT R. J. Protean manifestations of nervous system brucellosis. Case histories of a wide variety of clinical forms. JAMA. 1963 Apr 27;184:269–275. doi: 10.1001/jama.1963.03700170061009. [DOI] [PubMed] [Google Scholar]
- Kambal A. M., Mahgoub E. S., Jamjoom G. A., Chowdhury M. N. Brucellosis in Riyadh, Saudi Arabia. A microbiological and clinical study. Trans R Soc Trop Med Hyg. 1983;77(6):820–824. doi: 10.1016/0035-9203(83)90297-3. [DOI] [PubMed] [Google Scholar]
- Mousa A. R., Koshy T. S., Araj G. F., Marafie A. A., Muhtaseb S. A., Al-Mudallal D. S., Busharetulla M. S. Brucella meningitis: presentation, diagnosis and treatment--a prospective study of ten cases. Q J Med. 1986 Sep;60(233):873–885. [PubMed] [Google Scholar]
- PROGER S. CORONARY HEART-DISEASE. A CLINICAL VIEW. Lancet. 1964 Jan 4;1(7323):1–4. doi: 10.1016/s0140-6736(64)92155-5. [DOI] [PubMed] [Google Scholar]
- Shakir R. A., Al-Din A. S., Araj G. F., Lulu A. R., Mousa A. R., Saadah M. A. Clinical categories of neurobrucellosis. A report on 19 cases. Brain. 1987 Feb;110(Pt 1):213–223. doi: 10.1093/brain/110.1.213. [DOI] [PubMed] [Google Scholar]
- Young E. J. Human brucellosis. Rev Infect Dis. 1983 Sep-Oct;5(5):821–842. doi: 10.1093/clinids/5.5.821. [DOI] [PubMed] [Google Scholar]