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. 1980 Feb;56(1):37–45. doi: 10.1136/sti.56.1.37

Chlamydial infection of the cervix in contacts of men with nongonococcal urethritis.

I A Tait, E Rees, D Hobson, R E Byng, M C Tweedie
PMCID: PMC1045724  PMID: 7370720

Abstract

An investigation of chlamydial infection in sexual contacts of patients with nongonococcal urethritis (NGU) was carried out to determine the clinical signs of infection in the cervix, and their response to chemotherapy, and the incidence of cervical infection in the presence of ectopy and oral contraception. In 202 consecutive female contacts of NGU the isolation rate of Chlamydia trachomatis was 35%. Hypertrophic ectopy and endocervical mucopus were present in 19% and 37% of chlamydia-positive patients respectively and, in all but one, resolved after treatment. Only 14% of those followed up after treatment developed yeast infections. The chlamydial isolation rate was significantly higher in patients with hypertrophic ectopy and endocervical mucopus. Cervical ectopy and oral contraceptives acted additively, each producing a significant effect on the chlamydial isolation rate in the presence of the other but not when present alone.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Burns D. C., Darougar S., Thin R. N., Lothian L., Nicol C. S. Isolation of Chlamydia from women attending a clinic for sexually transmitted disease. Br J Vener Dis. 1975 Oct;51(5):314–318. doi: 10.1136/sti.51.5.314. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Davies J. A., Rees E., Hobson D., Karayiannis P. Isolation of Chlamydia trachomatis from Bartholin's ducts. Br J Vener Dis. 1978 Dec;54(6):409–413. doi: 10.1136/sti.54.6.409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Dunlop E. M., Darougar S., Hare M. J., Treharne J. D., Dwyer R. S. Isolation of chlamydia from the urethra of a woman. Br Med J. 1972 May 13;2(5810):386–386. doi: 10.1136/bmj.2.5810.386. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Dunlop E. M., Hare M. J., Darougar S., Jones B. R., Rice N. S. Detection of Chlamydia (Bedsonia) in certain infections of man. II. Clinical study of genital tract, eye, rectum, and other sites of recovery of Chlamydia. J Infect Dis. 1969 Oct;120(4):463–470. doi: 10.1093/infdis/120.4.463. [DOI] [PubMed] [Google Scholar]
  5. Dunlop E. M., al-Hussaini M. K., Freedman A., Garland J. A., Harper I. A., Jones B. R., Race J. W., Du Toit M. S., Treharne J. D., Wright D. J. Infection by TRIC agent and other members of the Bedsonia group; with a note on Reiter's disease. 3. Genital infection and disease of the eye. Trans Ophthalmol Soc U K. 1966;86:321–334. [PubMed] [Google Scholar]
  6. Goldacre M. J., Loudon N., Watt B., Grant G., Loudon J. D., McPherson K., Vessey M. P. Epidemiology and clinical significance of cervical erosion in women attending a family planning clinic. Br Med J. 1978 Mar 25;1(6115):748–750. doi: 10.1136/bmj.1.6115.748. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hilton A. L., Richmond S. J., Milne J. D., Hindley F., Clarke S. K. Chlamydia A in the female genital tract. Br J Vener Dis. 1974 Feb;50(1):1–10. doi: 10.1136/sti.50.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Holmes K. K., Handsfield H. H., Wang S. P., Wentworth B. B., Turck M., Anderson J. B., Alexander E. R. Etiology of nongonococcal urethritis. N Engl J Med. 1975 Jun 5;292(23):1199–1205. doi: 10.1056/NEJM197506052922301. [DOI] [PubMed] [Google Scholar]
  9. Johnson F. W., Hobson D. Factors affecting the sensitivity of replicating McCoy cells in the isolation and growth of chlamydia A (TRIC agents). J Hyg (Lond) 1976 Jun;76(3):441–451. doi: 10.1017/s0022172400055376. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Nayyar K. C., O'Neill J. J., Hambling M. H., Waugh M. A. Isolation of Chlamydia trachomatis from women attending a clinic for sexually transmitted diseases. Br J Vener Dis. 1976 Dec;52(6):396–398. doi: 10.1136/sti.52.6.396. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Oriel J. D., Johnson A. L., Barlow D., Thomas B. J., Nayyar K., Reeve P. Infection of the uterine cervix with Chlamydia trachomatis. J Infect Dis. 1978 Apr;137(4):443–451. doi: 10.1093/infdis/137.4.443. [DOI] [PubMed] [Google Scholar]
  12. Oriel J. D., Powis P. A., Reeve P., Miller A., Nicol C. S. Chlamydial infections of the cervix. Br J Vener Dis. 1974 Feb;50(1):11–16. doi: 10.1136/sti.50.1.11. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Paavonen J., Saikku P., Vesterinen E., Meyer B., Vartiainen E., Saksela E. Genital chlamydial infections in patients attending a gynaecological outpatient clinic. Br J Vener Dis. 1978 Aug;54(4):257–261. doi: 10.1136/sti.54.4.257. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Richmond S. J. The isolation of Chlamydia subgroup A (Chlamydia trachomatis) in irradiated McCoy cells. Med Lab Technol. 1974 Jan;31(1):7–9. [PubMed] [Google Scholar]
  15. Schachter J. Chlamydial infections (first of three parts). N Engl J Med. 1978 Feb 23;298(8):428–435. doi: 10.1056/NEJM197802232980805. [DOI] [PubMed] [Google Scholar]
  16. Terho P. Chlamydia trachomatis in non-specific urethritis. Br J Vener Dis. 1978 Aug;54(4):251–256. doi: 10.1136/sti.54.4.251. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Wentworth B. B., Bonin P., Holmes K. K., Gutman L., Wiesner P., Alexander E. R. Isolation of viruses, bacteria and other organisms from venereal disease clinic patients: methodology and problems associated with multiple isolations. Health Lab Sci. 1973 Apr;10(2):75–81. [PubMed] [Google Scholar]

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