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. 1984 Mar;68(3):192–195. doi: 10.1136/bjo.68.3.192

Pharmacokinetics of oral acyclovir (Zovirax) in the eye.

S O Hung, A Patterson, P J Rees
PMCID: PMC1040285  PMID: 6696872

Abstract

Patients due for cataract extraction received 5 doses of 400 mg acyclovir (Zovirax) orally during the 24 hours prior to surgery. Aqueous humour levels of acyclovir (mean 3.26 microM) were well above the normal ED50 range for herpes simplex virus type 1, and showed a significant correlation with plasma concentrations (mean 8.74 microM). There was also a correlation between the age of the patient and the concentration of acyclovir in the plasma. Oral acyclovir was well tolerated.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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