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. 1993 Jan;50(1):79–84. doi: 10.1136/oem.50.1.79

non-Hodgkin's lymphoma and occupation in Sweden: a registry based analysis.

M S Linet 1, H S Malker 1, J K McLaughlin 1, J A Weiner 1, W J Blot 1, J L Ericsson 1, J F Fraumeni Jr 1
PMCID: PMC1061238  PMID: 8431395

Abstract

Incidence of non-Hodgkin's lymphoma in different employment categories was evaluated from the Swedish Cancer-Environment Registry, which links cancer incidence during 1961 to 1979 with occupational information from the 1960 census. New associations were found for men employed in shoemaking and shoe repair, porcelain and earthenware industries, education, and other white collar occupations. Several findings supported associations found in other countries, including excesses among woodworkers, furniture makers, electric power plant workers, farmers, dairy workers, lorry drivers, and other land transport workers. Risks were not increased among chemists, chemical or rubber manufacturing workers, or petrochemical refinery workers. Caution must be used in drawing causal inferences from these linked registry data because information on exposure and duration of employment is not available. Nevertheless, this study has suggested new clues to possible occupational determinants of non-Hodgkin's lymphoma.

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Selected References

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  1. Aksoy M. Different types of malignancies due to occupational exposure to benzene: a review of recent observations in Turkey. Environ Res. 1980 Oct;23(1):181–190. doi: 10.1016/0013-9351(80)90104-8. [DOI] [PubMed] [Google Scholar]
  2. Aksoy M. Malignancies due to occupational exposure to benzene. Am J Ind Med. 1985;7(5-6):395–402. doi: 10.1002/ajim.4700070506. [DOI] [PubMed] [Google Scholar]
  3. Balarajan R. Malignant lymphomas in road transport workers. J Epidemiol Community Health. 1983 Dec;37(4):279–280. doi: 10.1136/jech.37.4.279. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Blair A., Malker H., Cantor K. P., Burmeister L., Wiklund K. Cancer among farmers. A review. Scand J Work Environ Health. 1985 Dec;11(6):397–407. doi: 10.5271/sjweh.2208. [DOI] [PubMed] [Google Scholar]
  5. Boffetta P., Stellman S. D., Garfinkel L. Diesel exhaust exposure and mortality among males in the American Cancer Society prospective study. Am J Ind Med. 1988;14(4):403–415. doi: 10.1002/ajim.4700140405. [DOI] [PubMed] [Google Scholar]
  6. Brandt L. Leukaemia and lymphoma risks derived from solvents. Med Oncol Tumor Pharmacother. 1987;4(3-4):199–205. doi: 10.1007/BF02934516. [DOI] [PubMed] [Google Scholar]
  7. Brownson R. C., Reif J. S. A cancer registry-based study of occupational risk for lymphoma, multiple myeloma and leukaemia. Int J Epidemiol. 1988 Mar;17(1):27–32. doi: 10.1093/ije/17.1.27. [DOI] [PubMed] [Google Scholar]
  8. Burmeister L. F. Cancer mortality in Iowa farmers, 1971-78. J Natl Cancer Inst. 1981 Mar;66(3):461–464. [PubMed] [Google Scholar]
  9. Cantor K. P. Farming and mortality from non-Hodgkin's lymphoma: a case-control study. Int J Cancer. 1982 Mar 15;29(3):239–247. doi: 10.1002/ijc.2910290303. [DOI] [PubMed] [Google Scholar]
  10. Cantor K. P., Fraumeni J. F., Jr Distribution of non-Hodgkin's lymphoma in the United States between 1950 and 1975. Cancer Res. 1980 Aug;40(8 Pt 1):2645–2652. [PubMed] [Google Scholar]
  11. Cartwright R. A., McKinney P. A., O'Brien C., Richards I. D., Roberts B., Lauder I., Darwin C. M., Bernard S. M., Bird C. C. Non-Hodgkin's lymphoma: case control epidemiological study in Yorkshire. Leuk Res. 1988;12(1):81–88. doi: 10.1016/s0145-2126(98)80012-x. [DOI] [PubMed] [Google Scholar]
  12. Decouflé P., Walrath J. Proportionate mortality among US shoeworkers, 1966-1977. Am J Ind Med. 1983;4(4):523–532. doi: 10.1002/ajim.4700040406. [DOI] [PubMed] [Google Scholar]
  13. Dick F., VanLier S., Banks P., Frizzera G., Witrak G., Gibson R., Everett G., Schuman L., Isacson P., O'Conor G. Use of the working formulation for non-Hodgkin's lymphoma in epidemiologic studies: agreement between reported diagnoses and a panel of experienced pathologists. J Natl Cancer Inst. 1987 Jun;78(6):1137–1144. [PubMed] [Google Scholar]
  14. Dubrow R., Paulson J. O., Indian R. W. Farming and malignant lymphoma in Hancock County, Ohio. Br J Ind Med. 1988 Jan;45(1):25–28. doi: 10.1136/oem.45.1.25. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Dubrow R., Wegman D. H. Cancer and occupation in Massachusetts: a death certificate study. Am J Ind Med. 1984;6(3):207–230. doi: 10.1002/ajim.4700060305. [DOI] [PubMed] [Google Scholar]
  16. Fasal E., Jackson E. W., Klauber M. R. Leukemia and lymphoma mortality and farm residence. Am J Epidemiol. 1968 Mar;87(2):267–274. doi: 10.1093/oxfordjournals.aje.a120817. [DOI] [PubMed] [Google Scholar]
  17. Franceschi S., Serraino D., Bidoli E., Talamini R., Tirelli U., Carbone A., La Vecchia C. The epidemiology of non-Hodgkin's lymphoma in the north-east of Italy: a hospital-based case-control study. Leuk Res. 1989;13(6):465–472. doi: 10.1016/0145-2126(89)90168-9. [DOI] [PubMed] [Google Scholar]
  18. Franceschi S., Serraino D., Carbone A., Talamini R., La Vecchia C. Dietary factors and non-Hodgkin's lymphoma: a case-control study in the northeastern part of Italy. Nutr Cancer. 1989;12(4):333–341. doi: 10.1080/01635588909514034. [DOI] [PubMed] [Google Scholar]
  19. Francis D. P., Curran J. W., Essex M. Epidemic acquired immune deficiency syndrome: epidemiologic evidence for a transmissible agent. J Natl Cancer Inst. 1983 Jul;71(1):1–4. [PubMed] [Google Scholar]
  20. Garabrant D. H., Wegman D. H. Cancer mortality among shoe and leather workers in Massachusetts. Am J Ind Med. 1984;5(4):303–314. doi: 10.1002/ajim.4700050407. [DOI] [PubMed] [Google Scholar]
  21. Giles G. G., Lickiss J. N., Baikie M. J., Lowenthal R. M., Panton J. Myeloproliferative and lymphoproliferative disorders in Tasmania, 1972-80: occupational and familial aspects. J Natl Cancer Inst. 1984 Jun;72(6):1233–1240. [PubMed] [Google Scholar]
  22. Goldsmith J. R., Guidotti T. L. Environmental factors in the epidemiology of lymphosarcoma. Pathol Annu. 1977;12(Pt 2):411–425. [PubMed] [Google Scholar]
  23. Gubéran E., Usel M., Raymond L., Tissot R., Sweetnam P. M. Disability, mortality, and incidence of cancer among Geneva painters and electricians: a historical prospective study. Br J Ind Med. 1989 Jan;46(1):16–23. doi: 10.1136/oem.46.1.16. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Hardell L., Eriksson M., Lenner P., Lundgren E. Malignant lymphoma and exposure to chemicals, especially organic solvents, chlorophenols and phenoxy acids: a case-control study. Br J Cancer. 1981 Feb;43(2):169–176. doi: 10.1038/bjc.1981.25. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Howe G. R., Lindsay J. P. A follow-up study of a ten-percent sample of the Canadian labor force. I. Cancer mortality in males, 1965-73. J Natl Cancer Inst. 1983 Jan;70(1):37–44. [PubMed] [Google Scholar]
  26. La Vecchia C., Negri E., D'Avanzo B., Franceschi S. Occupation and lymphoid neoplasms. Br J Cancer. 1989 Sep;60(3):385–388. doi: 10.1038/bjc.1989.290. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Maizlish N., Beaumont J., Singleton J. Mortality among California highway workers. Am J Ind Med. 1988;13(3):363–379. doi: 10.1002/ajim.4700130306. [DOI] [PubMed] [Google Scholar]
  28. McDowall M. E. Mortality of persons resident in the vicinity of electricity transmission facilities. Br J Cancer. 1986 Feb;53(2):271–279. doi: 10.1038/bjc.1986.45. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. McLaughlin J. K., Malker H. S., Malker B. K., Stone B. J., Ericsson J. L., Blot W. J., Weiner J. A., Fraumeni J. F., Jr Registry-based analysis of occupational risks for primary liver cancer in Sweden. Cancer Res. 1987 Jan 1;47(1):287–291. [PubMed] [Google Scholar]
  30. Milham S., Jr, Demers R. Y. Mortality among pulp and paper workers. J Occup Med. 1984 Nov;26(11):844–846. doi: 10.1097/00043764-198411000-00016. [DOI] [PubMed] [Google Scholar]
  31. Milham S., Jr Mortality from leukemia in workers exposed to electrical and magnetic fields. N Engl J Med. 1982 Jul 22;307(4):249–249. doi: 10.1056/nejm198207223070412. [DOI] [PubMed] [Google Scholar]
  32. Miller J. M., Miller L. D., Olson C., Gillette K. G. Virus-like particles in phytohemagglutinin-stimulated lymphocyte cultures with reference to bovine lymphosarcoma. J Natl Cancer Inst. 1969 Dec;43(6):1297–1305. [PubMed] [Google Scholar]
  33. Olin G. R., Ahlbom A. The cancer mortality among Swedish chemists graduated during three decades. A comparison with the general population and with a cohort of architects. Environ Res. 1980 Jun;22(1):154–161. doi: 10.1016/0013-9351(80)90127-9. [DOI] [PubMed] [Google Scholar]
  34. Olin R., Vågerö D., Ahlbom A. Mortality experience of electrical engineers. Br J Ind Med. 1985 Mar;42(3):211–212. doi: 10.1136/oem.42.3.211. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Olsson H., Brandt L. Risk of non-Hodgkin's lymphoma among men occupationally exposed to organic solvents. Scand J Work Environ Health. 1988 Aug;14(4):246–251. doi: 10.5271/sjweh.1925. [DOI] [PubMed] [Google Scholar]
  36. Ott M. G., Teta M. J., Greenberg H. L. Lymphatic and hematopoietic tissue cancer in a chemical manufacturing environment. Am J Ind Med. 1989;16(6):631–643. doi: 10.1002/ajim.4700160603. [DOI] [PubMed] [Google Scholar]
  37. Pearce N. E., Sheppard R. A., Smith A. H., Teague C. A. Non-Hodgkin's lymphoma and farming: an expanded case-control study. Int J Cancer. 1987 Feb 15;39(2):155–161. doi: 10.1002/ijc.2910390206. [DOI] [PubMed] [Google Scholar]
  38. Pearce N., Smith A. H., Reif J. S. Increased risks of soft tissue sarcoma, malignant lymphoma, and acute myeloid leukemia in abattoir workers. Am J Ind Med. 1988;14(1):63–72. doi: 10.1002/ajim.4700140108. [DOI] [PubMed] [Google Scholar]
  39. Persson B., Dahlander A. M., Fredriksson M., Brage H. N., Ohlson C. G., Axelson O. Malignant lymphomas and occupational exposures. Br J Ind Med. 1989 Aug;46(8):516–520. doi: 10.1136/oem.46.8.516. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Pippard E. C., Acheson E. D. The mortality of boot and shoe makers, with special reference to cancer. Scand J Work Environ Health. 1985 Aug;11(4):249–255. doi: 10.5271/sjweh.2223. [DOI] [PubMed] [Google Scholar]
  41. Savitz D. A., Pearce N. E., Poole C. Methodological issues in the epidemiology of electromagnetic fields and cancer. Epidemiol Rev. 1989;11:59–78. doi: 10.1093/oxfordjournals.epirev.a036045. [DOI] [PubMed] [Google Scholar]
  42. Schumacher M. C., Delzell E. A death-certificate case-control study of non-Hodgkin's lymphoma and occupation in men in North Carolina. Am J Ind Med. 1988;13(3):317–330. doi: 10.1002/ajim.4700130303. [DOI] [PubMed] [Google Scholar]
  43. Stewart S. E., Mitchell E. Z., Whang J. J., Dunlop W. R., Ben T., Nomura S. Viruses in human tumors. I. Hodgkin's disease. J Natl Cancer Inst. 1969 Jul;43(1):1–14. [PubMed] [Google Scholar]
  44. Svirchev L. M., Gallagher R. P., Band P. R., Threlfall W. J., Spinelli J. J. Gastric cancer and lymphosarcoma among wood and pulp workers. J Occup Med. 1986 Apr;28(4):264–265. [PubMed] [Google Scholar]
  45. Törnqvist S., Norell S., Ahlbom A., Knave B. Cancer in the electric power industry. Br J Ind Med. 1986 Mar;43(3):212–213. doi: 10.1136/oem.43.3.212. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. VIGLIANI E. C., SAITA G. BENZENE AND LEUKEMIA. N Engl J Med. 1964 Oct 22;271:872–876. doi: 10.1056/NEJM196410222711703. [DOI] [PubMed] [Google Scholar]
  47. Vågerö D., Ahlbom A., Olin R., Sahlsten S. Cancer morbidity among workers in the telecommunications industry. Br J Ind Med. 1985 Mar;42(3):191–195. doi: 10.1136/oem.42.3.191. [DOI] [PMC free article] [PubMed] [Google Scholar]
  48. Vågerö D., Persson G. Occurrence of cancer in socioeconomic groups in Sweden. An analysis based on the Swedish Cancer Environment Registry. Scand J Soc Med. 1986;14(3):151–160. doi: 10.1177/140349488601400308. [DOI] [PubMed] [Google Scholar]
  49. Wallace L. A. Major sources of benzene exposure. Environ Health Perspect. 1989 Jul;82:165–169. doi: 10.1289/ehp.8982165. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. Walrath J., Decouflé P., Thomas T. L. Mortality among workers in a shoe manufacturing company. Am J Ind Med. 1987;12(5):615–623. doi: 10.1002/ajim.4700120514. [DOI] [PubMed] [Google Scholar]
  51. Weisenburger D. D. Environmental epidemiology of non-Hodgkin's lymphoma in eastern Nebraska. Am J Ind Med. 1990;18(3):303–305. doi: 10.1002/ajim.4700180310. [DOI] [PubMed] [Google Scholar]
  52. Wertheimer N., Leeper E. Adult cancer related to electrical wires near the home. Int J Epidemiol. 1982 Dec;11(4):345–355. doi: 10.1093/ije/11.4.345. [DOI] [PubMed] [Google Scholar]
  53. Wiklund K., Dich J., Holm L. E. Risk of malignant lymphoma in Swedish pesticide appliers. Br J Cancer. 1987 Oct;56(4):505–508. doi: 10.1038/bjc.1987.234. [DOI] [PMC free article] [PubMed] [Google Scholar]
  54. Wiklund K., Holm L. E. Soft tissue sarcoma risk in Swedish agricultural and forestry workers. J Natl Cancer Inst. 1986 Feb;76(2):229–234. [PubMed] [Google Scholar]
  55. Wiklund K., Lindefors B. M., Holm L. E. Risk of malignant lymphoma in Swedish agricultural and forestry workers. Br J Ind Med. 1988 Jan;45(1):19–24. doi: 10.1136/oem.45.1.19. [DOI] [PMC free article] [PubMed] [Google Scholar]
  56. Wills J. H. Nasal carcinoma in woodworkers: a review. J Occup Med. 1982 Jul;24(7):526–530. [PubMed] [Google Scholar]
  57. Wong O. An industry wide mortality study of chemical workers occupationally exposed to benzene. II. Dose response analyses. Br J Ind Med. 1987 Jun;44(6):382–395. doi: 10.1136/oem.44.6.382. [DOI] [PMC free article] [PubMed] [Google Scholar]
  58. Wong O., Raabe G. K. Critical review of cancer epidemiology in petroleum industry employees, with a quantitative meta-analysis by cancer site. Am J Ind Med. 1989;15(3):283–310. doi: 10.1002/ajim.4700150305. [DOI] [PubMed] [Google Scholar]
  59. Woods J. S., Polissar L., Severson R. K., Heuser L. S., Kulander B. G. Soft tissue sarcoma and non-Hodgkin's lymphoma in relation to phenoxyherbicide and chlorinated phenol exposure in western Washington. J Natl Cancer Inst. 1987 May;78(5):899–910. [PubMed] [Google Scholar]

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