Skip to main content
PMC home page
British Journal of Industrial Medicine logoLink to British Journal of Industrial Medicine
. 1990 Jul;47(7):473–479. doi: 10.1136/oem.47.7.473

Laryngeal cancer in Denmark: a nationwide longitudinal study based on register linkage data.

P Guenel 1, G Engholm 1, E Lynge 1
PMCID: PMC1035210  PMID: 2383517

Abstract

To identify high and low risk groups for laryngeal cancer in Denmark, all individuals aged 30-74 in the 1970 census were followed up over 10 years. Census data were linked with the Central Population Register to identify persons who died or emigrated during the follow up, and with the Danish Cancer Register to identify cases of laryngeal cancer. Individuals were categorised according to sex, age, and sociodemographic characteristics as declared on the census forms. A multivariate analysis was carried out by means of multiplicative Poisson models. The study showed that the risk of laryngeal cancer was strongly related to sociodemographic factors. The risk for skilled workers living in Copenhagen (relative risk (RR) 4.76, 95% confidence interval (CI) 3.61-6.28) was estimated to be almost five times higher than the risk for men self employed in agriculture and living in rural areas. The variation in the risk of laryngeal cancer is not fully explained by known variations in tobacco and alcohol consumption, and this study highlights additional risk factors particularly related to occupation and marital state.

Full text

PDF
477

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bertazzi P. A., Zocchetti C., Riboldi L., Pesatori A., Radice L., Latocca R. Cancer mortality of an Italian cohort of workers in man-made glass-fiber production. Scand J Work Environ Health. 1986;12 (Suppl 1):65–71. [PubMed] [Google Scholar]
  2. Brown L. M., Mason T. J., Pickle L. W., Stewart P. A., Buffler P. A., Burau K., Ziegler R. G., Fraumeni J. F., Jr Occupational risk factors for laryngeal cancer on the Texas Gulf Coast. Cancer Res. 1988 Apr 1;48(7):1960–1964. [PubMed] [Google Scholar]
  3. Burch J. D., Howe G. R., Miller A. B., Semenciw R. Tobacco, alcohol, asbestos, and nickel in the etiology of cancer of the larynx: a case-control study. J Natl Cancer Inst. 1981 Dec;67(6):1219–1224. [PubMed] [Google Scholar]
  4. Decoufle P. Cancer risks associated with employment in the leather and leather products industry. Arch Environ Health. 1979 Jan-Feb;34(1):33–37. doi: 10.1080/00039896.1979.10667364. [DOI] [PubMed] [Google Scholar]
  5. Forastiere F., Valesini S., Salimei E., Magliola M. E., Perucci C. A. Respiratory cancer among soap production workers. Scand J Work Environ Health. 1987 Jun;13(3):258–260. doi: 10.5271/sjweh.2053. [DOI] [PubMed] [Google Scholar]
  6. Guenel P., Møller H., Lynge E. Incidence of the upper respiratory and digestive tract cancers and consumption of alcohol and tobacco in Denmark. Scand J Soc Med. 1988;16(4):257–263. doi: 10.1177/140349488801600413. [DOI] [PubMed] [Google Scholar]
  7. Lynge E., Thygesen L. Use of surveillance systems for occupational cancer: data from the Danish National system. Int J Epidemiol. 1988 Sep;17(3):493–500. doi: 10.1093/ije/17.3.493. [DOI] [PubMed] [Google Scholar]
  8. Moulin J. J., Mur J. M., Wild P., Perreaux J. P., Pham Q. T. Oral cavity and laryngeal cancers among man-made mineral fiber production workers. Scand J Work Environ Health. 1986 Feb;12(1):27–31. doi: 10.5271/sjweh.2177. [DOI] [PubMed] [Google Scholar]
  9. Møller H., Guénel P. Karcinom i laebe, mund/pharynx og larynx i Danmark 1943-1982. Kraeftstatistik nr. 22. Ugeskr Laeger. 1988 Feb 22;150(8):493–497. [PubMed] [Google Scholar]
  10. Nielsen P. E., Zacho J., Olsen J. A., Olsen C. A. Aendringer i danskernes rygevaner 1970-1987. Ugeskr Laeger. 1988 Sep 19;150(38):2229–2233. [PubMed] [Google Scholar]
  11. Olsen J., Sabroe S., Lajer M. Welding and cancer of the larynx: a case-control study. Eur J Cancer Clin Oncol. 1984 May;20(5):639–643. doi: 10.1016/0277-5379(84)90010-5. [DOI] [PubMed] [Google Scholar]
  12. Olsen J., Sabroe S. Occupational causes of laryngeal cancer. J Epidemiol Community Health. 1984 Jun;38(2):117–121. doi: 10.1136/jech.38.2.117. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Pedersen E., Hogetveit A. C., Andersen A. Cancer of respiratory organs among workers at a nickel refinery in Norway. Int J Cancer. 1973 Jul 15;12(1):32–41. doi: 10.1002/ijc.2910120104. [DOI] [PubMed] [Google Scholar]
  14. Rothman K. J., Cann C. I., Flanders D., Fried M. P. Epidemiology of laryngeal cancer. Epidemiol Rev. 1980;2:195–209. doi: 10.1093/oxfordjournals.epirev.a036223. [DOI] [PubMed] [Google Scholar]
  15. Shettigara P. T., Morgan R. W. Asbestos, smoking, and laryngeal carcinoma. Arch Environ Health. 1975 Oct;30(10):517–519. doi: 10.1080/00039896.1975.10666767. [DOI] [PubMed] [Google Scholar]
  16. Soskolne C. L., Zeighami E. A., Hanis N. M., Kupper L. L., Herrmann N., Amsel J., Mausner J. S., Stellman J. M. Laryngeal cancer and occupational exposure to sulfuric acid. Am J Epidemiol. 1984 Sep;120(3):358–369. doi: 10.1093/oxfordjournals.aje.a113900. [DOI] [PubMed] [Google Scholar]
  17. Steenland K., Schnorr T., Beaumont J., Halperin W., Bloom T. Incidence of laryngeal cancer and exposure to acid mists. Br J Ind Med. 1988 Nov;45(11):766–776. doi: 10.1136/oem.45.11.766. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Stell P. M., McGill T. Asbestos and laryngeal carcinoma. Lancet. 1973 Aug 25;2(7826):416–417. doi: 10.1016/s0140-6736(73)92275-7. [DOI] [PubMed] [Google Scholar]

Articles from British Journal of Industrial Medicine are provided here courtesy of BMJ Publishing Group

RESOURCES