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. 1980 Mar;64(3):170–174. doi: 10.1136/bjo.64.3.170

Bilateral necrotising scleritis with marginal corneal ulceration after cataract surgery in a patient with vasculitis.

S E Bloomfield, C G Becker, C L Christian, J S Nauheim
PMCID: PMC1039381  PMID: 7387949

Abstract

The onset of bilateral necrotising scleritis and marginal corneal ulceration after cataract surgery are described in a patient with diffuse vasculitis syndrome. The finding of immune complexes in this patient's tissue biopsy suggests that they are the cause of a localised primary vasculitis triggered by surgical inflammation. Clinically, this patient's marginal corneal ulceration preceded the scleral necrosis. A past history of orbital inflammation may have been due to a posterior scleritis. The corneal ulcerations responded to conjunctival debridement and steroids. The scleral necrosis was unresponsive to the 2 anti-inflammatory preparations tried, and the patient eventually went into remission while off all treatment.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BERTELSEN T. I. Acute sclerotenonitis and ocular myositis complicated by papillitis, retinal detachment and glaucoma. Acta Ophthalmol (Copenh) 1960;38:136–152. doi: 10.1111/j.1755-3768.1960.tb00191.x. [DOI] [PubMed] [Google Scholar]
  2. Ferry A. P., Leopold I. H. Marginal (ring) corneal ulcer as presenting manifestation of Wegener's granuloma. A clinicopathologic study. Trans Am Acad Ophthalmol Otolaryngol. 1970 Nov-Dec;74(6):1276–1282. [PubMed] [Google Scholar]
  3. Henson P. M., Oades Z. G. Stimulation of human neutrophils by soluble and insoluble immunoglobulin aggregates. Secretion of granule constituents and increased oxidation of glucose. J Clin Invest. 1975 Oct;56(4):1053–1061. doi: 10.1172/JCI108152. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Jampol L. M., West C., Goldberg M. F. Therapy of scleritis with cytotoxic agents. Am J Ophthalmol. 1978 Aug;86(2):266–271. doi: 10.1016/s0002-9394(14)76823-0. [DOI] [PubMed] [Google Scholar]
  5. Sergent J. S., Christian C. L. Necrotizing vasculitis after acute serous otitis media. Ann Intern Med. 1974 Aug;81(2):195–199. doi: 10.7326/0003-4819-81-2-195. [DOI] [PubMed] [Google Scholar]
  6. Watson P. G., Hayreh S. S. Scleritis and episcleritis. Br J Ophthalmol. 1976 Mar;60(3):163–191. doi: 10.1136/bjo.60.3.163. [DOI] [PMC free article] [PubMed] [Google Scholar]

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