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. 1965 Mar;13(2):190–193. doi: 10.1128/am.13.2.190-193.1965

Effects of Minerals on Neomycin Production by Streptomyces fradiae

M K Majumdar 1, S K Majumdar 1
PMCID: PMC1058219  PMID: 14325877

Abstract

A study was made on the mineral requirements of Streptomyces fradiae strain 3535 for neomycin production. It was observed that optimal levels of the elements Ca, Fe, and Zn per milliliter of a synthetic medium for neomycin production were 10.8, 1.0, and 0.115 μg, respectively. K2HPO4 was required at a concentration of 0.1% for maximal yield of neomycin, whereas NaCl and the metals Mn and Cu were without any effect. High doses of Zn (0.23 μg/ml or above) caused destruction of neomycin after the fifth day of fermentation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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