Skip to main content
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1981 Jul;65(7):446–451. doi: 10.1136/bjo.65.7.446

Acute shallowing of the anterior chamber.

R Mapstone
PMCID: PMC1039547  PMID: 6455153

Abstract

In aging eyes phenylephrine drops have no significant effect on the depth of the anterior chamber, whereas pilocarpine drops produce a significant shallowing. If both drugs are instilled simultaneously, a significantly greater decrease in anterior chamber depth occurs. The effect is seen in normal, glaucomatous, and hypertensive eyes, and in eyes with shallow anterior chambers. It did not occur in eyes that had had an iridectomy. During the course of a positive provocative test an acute reduction in anterior depth occurs which is reversed when the angle opens and pressure returns to normal levels. It is concluded that the depth of the anterior chamber is not a static dimension but that changes can occur which are rapid and transient. The mechanism of shallowing and deepening depends on an increase or a decrease in the pupil block force. It is a necessary consequence too that eyes with nonshallow anterior chambers can get closed-angle glaucoma and that this possibility cannot be detected by a conventional gonioscopic approach.

Full text

PDF
449

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abramson D. H., Chang S., Coleman J. Pilocarpine therapy in glaucoma: effects on anterior chamber depth and lens thickness in patients receiving long-term therapy. Arch Ophthalmol. 1976 Jun;94(6):914–918. doi: 10.1001/archopht.1976.03910030454002. [DOI] [PubMed] [Google Scholar]
  2. Abramson D. H., Coleman D. J., Forbes M., Franzen L. A. Pilocarpine. Effect on the anterior chamber and lens thickness. Arch Ophthalmol. 1972 Jun;87(6):615–620. doi: 10.1001/archopht.1972.01000020617001. [DOI] [PubMed] [Google Scholar]
  3. Fontana S. T., Brubaker R. F. Volume and depth of the anterior chamber in the normal aging human eye. Arch Ophthalmol. 1980 Oct;98(10):1803–1808. doi: 10.1001/archopht.1980.01020040655013. [DOI] [PubMed] [Google Scholar]
  4. François J., Goes F. Ultrasonographic study of the effect of different miotics on the eye components. Ophthalmologica. 1977;175(6):328–338. doi: 10.1159/000308677. [DOI] [PubMed] [Google Scholar]
  5. Gerhard J. P., Flament J., Risse J. F. Les modifications biométriques du globe dans la chirurgie choriorétinienne par la méthode d'indentation selon Lincoff. Mod Probl Ophthalmol. 1977;18:54–56. [PubMed] [Google Scholar]
  6. Lowe R. F. ACUTE ANGLE-CLOSURE GLAUCOMA: THE SECOND EYE: AN ANALYSIS OF 200 CASES. Br J Ophthalmol. 1962 Nov;46(11):641–650. doi: 10.1136/bjo.46.11.641. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Lowe R. F. Aetiology of the anatomical basis for primary angle-closure glaucoma. Biometrical comparisons between normal eyes and eyes with primary angle-closure glaucoma. Br J Ophthalmol. 1970 Mar;54(3):161–169. doi: 10.1136/bjo.54.3.161. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Mapstone R. Closed-angle glaucoma. Experimental results. Br J Ophthalmol. 1974 Jan;58(1):41–45. doi: 10.1136/bjo.58.1.41. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Mapstone R. Forces determining pupil size. Exp Eye Res. 1970 Jul;10(1):47–52. doi: 10.1016/s0014-4835(70)80007-0. [DOI] [PubMed] [Google Scholar]
  10. Mapstone R. Mechanics of pupil block. Br J Ophthalmol. 1968 Jan;52(1):19–25. doi: 10.1136/bjo.52.1.19. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Mensher J. H. Anterior chamber depth alteration after retinal photocoagulation. Arch Ophthalmol. 1977 Jan;95(1):113–116. doi: 10.1001/archopht.1977.04450010113011. [DOI] [PubMed] [Google Scholar]
  12. Phelps C. D. Angle-closure glaucoma secondary to ciliary body swelling. Arch Ophthalmol. 1974 Oct;92(4):287–290. doi: 10.1001/archopht.1974.01010010297004. [DOI] [PubMed] [Google Scholar]
  13. Poinoosawmy D., Nagasubramanian S., Brown N. A. Effect of pilocarpine on visual acuity and on the dimensions of the cornea and anterior chamber. Br J Ophthalmol. 1976 Oct;60(10):676–679. doi: 10.1136/bjo.60.10.676. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. ROSENGREN B. The etiology of acute glaucoma. Am J Ophthalmol. 1953 Apr;36(4):488–492. doi: 10.1016/0002-9394(53)90561-3. [DOI] [PubMed] [Google Scholar]
  15. Schwartz A. L., Anderson D. R. Malignant glaucoma" in an eye with no antecedent operation or miotics. Arch Ophthalmol. 1975 May;93(5):379–381. doi: 10.1001/archopht.1975.01010020391015. [DOI] [PubMed] [Google Scholar]
  16. Sears M. L., Neufeld A. H. Editorial: Adrenergic modulation of the outflow of aqueous humor. Invest Ophthalmol. 1975 Feb;14(2):83–86. [PubMed] [Google Scholar]
  17. Wilkie J., Drance S. M., Schulzer M. The effects of miotics on anterior-chamber depth. Am J Ophthalmol. 1969 Jul;68(1):78–83. doi: 10.1016/0002-9394(69)94936-8. [DOI] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES