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. 1984 Jun;60(3):186–188. doi: 10.1136/sti.60.3.186

Thymus derived lymphocytes (T cells) in patients with genital warts.

K C Mohanty, R B Roy
PMCID: PMC1046297  PMID: 6610454

Abstract

Thymus derived lymphocytes (T cells) were counted in the peripheral blood of 30 patients with genital warts and in 20 healthy controls. The control group was made up of 10 healthy patients with no history of warts and 10 who had been cured of warts for at least 12 months. We found that patients with genital warts had a significantly lower number of T cells despite an adequate number of circulating lymphocytes in the peripheral blood. We therefore suggest that a functional defect of lymphocytes ("dyslymphocytosis") could be the cause of genital warts either in their primary or recurrent form. These abnormal lymphocytes return to their normal function after the disappearance of genital warts.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chretien J. H., Esswein J. G., Garagusi V. F. Decreased T cell levels in patients with warts. Arch Dermatol. 1978 Feb;114(2):213–215. [PubMed] [Google Scholar]
  2. Lee A. K., Eisinger M. Cell-mediated immunity (CMI) to human wart virus and wart-associated tissue antigens. Clin Exp Immunol. 1976 Dec;26(3):419–424. [PMC free article] [PubMed] [Google Scholar]
  3. Morison W. L. Cell-mediated immune responses in patients with warts. Br J Dermatol. 1975 Nov;93(5):553–556. doi: 10.1111/j.1365-2133.1975.tb02248.x. [DOI] [PubMed] [Google Scholar]
  4. Morrison W. L. In vitro assay of cell-mediated immunity to human wart antigen. Br J Dermatol. 1974 May;90(5):531–534. doi: 10.1111/j.1365-2133.1974.tb06448.x. [DOI] [PubMed] [Google Scholar]
  5. Smith J. L., Haegert D. B- and T-lymphocyte markers on transformed lymphocytes from mitogen-stimulated cultures of normal and CLL lymphocytes and on tonsil blasts. Clin Exp Immunol. 1974 Aug;17(4):547–560. [PMC free article] [PubMed] [Google Scholar]

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