Skip to main content
PMC home page
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1988 Sep;72(9):646–659. doi: 10.1136/bjo.72.9.646

Birdshot chorioretinopathy: clinical characteristics and evolution.

H A Priem 1, J A Oosterhuis 1
PMCID: PMC1041551  PMID: 2460128

Abstract

During the period 1980-6 102 patients from 14 European eye clinics were diagnosed as having birdshot chorioretinopathy (BSCR). All were Caucasian, and the series consisted of 47 men and 55 women, with a mean age of 52.5 years. The major findings in this rare disorder concern the ocular fundus. Most marked are the patterned distribution of depigmented spots without hyperpigmentation, radiation from the optic disc in association with vitritis, retinal vasculopathy with frequent cystoid macular oedema, and involvement of the optic nerve head. The distribution and appearance of the lesions suggest that they are related to the major choroidal veins. Complications of the disease were epiretinal membranes, retinal neovascularisation, recurrent vitreous haemorrhage, subretinal neovascular membranes occurring both in the juxtapapillary and macular regions, and optic atrophy. The medical history was not contributary. HLA testing showed very strong disease association with HLA A29 (95.8%). The evidence suggests that it is a single disease entity rather than a group of disorders because of the remarkable similarity in the ophthalmological appearance and the clinical course, combined with the exceptionally high association with HLA A29.

Full text

PDF
650

Images in this article

657Image
on p.657
649Image
on p.649
646Image
on p.646
650Image
on p.650
651Image
on p.651
651Image
on p.651
652Image
on p.652
652Image
on p.652
653Image
on p.653
654Image
on p.654
654Image
on p.654
654Image
on p.654

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amalric P., Cuq G. Une forme très particulière de choriorétinopathie en grains de riz. Bull Soc Ophtalmol Fr. 1981 Jan;81(1):131–134. [PubMed] [Google Scholar]
  2. Brockhurst R. J., Schepens C. L. Uveitis. IV. Peripheral uveitis: the complications of retinal detachment. Arch Ophthalmol. 1968 Dec;80(6):747–753. doi: 10.1001/archopht.1968.00980050749013. [DOI] [PubMed] [Google Scholar]
  3. Brucker A. J., Deglin E. A., Bene C., Hoffman M. E. Subretinal choroidal neovascularization in birdshot retinochoroidopathy. Am J Ophthalmol. 1985 Jan 15;99(1):40–44. doi: 10.1016/s0002-9394(14)75864-7. [DOI] [PubMed] [Google Scholar]
  4. De Laey J. J., Priem H. Birdshot chorioretinopathy: an etiological problem. Bull Soc Belge Ophtalmol. 1981;193:131–136. [PubMed] [Google Scholar]
  5. FRANCESCHETTI A., BABEL J. La choriorétinite en taches de bougie, manifestation de la maladie de Besnier-Boeck. Ophthalmologica. 1949 Oct-Nov;118(4-5):701–710. doi: 10.1159/000300769. [DOI] [PubMed] [Google Scholar]
  6. Felder K. S., Brockhurst R. J. Neovascular fundus abnormalities in peripheral uveitis. Arch Ophthalmol. 1982 May;100(5):750–754. doi: 10.1001/archopht.1982.01030030754006. [DOI] [PubMed] [Google Scholar]
  7. Fuerst D. J., Tessler H. H., Fishman G. A., Yokoyama M. M., Wyhinny G. J., Vygantas C. M. Birdshot retinochoroidopathy. Arch Ophthalmol. 1984 Feb;102(2):214–219. doi: 10.1001/archopht.1984.01040030164018. [DOI] [PubMed] [Google Scholar]
  8. Gass J. D. Vitiliginous chorioretinitis. Arch Ophthalmol. 1981 Oct;99(10):1778–1787. doi: 10.1001/archopht.1981.03930020652006. [DOI] [PubMed] [Google Scholar]
  9. Henkind P. Ocular neovascularization. The Krill memorial lecture. Am J Ophthalmol. 1978 Mar;85(3):287–301. [PubMed] [Google Scholar]
  10. Kaplan H. J., Aaberg T. M. Birdshot retinochoroidopathy. Am J Ophthalmol. 1980 Dec;90(6):773–782. doi: 10.1016/s0002-9394(14)75192-x. [DOI] [PubMed] [Google Scholar]
  11. Katsnel'son L. A., Kaliberdina A. F. Birdshot-khorioretinopatiia--novyi klinicheskii sindrom. Vestn Oftalmol. 1984 Sep-Oct;(5):49–51. [PubMed] [Google Scholar]
  12. Laroche L., Saraux H., Quentel G., Le Hoang P. Bird-shot chorioretinopathy après décollement de rétine: origine auto-immune probable. Bull Soc Ophtalmol Fr. 1983 Nov;83(11):1245–1247. [PubMed] [Google Scholar]
  13. Nussenblatt R. B., Mittal K. K., Ryan S., Green W. R., Maumenee A. E. Birdshot retinochoroidopathy associated with HLA-A29 antigen and immune responsiveness to retinal S-antigen. Am J Ophthalmol. 1982 Aug;94(2):147–158. doi: 10.1016/0002-9394(82)90069-1. [DOI] [PubMed] [Google Scholar]
  14. Oosterhuis J. A., Baarsma G. S., Polak B. C. Birdshot chorioretinopathy--vitiliginous chorioretinitis. Int Ophthalmol. 1982 Nov;5(3):137–144. doi: 10.1007/BF00149142. [DOI] [PubMed] [Google Scholar]
  15. Rosenberg P. R., Noble K. G., Walsh J. B., Carr R. E. Birdshot retinochoroidopathy. Ophthalmology. 1984 Mar;91(3):304–306. doi: 10.1016/s0161-6420(84)34301-9. [DOI] [PubMed] [Google Scholar]
  16. Ryan S. J., Maumenee A. E. Birdshot retinochoroidopathy. Am J Ophthalmol. 1980 Jan;89(1):31–45. doi: 10.1016/0002-9394(80)90226-3. [DOI] [PubMed] [Google Scholar]
  17. Salvanet-Bouccara A., Forestier F. Choriorétinopathie de type birdshot. J Fr Ophtalmol. 1983;6(8-9):671–676. [PubMed] [Google Scholar]
  18. Soubrane G., Coscas G., Binaghi M., Amalric P., Bernard J. A. Birdshot retinochoroidopathy and subretinal new vessels. Br J Ophthalmol. 1983 Jul;67(7):461–467. doi: 10.1136/bjo.67.7.461. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Wagoner M. D., Albert D. M., Lerner A. B., Kirkwood J., Forget B. M., Nordlund J. J. New observations on vitiligo and ocular disease. Am J Ophthalmol. 1983 Jul;96(1):16–26. doi: 10.1016/0002-9394(83)90450-6. [DOI] [PubMed] [Google Scholar]
  20. Yoshioka T., Yoshioka H., Tanaka F. [Birdshot retinochoroidopathy as a new ocular sign of the sarcoidosis]. Nippon Ganka Gakkai Zasshi. 1983;87(4):283–288. [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES