Skip to main content
PMC home page
Journal of Medical Genetics logoLink to Journal of Medical Genetics
. 1997 May;34(5):433–437. doi: 10.1136/jmg.34.5.433

Wiedemann-Rautenstrauch neonatal progeroid syndrome: report of three new patients.

H Arboleda 1, L Quintero 1, E Yunis 1
PMCID: PMC1050956  PMID: 9152846

Abstract

Wiedemann-Rautenstrauch (WR) syndrome is known as a neonatal progeroid syndrome, with only few published case reports. We describe three additional patients, two of them sibs, showing the clinical features of WR syndrome. Skeletal abnormalities are reported and assays of hormones and lipids are presented in one patient. Disturbance in bone maturation and lipid and hormone metabolism appear to be involved in this neonatal progeroid syndrome.

Full text

PDF
434

Images in this article

434Image
on p.434
435Image
on p.435

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bitoun P., Lachassine E., Sellier N., Sauvion S., Gaudelus J. The Wiedemann-Rautenstrauch neonatal progeroid syndrome: a case report and review of the literature. Clin Dysmorphol. 1995 Jul;4(3):239–245. [PubMed] [Google Scholar]
  2. Castiñeyra G., Panal M., Lopez Presas H., Goldschmidt E., Sánchez J. M. Two sibs with Wiedemann-Rautenstrauch syndrome: possibilities of prenatal diagnosis by ultrasound. J Med Genet. 1992 Jun;29(6):434–436. doi: 10.1136/jmg.29.6.434. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Devos E. A., Leroy J. G., Frijns J. P., Van den Berghe H. The Wiedemann-Rautenstrauch or neonatal progeroid syndrome. Report of a patient with consanguineous parents. Eur J Pediatr. 1981 Jul;136(3):245–248. doi: 10.1007/BF00442991. [DOI] [PubMed] [Google Scholar]
  4. Martin J. J., Ceuterick C. M., Leroy J. G., Devos E. A., Roelens J. G. The Wiedemann-Rautenstrauch or neonatal progeroid syndrome. Neuropathological study of a case. Neuropediatrics. 1984 Feb;15(1):43–48. doi: 10.1055/s-2008-1052339. [DOI] [PubMed] [Google Scholar]
  5. Obregon M. G., Bergami G. L., Giannotti A., Digilio M. C., Virgili Q., Guadagni A. M., Pompei E., Dallapiccola B. Radiographic findings in Wiedemann-Rautenstrauch syndrome. Pediatr Radiol. 1992;22(6):474–475. doi: 10.1007/BF02013521. [DOI] [PubMed] [Google Scholar]
  6. Ohashi H., Eguchi T., Kajii T. Neonatal progeroid syndrome: report of a Japanese infant. Jinrui Idengaku Zasshi. 1987 Sep;32(3):253–256. doi: 10.1007/BF01876880. [DOI] [PubMed] [Google Scholar]
  7. Rautenstrauch T., Snigula F. Progeria: a cell culture study and clinical report of familial incidence. Eur J Pediatr. 1977 Jan 26;124(2):101–111. doi: 10.1007/BF00477545. [DOI] [PubMed] [Google Scholar]
  8. Rautenstrauch T., Snigula F., Wiedemann H. R. Neonatales progeroides Syndrom (Wiedemann-Rautenstrauch). Eine follow-up-Studie. Klin Padiatr. 1994 Nov-Dec;206(6):440–443. doi: 10.1055/s-2008-1046647. [DOI] [PubMed] [Google Scholar]
  9. Rudin C., Thommen L., Fliegel C., Steinmann B., Bühler U. The neonatal pseudo-hydrocephalic progeroid syndrome (Wiedemann-Rautenstrauch). Report of a new patient and review of the literature. Eur J Pediatr. 1988 May;147(4):433–438. doi: 10.1007/BF00496430. [DOI] [PubMed] [Google Scholar]
  10. Snigula F., Rautenstrauch T. A new neonatal progeroid syndrome. Eur J Pediatr. 1981 Jul;136(3):325–325. doi: 10.1007/BF00443003. [DOI] [PubMed] [Google Scholar]
  11. Wiedemann H. R. An unidentified neonatal progeroid syndrome: follow-up report. Eur J Pediatr. 1979 Jan 18;130(1):65–70. doi: 10.1007/BF00441901. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Medical Genetics are provided here courtesy of BMJ Publishing Group

RESOURCES