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. 1985 Sep;69(9):668–672. doi: 10.1136/bjo.69.9.668

Effects of topical indomethacin pretreatment on argon laser trabeculoplasty: a randomised, double-masked study on black South Africans.

Y A Gelfand, M Wolpert
PMCID: PMC1040708  PMID: 3899165

Abstract

This randomised, double-masked study on 45 black South Africans compares the effect of topical indomethacin pretreatment with that of placebo on the immediate postoperative increase or reduction in intraocular pressure one week and one month after argon laser trabeculoplasty. There was no significant difference in the incidence and the magnitude of the immediate postoperative intraocular pressure increase between the two groups, though they occurred significantly later in the indomethacin-treated group (p less than 0.01). Although no effect of indomethacin pretreatment on the intraocular pressure reduction was evident after one week, a significant adverse effect of the drug was demonstrated after one month (p less than 0.01).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bhattacherjee P., Eakins K. E. A comparison of the inhibitory activity of compounds on ocular prostaglandin biosynthesis. Invest Ophthalmol. 1974 Dec;13(12):967–972. [PubMed] [Google Scholar]
  2. Bhattacherjee P., Eakins K. E. Inhibition of the prostaglandin synthetase systems in ocular tissues by indomethacin. Br J Pharmacol. 1974 Feb;50(2):227–230. doi: 10.1111/j.1476-5381.1974.tb08565.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bito L. Z. Absorptive transport of prostaglandins from intraocular fluids to blood: a review of recent findings. Exp Eye Res. 1973 Aug 10;16(4):299–306. doi: 10.1016/0014-4835(73)90095-x. [DOI] [PubMed] [Google Scholar]
  4. Conquet P., Plazonnet B., Le Douarec J. C. Arachidonic acid-induced elevation of intraocular pressure and anti-inflammatory agents. Invest Ophthalmol. 1975 Oct;14(10):772–775. [PubMed] [Google Scholar]
  5. Davidson S. I., Akingbehin T. Compliance in ophthalmology. Trans Ophthalmol Soc U K. 1980 Jul;100(Pt 2):286–290. [PubMed] [Google Scholar]
  6. Eakins K. E. Prostaglandin and non-prostaglandin mediated breeakdown of the blood-aqueous barrier. Exp Eye Res. 1977;25 (Suppl):483–498. doi: 10.1016/s0014-4835(77)80043-2. [DOI] [PubMed] [Google Scholar]
  7. Hanna C., Sharp J. D. Ocular absorption of indomethacin by the rabbit. Arch Ophthalmol. 1972 Aug;88(2):196–198. doi: 10.1001/archopht.1972.01000030198012. [DOI] [PubMed] [Google Scholar]
  8. Pace-Asciak C., Cole S. Inhibitors of prostaglandin catabolism. I. Differential sensitivity of 9-PGDH, 13-PGR and 15-PGDH to low concentrations of indomethacin. Experientia. 1975 Feb 15;31(2):143–145. doi: 10.1007/BF01990669. [DOI] [PubMed] [Google Scholar]
  9. Pollack I. P., Robin A. L. Argon laser trabeculoplasty: its effect on medical control of open-angle glaucoma. Ophthalmic Surg. 1982 Aug;13(8):637–643. [PubMed] [Google Scholar]
  10. Rodrigues M. M., Spaeth G. L., Donohoo P. Electron microscopy of argon laser therapy in phakic open-angle glaucoma. Ophthalmology. 1982 Mar;89(3):198–210. doi: 10.1016/s0161-6420(82)34806-x. [DOI] [PubMed] [Google Scholar]
  11. Ruderman J. M., Zweig K. O., Wilensky J. T., Weinreb R. N. Effects of corticosteroid pretreatment on argon laser trabeculoplasty. Am J Ophthalmol. 1983 Jul;96(1):84–89. doi: 10.1016/0002-9394(83)90458-0. [DOI] [PubMed] [Google Scholar]
  12. Schwartz A. L., Whitten M. E., Bleiman B., Martin D. Argon laser trabecular surgery in uncontrolled phakic open angle glaucoma. Ophthalmology. 1981 Mar;88(3):203–212. doi: 10.1016/s0161-6420(81)35048-9. [DOI] [PubMed] [Google Scholar]
  13. Thomas J. V., Simmons R. J., Belcher C. D., 3rd Argon laser trabeculoplasty in the presurgical glaucoma patient. Ophthalmology. 1982 Mar;89(3):187–197. doi: 10.1016/s0161-6420(82)34807-1. [DOI] [PubMed] [Google Scholar]
  14. Unger W. G., Cole D. F., Bass M. S. Prostaglandin and neurogenically mediated ocular response to laser irradiation of the rabbit iris. Exp Eye Res. 1977 Sep;25(3):209–220. doi: 10.1016/0014-4835(77)90088-4. [DOI] [PubMed] [Google Scholar]
  15. Weinreb R. N., Ruderman J., Juster R., Zweig K. Immediate intraocular pressure response to argon laser trabeculoplasty. Am J Ophthalmol. 1983 Mar;95(3):279–286. doi: 10.1016/s0002-9394(14)78294-7. [DOI] [PubMed] [Google Scholar]
  16. Wilensky J. T., Jampol L. M. Laser therapy for open angle glaucoma. Ophthalmology. 1981 Mar;88(3):213–217. doi: 10.1016/s0161-6420(81)35047-7. [DOI] [PubMed] [Google Scholar]
  17. Wise J. B. Long-term control of adult open angle glaucoma by argon laser treatment. Ophthalmology. 1981 Mar;88(3):197–202. doi: 10.1016/s0161-6420(81)35049-0. [DOI] [PubMed] [Google Scholar]
  18. Wise J. B., Witter S. L. Argon laser therapy for open-angle glaucoma. A pilot study. Arch Ophthalmol. 1979 Feb;97(2):319–322. doi: 10.1001/archopht.1979.01020010165017. [DOI] [PubMed] [Google Scholar]

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