Skip to main content
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1957 Oct;36(10):1486–1497. doi: 10.1172/JCI103545

The Thyroid Hormone-Plasma Protein Complex in Man. I. Differences in Different States of Thyroid Function1,2

Milton W Hamolsky 1,2, Haskell E Ellison 1,2, A Stone Freedberg 1,2,3
PMCID: PMC1072748  PMID: 13475486

Full text

PDF
1488

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALBRIGHT E. C., LARSON F. C., DEISS W. P. Thyroxine binding capacity of serum alpha globulin in hypothyroid, euthyroid, and hyperthyroid subjects. J Clin Invest. 1955 Jan;34(1):44–47. doi: 10.1172/JCI103061. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. CRISPELL K. R., KAHANA S., HYER H. The effect of plasma on the in vitro uptake or binding by human red cells of radioactive I-131 labeled L-thyroxine and L-triiodothyronine. J Clin Invest. 1956 Jan;35(1):121–124. doi: 10.1172/JCI103246. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. DEISS W. P., ALBRIGHT E. C., LARSON F. C. A study of the nature of the circulating thyroid hormone in euthyroid and hyperthyroid subjects by use of paper electrophoresis. J Clin Invest. 1952 Nov;31(11):1000–1005. doi: 10.1172/JCI102683. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. DINGLEDINE W. S., PITTRIVERS R., STANBURY J. B. Nature and transport of the iodinated substances of the blood of normal subjects and of patients with thyroid disease. J Clin Endocrinol Metab. 1955 Jun;15(6):724–731. doi: 10.1210/jcem-15-6-724. [DOI] [PubMed] [Google Scholar]
  5. DOWLING J. T., FREINKEL N., INGBAR S. H. The influence of extracellular thyroxine-binding protein upon the accumulation of thyroxine by tissue slices. J Clin Invest. 1957 Jan;36(1 Pt 1):25–37. doi: 10.1172/JCI103406. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. FREEDBERG A. S., HAMOLSKY M. W., STEIN M. The thyroid hormone-plasma protein complex in man. II. A new in vitro method for study of uptake of labelled hormonal components by human erythrocytes. J Clin Endocrinol Metab. 1957 Jan;17(1):33–43. doi: 10.1210/jcem-17-1-33. [DOI] [PubMed] [Google Scholar]
  7. FREEDBERG A. S., KURLAND G. S., CHAMOVITZ D. L., URELES A. L. A critical analysis of the quantitative I131 therapy of thyrotoxicosis. J Clin Endocrinol Metab. 1952 Jan;12(1):86–111. doi: 10.1210/jcem-12-1-86. [DOI] [PubMed] [Google Scholar]
  8. FREINKEL N., DOWLING J. T., INGBAR S. H. The interaction of thyroxine with plasma proteins: localization of thyroxine-binding protein in Cohn fractions of plasma. J Clin Invest. 1955 Nov;34(11):1698–1709. doi: 10.1172/JCI103223. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. GROSS J., LEBLOND C. P. Metabolism of the thyroid hormone in the rat as shown by physiological doses of labeled thyroxine. J Biol Chem. 1950 Jun;184(2):489–500. [PubMed] [Google Scholar]
  10. GROSS J., PITT-RIVERS R. 3:5:3' -triiodothyronine. 1. Isolation from thyroid gland and synthesis. Biochem J. 1953 Mar;53(4):645–650. doi: 10.1042/bj0530645. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. GROSS J., PITT-RIVERS R. 3:5:3'-triiodothyronine. 2. Physiological activity. Biochem J. 1953 Mar;53(4):652–657. doi: 10.1042/bj0530652. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. GROSS J., PITT-RIVERS R. The identification of 3:5:3'-L-triiodothyronine in human plasma. Lancet. 1952 Mar 1;1(6705):439–441. doi: 10.1016/s0140-6736(52)91952-1. [DOI] [PubMed] [Google Scholar]
  13. HAMOLSKY M. W., FREEDBERG A. S., KURLAND G. S., WOLSKY L. The exchangeable thyroid hormonal pool. I. Its magnitude and rate of turnover in various thyroid states in man. J Clin Invest. 1953 May;32(5):453–457. doi: 10.1172/JCI102759. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. MAURER W., MULLER E. R. Zur Frage der Transportfunktion einzelner Serum-Eiweiss-Fraktionen für die organischen Jodverbindungen des Serums; papierelektrophoretische Untersuchung von J131-markierten Seren bei niedriger und hoher Strahlenbelastung der Schilddrüse. Biochem Z. 1953;324(5):325–336. [PubMed] [Google Scholar]
  15. RAWSON R. V., RALL J. E., PEARSON O. H., ROBBINS J., POPPELL H. F., WEST C. D. 1-Triiodothyronine versus 1-throxine; a comparison of their metabolic effects in human myxedema. Am J Med Sci. 1953 Oct;226(4):405–411. [PubMed] [Google Scholar]
  16. RAWSON R. V., RALL J. E., PEARSON O. H., ROBBINS J., POPPELL H. F., WEST C. D. 1-Triiodothyronine versus 1-throxine; a comparison of their metabolic effects in human myxedema. Am J Med Sci. 1953 Oct;226(4):405–411. [PubMed] [Google Scholar]
  17. ROBBINS J., RALL J. E., BECKER D. V., RAWSON R. W. The nature of the serum iodine after large doses of I131. J Clin Endocrinol Metab. 1952 Jul;12(7):856–874. doi: 10.1210/jcem-12-7-856. [DOI] [PubMed] [Google Scholar]
  18. ROBBINS J., RALL J. E. Thyroxine-binding capacity of serum in normal man. J Clin Invest. 1955 Aug;34(8):1324–1330. doi: 10.1172/JCI103179. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. ROBBINS J., RALL J. E. Zone electrophoresis in filter paper of serum I 131 after radioiodide administration. Proc Soc Exp Biol Med. 1952 Nov;81(2):530–536. doi: 10.3181/00379727-81-19930. [DOI] [PubMed] [Google Scholar]
  20. ROBBINS J. Reverse-flow zone electrophoresis; a method for determining the thyroxine-binding capacity of serum protein. Arch Biochem Biophys. 1956 Aug;63(2):461–469. doi: 10.1016/0003-9861(56)90062-5. [DOI] [PubMed] [Google Scholar]
  21. ROSENBERG I. N. The nature of the circulating thyroid hormone in Graves' disease. J Clin Invest. 1951 Jan;30(1):1–10. doi: 10.1172/JCI102409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. STERLING K., LASHOF J. C., MAN E. B. Disappearance from serum of I131-labeled l-thyroxine and l-triiodothyronine in euthyroid subjects. J Clin Invest. 1954 Jul;33(7):1031–1035. doi: 10.1172/JCI102970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. STERLING K., LASHOF J. C., MAN E. B. Disappearance from serum of I131-labeled l-thyroxine and l-triiodothyronine in euthyroid subjects. J Clin Invest. 1954 Jul;33(7):1031–1035. doi: 10.1172/JCI102970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. TONG W., TAUROG A., CHAIKOFF I. L. Nature of plasma iodine following destruction of the rat thyroid with I131. J Biol Chem. 1952 Mar;195(1):407–413. [PubMed] [Google Scholar]
  25. TUBIANA M. Mesure du temps de renouvellement d'hormone thyroïdienne naturelle marquée par le radioiode chez le lapin et chez l'homme. C R Seances Soc Biol Fil. 1951 Jul;145(13-14):1011–1013. [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES