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. 1981 Feb;65(2):133–137. doi: 10.1136/bjo.65.2.133

Ocular lesions in the blue rubber bleb naevus syndrome.

J L Crompton, D Taylor
PMCID: PMC1039442  PMID: 7459316

Abstract

Investigations of a neonate presenting with multiple pleomorphic vascular skin lesions enabled a clinical and histological diagnosis of blue rubber bleb naevus syndrome to be made. This child had lesions in the conjunctiva, iris, and retina, associated with local haemorrhages at the time of birth. All the lesions regressed spontaneously, and a conservative approach to management of the ocular lesions in this syndrome is therefore suggested.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BURKE E. C., WINKELMANN R. K., STRICKLAND M. K. DISSEMINATED HEMANGIOMATOSIS. THE NEWBORN WITH CENTRAL NERVOUS SYSTEM INVOLVEMENT. Am J Dis Child. 1964 Oct;108:418–424. [PubMed] [Google Scholar]
  2. Colvard D. M., Robertson D. M., Trautmann J. C. Cavernous hemangioma of the retina. Arch Ophthalmol. 1978 Nov;96(11):2042–2044. doi: 10.1001/archopht.1978.03910060430006. [DOI] [PubMed] [Google Scholar]
  3. FINE R. M., DERBES V. J., CLARK W. H., Jr Blue rubber bleb nevus. Arch Dermatol. 1961 Nov;84:802–805. doi: 10.1001/archderm.1961.01580170096013. [DOI] [PubMed] [Google Scholar]
  4. Fretzin D. F., Potter B. Blue rubber bleb nevus. Arch Intern Med. 1965 Dec;116(6):924–929. [PubMed] [Google Scholar]
  5. Gass J. D. Cavernous hemangioma of the retina. A neuro-oculo-cutaneous syndrome. Am J Ophthalmol. 1971 Apr;71(4):799–814. doi: 10.1016/0002-9394(71)90245-5. [DOI] [PubMed] [Google Scholar]
  6. Hoffman T., Chasko S., Safai B. Association of blue rubber bleb nevus syndrome with chronic lymphocytic leukemia and hypernephroma. Johns Hopkins Med J. 1978 Mar;142(3):91–94. [PubMed] [Google Scholar]
  7. Morris S. J., Kaplan S. R., Ballan K., Tedesco F. J. Blue rubber-bleb nevus syndrome. JAMA. 1978 May 5;239(18):1887–1887. [PubMed] [Google Scholar]
  8. RICE J. S., FISCHER D. S. Blue rubber-bleb nevus syndrome. Generalized cavernous hemangiomatosis or venous hamartoma with medulloblastoma of the cerebellum: case report and review of the literature. Arch Dermatol. 1962 Oct;86:503–511. doi: 10.1001/archderm.1962.01590100117021. [DOI] [PubMed] [Google Scholar]
  9. SHEPHERD J. A. Angiomatous conditions of the gastro-intestinal tract. Br J Surg. 1953 Mar;40(163):409–421. doi: 10.1002/bjs.18004016302. [DOI] [PubMed] [Google Scholar]
  10. Sakurane H. F., Sugai T., Saito T. The association of blue rubber bleb nevus and Maffucci's syndrome. Arch Dermatol. 1967 Jan;95(1):28–36. [PubMed] [Google Scholar]
  11. WOOD M. W., WHITE R. J., KERNOHAN J. W. Cavernous hemangiomatosis involving the brain, spinal cord, heart, skin and kidney: report of case. Proc Staff Meet Mayo Clin. 1957 May 15;32(10):249–254. [PubMed] [Google Scholar]
  12. Walshe M. M., Evans C. D., Warin R. P. Blue rubber bleb naevus. Br Med J. 1966 Oct 15;2(5519):931–932. doi: 10.1136/bmj.2.5519.931. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Waybright E. A., Selhorst J. B., Rosenblum W. I., Suter C. G. Blue rubber bleb nevus syndrome with CNS involvement and thrombosis of a vein of galen malformation. Ann Neurol. 1978 May;3(5):464–467. doi: 10.1002/ana.410030522. [DOI] [PubMed] [Google Scholar]

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