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. 1989 Jun;90(2):367–371. doi: 10.1104/pp.90.2.367

Malic Enzymes of Higher Plants

Characteristics, Regulation, and Physiological Function

Randolph T Wedding 1
PMCID: PMC1061728  PMID: 16666776

Abstract

The characteristics and distribution of the malic enzyme in plants is discussed as well as those features which appear to be limited to the plant NAD malic enzyme. Regulation of the malic enzyme as it relates to the physiological roles of this enzyme is also discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Canellas P. F., Wedding R. T. Kinetic properties of NAD malic enzyme from cauliflower. Arch Biochem Biophys. 1984 Mar;229(2):414–425. doi: 10.1016/0003-9861(84)90171-1. [DOI] [PubMed] [Google Scholar]
  2. Canellas P. F., Wedding R. T. Substrate and metal ion interactions in the NAD+ malic enzyme from cauliflower. Arch Biochem Biophys. 1980 Jan;199(1):259–264. doi: 10.1016/0003-9861(80)90279-9. [DOI] [PubMed] [Google Scholar]
  3. Day D. A., Neuburger M., Douce R. Activation of NAD-linked malic enzyme in intact plant mitochondria by exogenous coenzyme A. Arch Biochem Biophys. 1984 May 15;231(1):233–242. doi: 10.1016/0003-9861(84)90383-7. [DOI] [PubMed] [Google Scholar]
  4. Dittrich P. Nicotinamide Adenine Dinucleotide-specific "Malic" Enzyme in Kalanchoë daigremontiana and Other Plants Exhibiting Crassulacean Acid Metabolism. Plant Physiol. 1976 Feb;57(2):310–314. doi: 10.1104/pp.57.2.310. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Grissom C. B., Canellas P. F., Wedding R. T. Allosteric regulation of the NAD malic enzyme from cauliflower: activation by fumarate and coenzyme A. Arch Biochem Biophys. 1983 Jan;220(1):133–144. doi: 10.1016/0003-9861(83)90394-6. [DOI] [PubMed] [Google Scholar]
  6. Grissom C. B., Willeford K. O., Wedding R. T. Isotope effect studies of the chemical mechanism of nicotinamide adenine dinucleotide malic enzyme from Crassula. Biochemistry. 1987 May 5;26(9):2594–2596. doi: 10.1021/bi00383a027. [DOI] [PubMed] [Google Scholar]
  7. Grover S. D., Canellas P. F., Wedding R. T. Purification of NAD malic enzyme from potato and investigation of some physical and kinetic properties. Arch Biochem Biophys. 1981 Jul;209(2):396–407. doi: 10.1016/0003-9861(81)90297-6. [DOI] [PubMed] [Google Scholar]
  8. Grover S. D., Wedding R. T. Kinetic Ramifications of the Association-Dissociation Behavior of NAD Malic Enzyme : A Possible Regulatory Mechanism. Plant Physiol. 1982 Oct;70(4):1169–1172. doi: 10.1104/pp.70.4.1169. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Grover S. D., Wedding R. T. Modulation of the activity of NAD malic enzyme from solanum tuberosum by changes in oligomeric state. Arch Biochem Biophys. 1984 Nov 1;234(2):418–425. doi: 10.1016/0003-9861(84)90288-1. [DOI] [PubMed] [Google Scholar]
  10. Hatch M. D., Mau S. L., Kagawa T. Properties of leaf NAD malic enzyme from plants with C4 pathway photosynthesis. Arch Biochem Biophys. 1974 Nov;165(1):188–200. doi: 10.1016/0003-9861(74)90155-6. [DOI] [PubMed] [Google Scholar]
  11. Macrae A. R. Isolation and properties of a 'malic' enzyme from cauliflower bud mitochondria. Biochem J. 1971 May;122(4):495–501. doi: 10.1042/bj1220495. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Outlaw W. H., Manchester J., Brown P. H. High Levels of Malic Enzyme Activities in Vicia faba L. Epidermal Tissue. Plant Physiol. 1981 Nov;68(5):1047–1051. doi: 10.1104/pp.68.5.1047. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Park S. H., Harris B. G., Cook P. F. pH dependence of kinetic parameters for oxalacetate decarboxylation and pyruvate reduction reactions catalyzed by malic enzyme. Biochemistry. 1986 Jul 1;25(13):3752–3759. doi: 10.1021/bi00361a004. [DOI] [PubMed] [Google Scholar]
  14. Wedding R. T., Black M. K. Physical and Kinetic Properties and Regulation of the NAD Malic Enzyme Purified from Leaves of Crassula argentea. Plant Physiol. 1983 Aug;72(4):1021–1028. doi: 10.1104/pp.72.4.1021. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Willeford K. O., Wedding R. T. Evidence for a multiple subunit composition of plant NAD malic enzyme. J Biol Chem. 1987 Jun 15;262(17):8423–8429. [PubMed] [Google Scholar]
  16. Willeford K. O., Wedding R. T. Regulation of the NAD Malic Enzyme from Crassula. Plant Physiol. 1986 Mar;80(3):792–795. doi: 10.1104/pp.80.3.792. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Willeford K. O., Wedding R. T. pH Effects on the Activity and Regulation of the NAD Malic Enzyme. Plant Physiol. 1987 Aug;84(4):1084–1087. doi: 10.1104/pp.84.4.1084. [DOI] [PMC free article] [PubMed] [Google Scholar]

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