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. 1978 Apr;54(2):81–83. doi: 10.1136/sti.54.2.81

Metronidazole and tinidazole in a single large dose for treating urogenital infections with Trichomonas vaginalis in men.

N Kawamura
PMCID: PMC1046366  PMID: 305809

Abstract

Seventy-three men with urogenital trichomonal infection were treated with a single daily dose of 1 g tinidazole or 1.5 g metronidazole. Both treatments gave satisfactory results. Wives who were also infected with Trichomonas vaginalis, were less likely to have a recurrence of the infection after their husbands had been given either drug.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ASAMI K. Bacteria-free cultivation of Trichomonas vaginalis. Kitasato Arch Exp Med. 1952 Oct;25(2):149–156. [PubMed] [Google Scholar]
  2. BEDOYA J. M., RICO L. R., RIOS G. Trichomoniasis der menschlichen Genitalien; venerische Erkrankung. II. Trichomonadenbefall bei Dirnen und Jungfrauen. Geburtshilfe Frauenheilkd. 1958 Aug;18(8):994–996. [PubMed] [Google Scholar]
  3. BEDOYA J. M., RIOS G., RICO L. R. Trichomonadenbefall der Genitalien; venerische Erkrankung. I. Ergebnisse von Untersuchungen an Ehemännern, deren Frauen an Trichomonas vaginalis leiden. Geburtshilfe Frauenheilkd. 1958 Aug;18(8):989–994. [PubMed] [Google Scholar]
  4. CATTERALL R. D., NICOL C. S. Is trichomonal infestation a veneral disease? Br Med J. 1960 Apr 16;1(5180):1177–1179. doi: 10.1136/bmj.1.5180.1177. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Campbell A. C. 24-Hour treatment of trichomoniasis with nimorazole (nitrimidazine). Br J Vener Dis. 1972 Dec;48(6):531–533. doi: 10.1136/sti.48.6.531. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Catterall R. D. Treatment of trichomonal prostatitis with metronidazole. Br J Vener Dis. 1965 Dec;41(4):302–303. doi: 10.1136/sti.41.4.302. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Csonka G. W. Trichomonal vaginitis treated with one dose of metronidazole. Br J Vener Dis. 1971 Dec;47(6):456–458. doi: 10.1136/sti.47.6.456. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Dellenbach P., Muller P. Single dose therapy of urogenital trichomoniasis with 2 grams tinidazole. Curr Med Res Opin. 1974;2(3):142–146. doi: 10.1185/03007997409113629. [DOI] [PubMed] [Google Scholar]
  9. Forsgren A., Wallin J. Trinidazole--a new preparation for Trichomonas vaginalis infections. I. Laboratory evaluation. Br J Vener Dis. 1974 Apr;50(2):146–147. doi: 10.1136/sti.50.2.146. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. HOFFMANN B., KILCZEWSKI W., MALYSZKO E. Studies on trichomoniasis in males. Br J Vener Dis. 1961 Jun;37:172–175. doi: 10.1136/sti.37.2.172. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Hayward M. J., Roy R. B. Two-day treatment of trichomoniasis in the female. Comparison of metronidazole and nimorazole. Br J Vener Dis. 1976 Feb;52(1):63–64. doi: 10.1136/sti.52.1.63. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Jones J. P. Treatment of trichomoniasis with a single dose of nimorazole (nitrimidazine). Br J Vener Dis. 1972 Dec;48(6):528–530. doi: 10.1136/sti.48.6.528. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. KEUTEL H. J. [Trichomoniasis--a parasitosis transmissible by sexual intercourse]. Hautarzt. 1959 May;10:212–216. [PubMed] [Google Scholar]
  14. Kawamura N. [Studies on Trichomonas vaginalis in the urological field. 1]. Nihon Hinyokika Gakkai Zasshi. 1969 Jan;60(1):15–24. doi: 10.5980/jpnjurol1928.60.1_15. [DOI] [PubMed] [Google Scholar]
  15. Kawamura N. [Studies on Trichomonas vaginalis in urological field. VI. Clinical efficacy of various drugs]. Nihon Hinyokika Gakkai Zasshi. 1973 Apr;64(4):281–286. doi: 10.5980/jpnjurol1928.64.4_281. [DOI] [PubMed] [Google Scholar]
  16. Kimura S. [Studies on trichomoniasis vaginalis in urological patients]. Nihon Hinyokika Gakkai Zasshi. 1965 May;56(5):455–475. doi: 10.5980/jpnjurol1928.56.5_455. [DOI] [PubMed] [Google Scholar]
  17. Morton R. S. Metronidazole in the single-dose treatment of trichomoniasis in men and women. Br J Vener Dis. 1972 Dec;48(6):525–527. doi: 10.1136/sti.48.6.525. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. PERL G., RAGAZZONI H. FURTHER STUDIES IN TREATMENT OF FEMALE AND MALE TRICHOMONIASIS WITH METRONIDAZOLE. Obstet Gynecol. 1963 Sep;22:376–381. [PubMed] [Google Scholar]
  19. PERL G., SCHAPIRA H. E., RAGAZZONI H. MALE UROGENITAL TRICHOMONIASIS. J Mt Sinai Hosp N Y. 1965 Jul-Aug;32:495–506. [PubMed] [Google Scholar]
  20. RODIN P., KING A. J., NICOL C. S., BARROW J. Flagyl in the treatment of trichomoniasis. Br J Vener Dis. 1960 Sep;36:147–151. doi: 10.1136/sti.36.3.147. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. SCHAPIRA H. E. STUDIES ON METRONIDAZOLE (FLAGYL) IN THE THERAPY OF UROGENITAL TRICHOMONIASIS IN THE MALE PATIENT. J Urol. 1965 Feb;93:303–306. doi: 10.1016/S0022-5347(17)63763-7. [DOI] [PubMed] [Google Scholar]
  22. SYLVESTRE L., BELANGER M., GALLAI Z. Urogenital trichomoniasis in the male: review of the literature and report on treatment of 37 patients by a new nitroimidazole derivative (Flagyl). Can Med Assoc J. 1960 Dec 3;83:1195–1199. [PMC free article] [PubMed] [Google Scholar]
  23. Schmör J. Single-dose treatment with tinidazole: progress in the therapy of trichomoniasis. Curr Med Res Opin. 1974;2(3):138–141. doi: 10.1185/03007997409113628. [DOI] [PubMed] [Google Scholar]
  24. Wallin J. A clinical pattern for making an immediate-presumptive diagnosis of gonococcal infection in women. Acta Derm Venereol. 1974;54(2):157–160. [PubMed] [Google Scholar]
  25. Wallin J., Forsgren A. Tinidazole--a new preparation for T. vaginalis infections. II. Clinical evaluation of treatment with a single oral dose. Br J Vener Dis. 1974 Apr;50(2):148–150. doi: 10.1136/sti.50.2.148. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Weidenbach A., Leix H. Treatment of trichomonal vaginitis with a single dose of tinidazole. Curr Med Res Opin. 1974;2(3):147–152. doi: 10.1185/03007997409113630. [DOI] [PubMed] [Google Scholar]
  27. Wood B. A., Monro A. M. Pharmacokinetics of tinidazole and metronidazole in women after single large oral doses. Br J Vener Dis. 1975 Feb;51(1):51–53. doi: 10.1136/sti.51.1.51. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Woodcock K. R. Treatment of trichomonal vaginitis with a single oral dose of metronidazole. Br J Vener Dis. 1972 Feb;48(1):65–68. doi: 10.1136/sti.48.1.65. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. YAMAMOTO H. [MALE AND FEMALE UROGENITAL TRICHOMONIASIS]. Nihon Hinyokika Gakkai Zasshi. 1963 Sep;54:891–896. [PubMed] [Google Scholar]

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