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. 1988 Sep;42(3):235–242. doi: 10.1136/jech.42.3.235

The Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC): past medical history in children with cancer.

A L Hartley 1, J M Birch 1, P A McKinney 1, V Blair 1, M D Teare 1, J Carrette 1, J R Mann 1, C A Stiller 1, G J Draper 1, H E Johnston 1, et al.
PMCID: PMC1052732  PMID: 3251004

Abstract

The Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC) collected interview and medical information relating to the child's past medical experiences from parents of 555 children diagnosed with cancer and parents of 1110 unaffected matched controls. No significant associations emerged overall for ante-natal care, place and mode of delivery, length of gestation, birth weight, condition at birth, special care, neonatal procedures or breast-feeding. Few risk factors relating to previous illnesses and medication were found, although increasing numbers of illnesses appeared to be associated with an increased risk of childhood cancer, particularly acute lymphoblastic leukaemia. A highly significant excess of case children had not been immunised (p = 0.005). In general, these results indicate that past medical experiences have little influence on the development of cancer in children.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arundel S. E., Kinnier-Wilson L. M. Parental occupations and cancer: a review of the literature. J Epidemiol Community Health. 1986 Mar;40(1):30–36. doi: 10.1136/jech.40.1.30. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bader J. L., Meadows A. T., Zimmerman L. E., Rorke L. B., Voute P. A., Champion L. A., Miller R. W. Bilateral retinoblastoma with ectopic intracranial retinoblastoma: trilateral retinoblastoma. Cancer Genet Cytogenet. 1982 Mar;5(3):203–213. doi: 10.1016/0165-4608(82)90026-7. [DOI] [PubMed] [Google Scholar]
  3. Bernard S. M., Cartwright R. A., Darwin C. M., Richards I. D., Roberts B., O'Brien C., Bird C. C. Hodgkin's disease: case control epidemiological study in Yorkshire. Br J Cancer. 1987 Jan;55(1):85–90. doi: 10.1038/bjc.1987.18. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Birch J. M., Mann J. R., Cartwright R. A., Draper G. J., Waterhouse J. A., Hartley A. L., Johnston H. E., McKinney P. A., Stiller C. A., Hopton P. A. The Inter-Regional Epidemiological Study of Childhood Cancer (IRESCO). Study design, control selection and data collection. Br J Cancer. 1985 Dec;52(6):915–922. doi: 10.1038/bjc.1985.277. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Bithell J. F., Stewart A. M. Pre-natal irradiation and childhood malignancy: a review of British data from the Oxford Survey. Br J Cancer. 1975 Mar;31(3):271–287. doi: 10.1038/bjc.1975.62. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Daling J. R., Starzyk P., Olshan A. F., Weiss N. S. Birth weight and the incidence of childhood cancer. J Natl Cancer Inst. 1984 May;72(5):1039–1041. [PubMed] [Google Scholar]
  7. Eisenberg D. E., Sorahan T. Birth weight and childhood cancer deaths. J Natl Cancer Inst. 1987 Jun;78(6):1095–1100. [PubMed] [Google Scholar]
  8. Fasal E., Jackson E. W., Klauber M. R. Birth characteristics and leukemia in childhood. J Natl Cancer Inst. 1971 Sep;47(3):501–509. [PubMed] [Google Scholar]
  9. Herbst A. L., Ulfelder H., Poskanzer D. C. Adenocarcinoma of the vagina. Association of maternal stilbestrol therapy with tumor appearance in young women. N Engl J Med. 1971 Apr 15;284(15):878–881. doi: 10.1056/NEJM197104222841604. [DOI] [PubMed] [Google Scholar]
  10. Hopton P. A., McKinney P. A., Cartwright R. A., Mann J. R., Birch J. M., Hartley A. L., Waterhouse J. A., Johnston H. E., Draper G. J., Stiller C. A. X-rays in pregnancy and the risk of childhood cancer. Lancet. 1985 Oct 5;2(8458):773–773. doi: 10.1016/s0140-6736(85)90644-0. [DOI] [PubMed] [Google Scholar]
  11. Kneale G. W., Stewart A. M., Wilson L. M. Immunizations against infectious diseases and childhood cancers. Cancer Immunol Immunother. 1986;21(2):129–132. doi: 10.1007/BF00199860. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. McKinney P. A., Cartwright R. A., Saiu J. M., Mann J. R., Stiller C. A., Draper G. J., Hartley A. L., Hopton P. A., Birch J. M., Waterhouse J. A. The inter-regional epidemiological study of childhood cancer (IRESCC): a case control study of aetiological factors in leukaemia and lymphoma. Arch Dis Child. 1987 Mar;62(3):279–287. doi: 10.1136/adc.62.3.279. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Otten J., Smets R., De Jager R., Gerard A., Maurus R. Hepatoblastoma in an infant after contraceptive intake during pregnancey. N Engl J Med. 1977 Jul 28;297(4):222–222. doi: 10.1056/nejm197707282970417. [DOI] [PubMed] [Google Scholar]
  14. Pendergrass T. W. Letter: Fetal hydantoin syndrome and neuroblastoma. Lancet. 1976 Jul 17;2(7977):150–150. doi: 10.1016/s0140-6736(76)92882-8. [DOI] [PubMed] [Google Scholar]
  15. Shu X. O., Gao Y. T., Linet M. S., Brinton L. A., Gao R. N., Jin F., Fraumeni J. F., Jr Chloramphenicol use and childhood leukaemia in Shanghai. Lancet. 1987 Oct 24;2(8565):934–937. doi: 10.1016/s0140-6736(87)91420-6. [DOI] [PubMed] [Google Scholar]
  16. Vianna N. J., Lawrence C. E., Davies J. N., Arbuckle J., Harris S., Marani W., Wilkinson J. Tonsillectomy and childhood Hodgkin's disease. Lancet. 1980 Aug 16;2(8190):338–340. doi: 10.1016/s0140-6736(80)90339-6. [DOI] [PubMed] [Google Scholar]
  17. Winkelmann R. K., Rajka G. Atopic dermatitis and Hodgkin's disease. Acta Derm Venereol. 1983;63(2):176–177. [PubMed] [Google Scholar]
  18. de-Thé G., Geser A., Day N. E., Tukei P. M., Williams E. H., Beri D. P., Smith P. G., Dean A. G., Bronkamm G. W., Feorino P. Epidemiological evidence for causal relationship between Epstein-Barr virus and Burkitt's lymphoma from Ugandan prospective study. Nature. 1978 Aug 24;274(5673):756–761. doi: 10.1038/274756a0. [DOI] [PubMed] [Google Scholar]
  19. van Steensel-Moll H. A., Valkenburg H. A., van Zanen G. E. Childhood leukemia and infectious diseases in the first year of life: a register-based case-control study. Am J Epidemiol. 1986 Oct;124(4):590–594. doi: 10.1093/oxfordjournals.aje.a114431. [DOI] [PubMed] [Google Scholar]

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