Abstract
We examined 241 leprosy patients and 135 age-matched healthy controls in central South Korea, measuring intraocular pressure in the supine and the upright positions and measuring the size of the pupils in darkness as an indication of ocular autonomic dysfunction. The mean intraocular pressure was significantly lower in the patients and the mean size of pupils was significantly smaller in the patients than in the controls. However, there was no correlation between pupil size and intraocular pressure in our patients. Our findings show that leprosy patients have ocular autonomic dysfunction, but do not support previous speculation that this dysfunction is the primary cause for low intraocular pressure in leprosy.
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Selected References
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- Courtright P. D. Defining the magnitude of ocular complications from leprosy: problems of methodology. Int J Lepr Other Mycobact Dis. 1988 Dec;56(4):566–573. [PubMed] [Google Scholar]
- Ffytche T. J. Role of iris changes as a cause of blindness in lepromatous leprosy. Br J Ophthalmol. 1981 Apr;65(4):231–239. doi: 10.1136/bjo.65.4.231. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Krieglstein G., Langham M. E. Influence of body position on the intraocular pressure of normal and glaucomatous eyes. Ophthalmologica. 1975;171(2):132–145. doi: 10.1159/000307479. [DOI] [PubMed] [Google Scholar]
- Leonard T. J., Kerr Muir M. G., Kirkby G. R., Hitchings R. A. Ocular hypertension and posture. Br J Ophthalmol. 1983 Jun;67(6):362–366. doi: 10.1136/bjo.67.6.362. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Newcombe R. G., Duff G. R. Eyes or patients? Traps for the unwary in the statistical analysis of ophthalmological studies. Br J Ophthalmol. 1987 Sep;71(9):645–646. doi: 10.1136/bjo.71.9.645. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Slem G. Clinical studies of ocular leprosy. Am J Ophthalmol. 1971 Jan;71(1 Pt 2):431–434. doi: 10.1016/0002-9394(71)90423-5. [DOI] [PubMed] [Google Scholar]
- Williams B. I., Ledingham J. G. Significance of intraocular pressure measurement in systemic hypertension. Br J Ophthalmol. 1984 Jun;68(6):383–388. doi: 10.1136/bjo.68.6.383. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Williams B. I., Peart W. S., Letley E. Abnormal intraocular pressure control in systemic hypertension and diabetic mellitus. Br J Ophthalmol. 1980 Nov;64(11):845–851. doi: 10.1136/bjo.64.11.845. [DOI] [PMC free article] [PubMed] [Google Scholar]