Skip to main content
PMC home page
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1990 Nov;74(11):643–646. doi: 10.1136/bjo.74.11.643

Fluorosilicone oil in the treatment of retinal detachment.

C M Gremillion Jr 1, G A Peyman 1, K R Liu 1, K S Naguib 1
PMCID: PMC1042248  PMID: 2223698

Abstract

We evaluated the use of a heavier-than-water fluorinated silicone oil in the treatment of 30 selected cases of complicated retinal detachment from January 1988 to July 1989. Proliferative vitreoretinopathy grade C-2 or greater accounted for 19 cases, proliferative diabetic retinopathy with traction detachment for two cases, giant retinal tears five, ruptured globe with retinal detachment two, massive choroidal effusion with retinal detachment one, and acute retinal necrosis with retinal detachment one. Initial retinal reattachment was achieved in all cases. Complications included redetachment seven (23%), cataract six (75% of phakic patients), raised intraocular pressure four (13%), hypotony four (13%), keratopathy three (10%), uveitis-synechia formation three (10%), phthisis two (3%), choroidal haemorrhage one (3%), and vitreous haemorrhage one (3%). Postoperative visual acuities with at least six months' follow-up range from no light perception to 20/50, with seven patients (23%) 20/400 or better.

Full text

PDF
644

Images in this article

644Image
on p.644
645Image
on p.645
645Image
on p.645

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Biro G. P., Blais P. Perfluorocarbon blood substitutes. Crit Rev Oncol Hematol. 1987;6(4):311–374. doi: 10.1016/s1040-8428(87)80018-5. [DOI] [PubMed] [Google Scholar]
  2. CIBIS P. A., BECKER B., OKUN E., CANAAN S. The use of liquid silicone in retinal detachment surgery. Arch Ophthalmol. 1962 Nov;68:590–599. doi: 10.1001/archopht.1962.00960030594005. [DOI] [PubMed] [Google Scholar]
  3. Chang S. Low viscosity liquid fluorochemicals in vitreous surgery. Am J Ophthalmol. 1987 Jan 15;103(1):38–43. doi: 10.1016/s0002-9394(14)74166-2. [DOI] [PubMed] [Google Scholar]
  4. Chang S., Zimmerman N. J., Iwamoto T., Ortiz R., Faris D. Experimental vitreous replacement with perfluorotributylamine. Am J Ophthalmol. 1987 Jan 15;103(1):29–37. doi: 10.1016/s0002-9394(14)74165-0. [DOI] [PubMed] [Google Scholar]
  5. Crisp A., de Juan E., Jr, Tiedeman J. Effect of silicone oil viscosity on emulsification. Arch Ophthalmol. 1987 Apr;105(4):546–550. doi: 10.1001/archopht.1987.01060040116047. [DOI] [PubMed] [Google Scholar]
  6. Labelle P., Okun E. Ocular tolerance to liquid silicone. An experimental study. Can J Ophthalmol. 1972 Apr;7(2):199–204. [PubMed] [Google Scholar]
  7. Leaver P. K., Grey R. H., Garner A. Silicone oil injection in the treatment of massive preretinal retraction. II. Late complications in 93 eyes. Br J Ophthalmol. 1979 May;63(5):361–367. doi: 10.1136/bjo.63.5.361. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Liu K. R., Peyman G. A., Miceli M. V. Experimental evaluation of low-viscosity fluorosilicone oil as a temporary vitreous substitute. Ophthalmic Surg. 1989 Oct;20(10):720–725. [PubMed] [Google Scholar]
  9. McCuen B. W., 2nd, de Juan E., Jr, Landers M. B., 3rd, Machemer R. Silicone oil in vitreoretinal surgery. Part 2: Results and complications. Retina. 1985 Fall-Winter;5(4):198–205. doi: 10.1097/00006982-198500540-00002. [DOI] [PubMed] [Google Scholar]
  10. Miyamoto K., Refojo M. F., Tolentino F. I., Fournier G. A., Albert D. M. Fluorinated oils as experimental vitreous substitutes. Arch Ophthalmol. 1986 Jul;104(7):1053–1056. doi: 10.1001/archopht.1986.01050190111048. [DOI] [PubMed] [Google Scholar]
  11. Miyamoto K., Refojo M. F., Tolentino F. I., Fournier G. A., Albert D. M. Perfluoroether liquid as a long-term vitreous substitute. An experimental study. Retina. 1984 Fall-Winter;4(4):264–268. doi: 10.1097/00006982-198400440-00010. [DOI] [PubMed] [Google Scholar]
  12. Nabih M., Peyman G. A., Clark L. C., Jr, Hoffman R. E., Miceli M., Abou-Steit M., Tawakol M., Liu K. R. Experimental evaluation of perfluorophenanthrene as a high specific gravity vitreous substitute: a preliminary report. Ophthalmic Surg. 1989 Apr;20(4):286–293. [PubMed] [Google Scholar]
  13. Paylor R., Peyman G. A., Badri S. Effects of intravitreal injection of fluorosilicone oil after vitrectomy in the rabbit eye. Can J Ophthalmol. 1987 Aug;22(5):251–253. [PubMed] [Google Scholar]
  14. Peyman G. A., Smith R. T., Charles H. Injection of fluorosilicone oil and pars plana vitrectomy for complex retinal detachment. Can J Ophthalmol. 1987 Aug;22(5):276–278. [PubMed] [Google Scholar]
  15. Peyman G. A., Smith R. T. Use of fluorosilicone to unfold a giant retinal tear. Int Ophthalmol. 1987 Jun;10(3):149–151. doi: 10.1007/BF00139340. [DOI] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES