Skip to main content
PMC home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1957 Apr;36(4):515–529. doi: 10.1172/JCI103449

The Renal Response in Man to Acute Experimental Respiratory Alkalosis and Acidosis1

E S Barker 1,2,3,4,2,3, R B Singer 1,2,3,4,4, J R Elkinton 1,2,3,4,2, J K Clark 1,2,3,4
PMCID: PMC1072673  PMID: 13416380

Full text

PDF
520

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BARBOUR A., BULL G. M., EVANS B. M., JONES N. C. H., LOGOTHETOPOULOS J. The effect of breathing 5 to 7% carbon dioxide on urine flow and mineral excretion. Clin Sci. 1953 Feb;12(1):1–13. [PubMed] [Google Scholar]
  2. BERLINER R. W., KENNEDY T. J., Jr, ORLOFF J. Relationship between acidification of the urine and potassium metabolism; effect of carbonic anhydrase inhibition on potassium excretion. Am J Med. 1951 Sep;11(3):274–282. doi: 10.1016/0002-9343(51)90165-9. [DOI] [PubMed] [Google Scholar]
  3. BRAZEAU P., GILMAN A. Effect of plasma CO2 tension on renal tubular reabsorption of bicarbonate. Am J Physiol. 1953 Oct;175(1):33–38. doi: 10.1152/ajplegacy.1953.175.1.33. [DOI] [PubMed] [Google Scholar]
  4. Brod J., Sirota J. H. THE RENAL CLEARANCE OF ENDOGENOUS "CREATININE" IN MAN. J Clin Invest. 1948 Sep;27(5):645–654. doi: 10.1172/JCI102012. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. COOKE R. E., SEGAR W. E., CHEEK D. B., COVILLE F. E., DARROW D. C. The extrarenal correction of alkalosis associated with potassium deficiency. J Clin Invest. 1952 Aug;31(8):798–805. doi: 10.1172/JCI102665. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. DENTON D. A., MAXWELL M., MCDONALD I. R., MUNRO J., WILLIAMS W. Renal regulation of the extracellular fluid in acute respiratory acidaemia. Aust J Exp Biol Med Sci. 1952 Dec;30(6):489–510. doi: 10.1038/icb.1952.48. [DOI] [PubMed] [Google Scholar]
  7. DORMAN P. J., SULLIVAN W. J., PITTS R. F. The renal response to acute respiratory acidosis. J Clin Invest. 1954 Jan;33(1):82–90. doi: 10.1172/JCI102874. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. DOWDS E. G., BRICKNER E. W., SELKURT E. E. Renal response to hypercapnia. Proc Soc Exp Biol Med. 1953 Oct;84(1):15–20. doi: 10.3181/00379727-84-20527. [DOI] [PubMed] [Google Scholar]
  9. Darrow D. C. CHANGES IN MUSCLE COMPOSITION IN ALKALOSIS. J Clin Invest. 1946 May;25(3):324–330. doi: 10.1172/JCI101712. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. ELKINTON J. R., SINGER R. B., BARKER E. S., CLARK J. K. Effects in man of acute experimental respiratory alkalosis and acidosis on ionic transfers in the total body fluids. J Clin Invest. 1955 Nov;34(11):1671–1690. doi: 10.1172/JCI103221. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. FULLER G. R., MACLEOD M. B. Excretion of titratable acid during acute respiratory disturbances of acid-base balance. Am J Physiol. 1956 Sep;186(3):505–510. doi: 10.1152/ajplegacy.1956.186.3.505. [DOI] [PubMed] [Google Scholar]
  12. HILTON J. G., CAPECI N. E., KISS G. T., KRUESI O. R., GLAVIANO V. V., WEGRIA R. The effect of acute elevation of the plasma chloride concentration on the renal excretion of bicarbonate during acute respiratory acidosis. J Clin Invest. 1956 May;35(5):481–487. doi: 10.1172/JCI103300. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. LONGSON D., MILLS J. N. The failure of the kidney to respond to respiratory acidosis. J Physiol. 1953 Oct;122(1):81–92. doi: 10.1113/jphysiol.1953.sp004980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. McDONALD I. R., COATS D. A., MUNRO J. The renal regulation of the extracellular ionic pattern during hyperventilation. Aust J Exp Biol Med Sci. 1953 Oct;31(5):425–439. doi: 10.1038/icb.1953.46. [DOI] [PubMed] [Google Scholar]
  15. OCHWADT B. Uber Rückresorption und Ausscheidung von Bicarbonat durch die Niere während der Hyperventilationsalkalose. Pflugers Arch. 1950;252(6):529–536. doi: 10.1007/BF00463529. [DOI] [PubMed] [Google Scholar]
  16. RELMAN A. S., ETSTEN B., SCHWARTZ W. B. The regulation of renal bicarbonate reabsorption by plasma carbon dioxide tension. J Clin Invest. 1953 Oct;32(10):972–978. doi: 10.1172/JCI102823. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. ROBERTS K. E., RANDALL H. T., SANDERS H. L., HOOD M. Effects of potassium on renal tubular reabsorption of bicarbonate. J Clin Invest. 1955 May;34(5):666–672. doi: 10.1172/JCI103116. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. SINGER R. B., CLARK J. K., BARKER E. S., CROSLEY A. P., Jr, ELKINTON J. R. The acute effects in man of rapid intravenous infusion of hypertonic sodium bicarbonate solution. I. Changes in acid-base balance and distribution of the excess buffer base. Medicine (Baltimore) 1955 Feb;34(1):51–95. doi: 10.1097/00005792-195502000-00003. [DOI] [PubMed] [Google Scholar]
  19. STANBURY S. W., THOMSON A. E. Diurnal variation in electrolyte excretion. Clin Sci. 1951 Aug;10(3):267–293. [PubMed] [Google Scholar]
  20. STANBURY S. W., THOMSON A. E. The renal response to respiratory alkalosis. Clin Sci. 1952 Nov;11(4):357–374. [PubMed] [Google Scholar]
  21. SULLIVAN W. J., DORMAN P. J. The renal response to chronic respiratory acidosis. J Clin Invest. 1955 Feb;34(2):268–276. doi: 10.1172/JCI103080. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Sartorius O. W., Roemmelt J. C., Pitts R. F., Calhoon D., Miner P. THE RENAL REGULATION OF ACID-BASE BALANCE IN MAN. IV. THE NATURE OF THE RENAL COMPENSATIONS IN AMMONIUM CHLORIDE ACIDOSIS. J Clin Invest. 1949 May;28(3):423–439. doi: 10.1172/JCI102087. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Schiess W. A., Ayer J. L., Lotspeich W. D., Pitts R. F., Miner P. THE RENAL REGULATION OF ACID-BASE BALANCE IN MAN. II. FACTORS AFFECTING THE EXCRETION OF TITRATABLE ACID BY THE NORMAL HUMAN SUBJECT. J Clin Invest. 1948 Jan;27(1):57–64. doi: 10.1172/JCI101924. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Smith H. W., Finkelstein N., Aliminosa L., Crawford B., Graber M. THE RENAL CLEARANCES OF SUBSTITUTED HIPPURIC ACID DERIVATIVES AND OTHER AROMATIC ACIDS IN DOG AND MAN. J Clin Invest. 1945 May;24(3):388–404. doi: 10.1172/JCI101618. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. WALLACE W. M., HOLLIDAY M., CUSHMAN M., ELKINTON J. R. The application of the internal standard flame photometer to the analysis of biologic material. J Lab Clin Med. 1951 Apr;37(4):621–629. [PubMed] [Google Scholar]
  26. YEOMANS A., STUECK G. H., Jr Clinical-chemical studies of acid-base abnormalities; changes in acid-base balance observed in renal and respiratory disease. Am J Med. 1952 Aug;13(2):183–208. doi: 10.1016/0002-9343(52)90156-3. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES