Skip to main content
PMC home page
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1984 Oct;68(10):746–749. doi: 10.1136/bjo.68.10.746

T-lymphocyte subpopulations in uveitis.

P I Murray, W J Dinning, A H Rahi
PMCID: PMC1040458  PMID: 6236843

Abstract

Following an inconclusive study of differential lymphocyte counts in uveitis in which the peripheral blood was examined only once in the course of each case a longitudinal study has been carried out in patients with acute anterior uveitis. Venous blood lymphocytes were examined at intervals throughout the course of the illness, from presentation until six months later. No changes in E-rosetting T cells or total lymphocyte values have been found, nor any variations from normal in the helper (OKT4)/suppressor (OKT8) T-cell ratio. Random studies performed in a sample of patients with heterochromic cyclitis have also failed to reveal consistent abnormalities in peripheral blood lymphocyte parameters.

Full text

PDF
748

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abdou N. I., Sagawa A., Pascual E., Hebert J., Sadeghee S. Suppressor T-cell abnormality in idiopathic systemic lupus erythematosus. Clin Immunol Immunopathol. 1976 Sep;6(2):192–199. doi: 10.1016/0090-1229(76)90110-0. [DOI] [PubMed] [Google Scholar]
  2. Byrom N. A., Brown J. J., Davies D. L., Fraser R., Leckie B., Lever A. F., Morton J. J. T and B lymphocytes in patients with acute anterior uveitis and ankylosing spondylitis, and in their household contacts. Lancet. 1979 Sep 22;2(8143):601–603. doi: 10.1016/s0140-6736(79)91664-7. [DOI] [PubMed] [Google Scholar]
  3. Dernouchamps J. P., Vaerman J. P., Michiels J., Masson P. L. Immune complexes in the aqueous humor and serum. Am J Ophthalmol. 1977 Jul;84(1):24–31. doi: 10.1016/0002-9394(77)90319-1. [DOI] [PubMed] [Google Scholar]
  4. Frazer I. H., Mackay I. R. T lymphocyte subpopulations defined by two sets of monoclonal antibodies in chronic active hepatitis and systemic lupus erythematosus. Clin Exp Immunol. 1982 Oct;50(1):107–114. [PMC free article] [PubMed] [Google Scholar]
  5. Hall J. M., Pribnow J. F. Fc and complement receptor lymphocytes in the ocular tissues of rabbits immunized intravitreally with ovalbumin. Invest Ophthalmol Vis Sci. 1983 Feb;24(2):192–195. [PubMed] [Google Scholar]
  6. Hall J. M., Pribnow J. F. Fc and complement receptor lymphocytes in the ocular tissues of rabbits immunized intravitreally with ovalbumin. Invest Ophthalmol Vis Sci. 1983 Feb;24(2):192–195. [PubMed] [Google Scholar]
  7. Hammer H., Olah M. Hypersensitivity towards alpha-crystalline in the heterochromia syndrome. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1975 Oct 17;197(1):61–66. doi: 10.1007/BF00506642. [DOI] [PubMed] [Google Scholar]
  8. Heredia C. D., Vich J. M., Huguet J., García-Calderón J. V., García-Calderón P. A. Altered cellular immunity and suppressor cell activity in patients with primary retinitis pigmentosa. Br J Ophthalmol. 1981 Dec;65(12):850–854. doi: 10.1136/bjo.65.12.850. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Kahn L. S., Schlaegel T. F., Jr, Weber J. C., Biegel A. Serum immunoglobulins and uveitis. Arch Ophthalmol. 1983 Mar;101(3):458–459. doi: 10.1001/archopht.1983.01040010458025. [DOI] [PubMed] [Google Scholar]
  10. Lim S. D., Haw C. R., Kim N. I., Fusaro R. M. Abnormalities of T-cell subsets in Behçet's syndrome. Arch Dermatol. 1983 Apr;119(4):307–310. [PubMed] [Google Scholar]
  11. Murray P. I., Rahi A. H. Effect of temperature and storage on lymphocyte subpopulations. Lancet. 1983 Dec 10;2(8363):1373–1374. doi: 10.1016/s0140-6736(83)91141-8. [DOI] [PubMed] [Google Scholar]
  12. Murray P. I., Rahi A. H. Pathogenesis of Mooren's ulcer: some new concepts. Br J Ophthalmol. 1984 Mar;68(3):182–187. doi: 10.1136/bjo.68.3.182. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Nussenblatt R. B., Cevario S. J., Gery I. Altered suppressor-cell activities in uveitis. Lancet. 1980 Oct 4;2(8197):722–724. doi: 10.1016/s0140-6736(80)91938-8. [DOI] [PubMed] [Google Scholar]
  14. Nussenblatt R. B., Salinas-Carmona M., Leake W., Scher I. T lymphocyte subsets in uveitis. Am J Ophthalmol. 1983 May;95(5):614–621. doi: 10.1016/0002-9394(83)90379-3. [DOI] [PubMed] [Google Scholar]
  15. Ozyazgan Y., Rahi A., Dinning W., Carvalho G. Differential lymphocyte count in eye disease. A u-turn in laboratory investigation. Trans Ophthalmol Soc U K. 1982 Apr;102(Pt 1):171–173. [PubMed] [Google Scholar]
  16. Rahi A. H., Holborow E. J., Perkins E. S., Gungen Y. Y., Dinning W. J. Immunological investigations in uveitis. Trans Ophthalmol Soc U K. 1976 Apr;96(1):113–122. [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES