Abstract
We reviewed the clinical features, natural history and visual prognosis of 26 patients with histologically confirmed sarcoidosis. Compatible chest x-ray changes were found in 75% of patients. Periphlebitis was the commonest fundus feature. Disc changes were seen in a substantial number of patients, and the condition can present as unilateral disc oedema. The disease seems primarily to involve equatorial retinal veins, and occlusions of a hemisphere branch vein or central retinal vein did not occur. Changes in the subretinal pigment epithelium were noted in a substantial number of patients but did not produce visual morbidity, and these patients seemed to have less florid periphlebitis than others. The disease has a low visual morbidity unless neovascularisation develops; the treatment of this remains controversial.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Chumbley L. C., Kearns T. P. Retinopathy of sarcoidosis. Am J Ophthalmol. 1972 Jan;73(1):123–131. doi: 10.1016/0002-9394(72)90314-5. [DOI] [PubMed] [Google Scholar]
- FRANCESCHETTI A., BABEL J. La choriorétinite en taches de bougie, manifestation de la maladie de Besnier-Boeck. Ophthalmologica. 1949 Oct-Nov;118(4-5):701–710. doi: 10.1159/000300769. [DOI] [PubMed] [Google Scholar]
- GOULD H., KAUFMAN H. E. Sarcoid of the fundus. Arch Ophthalmol. 1961 Mar;65:453–456. doi: 10.1001/archopht.1961.01840020455023. [DOI] [PubMed] [Google Scholar]
- Gass J. D., Olson C. L. Sarcoidosis with optic nerve and retinal involvement. Arch Ophthalmol. 1976 Jun;94(6):945–950. doi: 10.1001/archopht.1976.03910030475008. [DOI] [PubMed] [Google Scholar]
- Hart W. M., Jr, Burde R. M. Optic disk edema in sarcoidosis. Am J Ophthalmol. 1979 Oct;88(4):769–771. doi: 10.1016/0002-9394(79)90682-2. [DOI] [PubMed] [Google Scholar]
- Henkind P. Ocular neovascularization. The Krill memorial lecture. Am J Ophthalmol. 1978 Mar;85(3):287–301. [PubMed] [Google Scholar]
- James D. G., Neville E., Langley D. A. Ocular sarcoidosis. Trans Ophthalmol Soc U K. 1976 Apr;96(1):133–139. [PubMed] [Google Scholar]
- James D. G., Zatouroff M. A., Trowell J., Rose F. C. Papilloedema in sarcoidosis. Br J Ophthalmol. 1967 Aug;51(8):526–529. doi: 10.1136/bjo.51.8.526. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LAVAL J. Ocular sarcoidosis. Am J Ophthalmol. 1952 Apr;35(4):551–554. doi: 10.1016/0002-9394(52)91323-8. [DOI] [PubMed] [Google Scholar]
- Lyle T. K., Wybar K. RETINAL VASCULITIS. Br J Ophthalmol. 1961 Dec;45(12):778–788. doi: 10.1136/bjo.45.12.778. [DOI] [PMC free article] [PubMed] [Google Scholar]
- O'Day J., Shilling J. S., Ffytche T. J. Retinal vasculitis. Trans Ophthalmol Soc U K. 1979 Apr;99(1):163–166. [PubMed] [Google Scholar]
- Obenauf C. D., Shaw H. E., Sydnor C. F., Klintworth G. K. Sarcoidosis and its ophthalmic manifestations. Am J Ophthalmol. 1978 Nov;86(5):648–655. doi: 10.1016/0002-9394(78)90184-8. [DOI] [PubMed] [Google Scholar]
- Ryan S. J., Maumenee A. E. Birdshot retinochoroidopathy. Am J Ophthalmol. 1980 Jan;89(1):31–45. doi: 10.1016/0002-9394(80)90226-3. [DOI] [PubMed] [Google Scholar]
- Sanders M. D., Shilling J. S. Retinal, choroidal, and optic disc involvement in sarcoidosis. Trans Ophthalmol Soc U K. 1976 Apr;96(1):140–144. [PubMed] [Google Scholar]
- Weinreb R. N., Kimura S. J. Uveitis associated with sarcoidosis and angiotensin converting enzyme. Am J Ophthalmol. 1980 Feb;89(2):180–185. doi: 10.1016/0002-9394(80)90109-9. [DOI] [PubMed] [Google Scholar]