Skip to main content
The British Journal of Venereal Diseases logoLink to The British Journal of Venereal Diseases
. 1980 Jun;56(3):137–143. doi: 10.1136/sti.56.3.137

Ultrastructure of vascular and connective tissue changes in primary syphilis.

T Wrzolkowa, J Kozakiewicz
PMCID: PMC1045755  PMID: 7000302

Abstract

Electron microscopical studies of primary syphilitic lesions showed intensive changes in the capillaries in the form of endothelial proliferation and extensive infilitration of different cells in the surrounding connective tissue. The degenerative changes in axon terminals could explain the painless course of primary induration.

Full text

PDF
139

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Azar H. A., Pham T. D., Kurban A. K. An electron microscopic study of a syphilitic chancre. Engulfment of Treponema pallidum by plasma cells. Arch Pathol. 1970 Aug;90(2):143–150. [PubMed] [Google Scholar]
  2. Brause B. D., Roberts R. B. Attachment of virulent Treponema pallidum to human mononuclear phagocytes. Br J Vener Dis. 1978 Aug;54(4):218–224. doi: 10.1136/sti.54.4.218. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Braverman I. M., Yen A. Ultrastructure of the human dermal microcirculation. II. The capillary loops of the dermal papillae. J Invest Dermatol. 1977 Jan;68(1):44–52. doi: 10.1111/1523-1747.ep12485165. [DOI] [PubMed] [Google Scholar]
  4. Hasegawa T. Electron microscopic observations on the lesions of condyloma latum. Br J Dermatol. 1969 May;81(5):367–374. doi: 10.1111/j.1365-2133.1969.tb14000.x. [DOI] [PubMed] [Google Scholar]
  5. Metz J., Metz G. Elektronemikroskopischer nachweis von Treponema pallidum in Hautefflorescenzen der unbehandelten Lues I und I. Arch Dermatol Forsch. 1972;243(3):241–254. [PubMed] [Google Scholar]
  6. Musher D. M., Izzat N. N., Min K. W., Györkey F. In vitro phagocytosis of avirulent T. pallidum by rabbit macrophages. Acta Derm Venereol. 1972;52(5):349–352. [PubMed] [Google Scholar]
  7. Ovcinnikov N. M., Delektorskij V. V. Treponema pallidum in nerve fibres. Br J Vener Dis. 1975 Feb;51(1):10–18. doi: 10.1136/sti.51.1.10. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Sykes J. A., Miller J. N., Kalan A. J. Treponema pallidum within cells of a primary chancre from a human female. Br J Vener Dis. 1974 Feb;50(1):40–44. doi: 10.1136/sti.50.1.40. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Twomey J. J., Sharkey O., Jr, Brown J. A., Laughter A. H., Jordan P. H., Jr Cellular requirements for the mitotic response in allogeneic mixed leukocyte cultures. J Immunol. 1970 Apr;104(4):845–853. [PubMed] [Google Scholar]

Articles from British Journal of Venereal Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES