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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1997 Jun;62(6):553–561. doi: 10.1136/jnnp.62.6.553

Genetic epidemiology of multiple sclerosis.

A Compston 1
PMCID: PMC1074136  PMID: 9219738

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Selected References

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  1. ALTER M., HALPERN L., KURLAND L. T., BORNSTEIN B., LEIBOWITZ U., SILBERSTEIN J. Multiple sclerosis in Israel. Prevalence among immigrants and native inhabitants. Arch Neurol. 1962 Oct;7:253–263. doi: 10.1001/archneur.1962.04210040005001. [DOI] [PubMed] [Google Scholar]
  2. Alter M., Kahana E., Loewenson R. Migration and risk of multiple sclerosis. Neurology. 1978 Nov;28(11):1089–1093. doi: 10.1212/wnl.28.11.1089. [DOI] [PubMed] [Google Scholar]
  3. Andersen O., Lygner P. E., Bergström T., Andersson M., Vahlne A. Viral infections trigger multiple sclerosis relapses: a prospective seroepidemiological study. J Neurol. 1993 Jul;240(7):417–422. doi: 10.1007/BF00867354. [DOI] [PubMed] [Google Scholar]
  4. Baskett P. J., Armstrong R. Anaesthetic problems in multiple sclerosis. Are certain agents contraindicated? Anaesthesia. 1970 Jul;25(3):397–401. doi: 10.1111/j.1365-2044.1970.tb00229.x. [DOI] [PubMed] [Google Scholar]
  5. Bauer H. J. Multiple sclerosis in Europe. J Neurol. 1987 May;234(4):195–206. doi: 10.1007/BF00618250. [DOI] [PubMed] [Google Scholar]
  6. Birk K., Ford C., Smeltzer S., Ryan D., Miller R., Rudick R. A. The clinical course of multiple sclerosis during pregnancy and the puerperium. Arch Neurol. 1990 Jul;47(7):738–742. doi: 10.1001/archneur.1990.00530070026007. [DOI] [PubMed] [Google Scholar]
  7. Carton H., Vlietinck R., Debruyne J., De Keyser J., D'Hooghe M. B., Loos R., Medaer R., Truyen L., Yee I. M., Sadovnick A. D. Risks of multiple sclerosis in relatives of patients in Flanders, Belgium. J Neurol Neurosurg Psychiatry. 1997 Apr;62(4):329–333. doi: 10.1136/jnnp.62.4.329. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Chakraborty R., Kamboh M. I., Nwankwo M., Ferrell R. E. Caucasian genes in American blacks: new data. Am J Hum Genet. 1992 Jan;50(1):145–155. [PMC free article] [PubMed] [Google Scholar]
  9. Cook S. D., Cromarty J. I., Tapp W., Poskanzer D., Walker J. D., Dowling P. C. Declining incidence of multiple sclerosis in the Orkney Islands. Neurology. 1985 Apr;35(4):545–551. doi: 10.1212/wnl.35.4.545. [DOI] [PubMed] [Google Scholar]
  10. Cook S. D., Gudmundsson G., Benedikz J., Dowling P. C. Multiple sclerosis and distemper in Iceland 1966-1978. Acta Neurol Scand. 1980 Apr;61(4):244–251. doi: 10.1111/j.1600-0404.1980.tb01489.x. [DOI] [PubMed] [Google Scholar]
  11. Dean G. Annual incidence, prevalence, and mortality of multiple sclerosis in white South-African-born and in white immigrants to South Africa. Br Med J. 1967 Jun 17;2(5554):724–730. doi: 10.1136/bmj.2.5554.724. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Delasnerie-Lauprêtre N., Alpérovitch A. Migration and age at onset of multiple sclerosis: some pitfalls of migrant studies. Acta Neurol Scand. 1992 Jun;85(6):408–411. doi: 10.1111/j.1600-0404.1992.tb06038.x. [DOI] [PubMed] [Google Scholar]
  13. Detels R., Brody J. A., Edgar A. H. Multiple sclerosis among American, Japanese and Chinese migrants to California and Washington. J Chronic Dis. 1972 Jan;25(1):3–10. doi: 10.1016/0021-9681(72)90016-1. [DOI] [PubMed] [Google Scholar]
  14. Duquette P., Murray T. J., Pleines J., Ebers G. C., Sadovnick D., Weldon P., Warren S., Paty D. W., Upton A., Hader W. Multiple sclerosis in childhood: clinical profile in 125 patients. J Pediatr. 1987 Sep;111(3):359–363. doi: 10.1016/s0022-3476(87)80454-7. [DOI] [PubMed] [Google Scholar]
  15. Ebers G. C., Bulman D. E., Sadovnick A. D., Paty D. W., Warren S., Hader W., Murray T. J., Seland T. P., Duquette P., Grey T. A population-based study of multiple sclerosis in twins. N Engl J Med. 1986 Dec 25;315(26):1638–1642. doi: 10.1056/NEJM198612253152603. [DOI] [PubMed] [Google Scholar]
  16. Ebers G. C., Kukay K., Bulman D. E., Sadovnick A. D., Rice G., Anderson C., Armstrong H., Cousin K., Bell R. B., Hader W. A full genome search in multiple sclerosis. Nat Genet. 1996 Aug;13(4):472–476. doi: 10.1038/ng0896-472. [DOI] [PubMed] [Google Scholar]
  17. Ebers G. C., Sadovnick A. D., Risch N. J. A genetic basis for familial aggregation in multiple sclerosis. Canadian Collaborative Study Group. Nature. 1995 Sep 14;377(6545):150–151. doi: 10.1038/377150a0. [DOI] [PubMed] [Google Scholar]
  18. Elian M., Dean G. Multiple sclerosis among the United Kingdom-born children of immigrants from the West Indies. J Neurol Neurosurg Psychiatry. 1987 Mar;50(3):327–332. doi: 10.1136/jnnp.50.3.327. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Elian M., Nightingale S., Dean G. Multiple sclerosis among United Kingdom-born children of immigrants from the Indian subcontinent, Africa and the West Indies. J Neurol Neurosurg Psychiatry. 1990 Oct;53(10):906–911. doi: 10.1136/jnnp.53.10.906. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Fog M., Hyllested K. Prevalence of disseminated sclerosis in the Faroes, the Orkneys and Shetland. Acta Neurol Scand. 1966;42(Suppl):9–11. doi: 10.1111/j.1600-0404.1966.tb01996.x. [DOI] [PubMed] [Google Scholar]
  21. Frith J. A., McLeod J. G. Pregnancy and multiple sclerosis. J Neurol Neurosurg Psychiatry. 1988 Apr;51(4):495–498. doi: 10.1136/jnnp.51.4.495. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Hammond S. R., McLeod J. G., Millingen K. S., Stewart-Wynne E. G., English D., Holland J. T., McCall M. G. The epidemiology of multiple sclerosis in three Australian cities: Perth, Newcastle and Hobart. Brain. 1988 Feb;111(Pt 1):1–25. doi: 10.1093/brain/111.1.1. [DOI] [PubMed] [Google Scholar]
  23. Kahana E., Zilber N., Abramson J. H., Biton V., Leibowitz Y., Abramsky O. Multiple sclerosis: genetic versus environmental aetiology: epidemiology in Israel updated. J Neurol. 1994 Mar;241(5):341–346. doi: 10.1007/BF00868444. [DOI] [PubMed] [Google Scholar]
  24. Kurtzke J. F. A reassessment of the distribution of multiple sclerosis. Part one. Acta Neurol Scand. 1975 Feb;51(2):110–136. doi: 10.1111/j.1600-0404.1975.tb01364.x. [DOI] [PubMed] [Google Scholar]
  25. Kurtzke J. F. A reassessment of the distribution of multiple sclerosis. Acta Neurol Scand. 1975 Feb;51(2):137–157. doi: 10.1111/j.1600-0404.1975.tb01365.x. [DOI] [PubMed] [Google Scholar]
  26. Kurtzke J. F., Bui-Quoc-Huong Multiple sclerosis in a migrant population: 2. Half-orientals immigrating in childhood. Ann Neurol. 1980 Sep;8(3):256–260. doi: 10.1002/ana.410080306. [DOI] [PubMed] [Google Scholar]
  27. Kurtzke J. F. Epidemiologic evidence for multiple sclerosis as an infection. Clin Microbiol Rev. 1993 Oct;6(4):382–427. doi: 10.1128/cmr.6.4.382. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Kurtzke J. F. Geography in multiple sclerosis. J Neurol. 1977 Apr 28;215(1):1–26. doi: 10.1007/BF00312546. [DOI] [PubMed] [Google Scholar]
  29. Kurtzke J. F., Gudmundsson K. R., Bergmann S. Multiple sclerosis in Iceland: 1. Evidence of a postwar epidemic. Neurology. 1982 Feb;32(2):143–150. doi: 10.1212/wnl.32.2.143. [DOI] [PubMed] [Google Scholar]
  30. Kurtzke J. F., Hyllested K. Multiple sclerosis in the Faroe Islands. II. Clinical update, transmission, and the nature of MS. Neurology. 1986 Mar;36(3):307–328. doi: 10.1212/wnl.36.3.307. [DOI] [PubMed] [Google Scholar]
  31. Kurtzke J. F., Hyllested K. Multiple sclerosis in the Faroe Islands. III. An alternative assessment of the three epidemics. Acta Neurol Scand. 1987 Nov;76(5):317–339. doi: 10.1111/j.1600-0404.1987.tb03590.x. [DOI] [PubMed] [Google Scholar]
  32. Kurtzke J. F., Hyllested K. Multiple sclerosis in the Faroe Islands: I. Clinical and epidemiological features. Ann Neurol. 1979 Jan;5(1):6–21. doi: 10.1002/ana.410050104. [DOI] [PubMed] [Google Scholar]
  33. Kurtzke J. F., Hyllested K. Validity of the epidemics of multiple sclerosis in the Faroe Islands. Neuroepidemiology. 1988;7(4):190–227. doi: 10.1159/000110154. [DOI] [PubMed] [Google Scholar]
  34. Kurtzke J. F., Kurland L. T., Goldberg I. D. Mortality and migration in multiple sclerosis. Neurology. 1971 Dec;21(12):1186–1197. doi: 10.1212/wnl.21.12.1186. [DOI] [PubMed] [Google Scholar]
  35. Lauer K. The risk of multiple sclerosis in the U.S.A. in relation to sociogeographic features: a factor-analytic study. J Clin Epidemiol. 1994 Jan;47(1):43–48. doi: 10.1016/0895-4356(94)90032-9. [DOI] [PubMed] [Google Scholar]
  36. Olerup O., Hillert J. HLA class II-associated genetic susceptibility in multiple sclerosis: a critical evaluation. Tissue Antigens. 1991 Jul;38(1):1–15. doi: 10.1111/j.1399-0039.1991.tb02029.x. [DOI] [PubMed] [Google Scholar]
  37. Poser C. M., Benedikz J., Hibberd P. L. The epidemiology of multiple sclerosis: the Iceland model. Onset-adjusted prevalence rate and other methodological considerations. J Neurol Sci. 1992 Sep;111(2):143–152. doi: 10.1016/0022-510x(92)90062-p. [DOI] [PubMed] [Google Scholar]
  38. Poser C. M., Hibberd P. L. Analysis of the 'epidemic' of multiple sclerosis in the Faroe Islands. II. Biostatistical aspects. Neuroepidemiology. 1988;7(4):181–189. doi: 10.1159/000110153. [DOI] [PubMed] [Google Scholar]
  39. Poser C. M., Hibberd P. L., Benedikz J., Gudmundsson G. Analysis of the 'epidemic' of multiple sclerosis in the Faroe Islands. I. Clinical and epidemiological aspects. Neuroepidemiology. 1988;7(4):168–180. doi: 10.1159/000110152. [DOI] [PubMed] [Google Scholar]
  40. Poser C. M. The dissemination of multiple sclerosis: a Viking saga? A historical essay. Ann Neurol. 1994 Dec;36 (Suppl 2):S231–S243. doi: 10.1002/ana.410360810. [DOI] [PubMed] [Google Scholar]
  41. Robertson N. P., Fraser M., Deans J., Clayton D., Walker N., Compston D. A. Age-adjusted recurrence risks for relatives of patients with multiple sclerosis. Brain. 1996 Apr;119(Pt 2):449–455. doi: 10.1093/brain/119.2.449. [DOI] [PubMed] [Google Scholar]
  42. Robertson N., Compston A. Surveying multiple sclerosis in the United Kingdom. J Neurol Neurosurg Psychiatry. 1995 Jan;58(1):2–6. doi: 10.1136/jnnp.58.1.2. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Rosati G. Descriptive epidemiology of multiple sclerosis in Europe in the 1980s: a critical overview. Ann Neurol. 1994 Dec;36 (Suppl 2):S164–S174. doi: 10.1002/ana.410360803. [DOI] [PubMed] [Google Scholar]
  44. Roullet E., Verdier-Taillefer M. H., Amarenco P., Gharbi G., Alperovitch A., Marteau R. Pregnancy and multiple sclerosis: a longitudinal study of 125 remittent patients. J Neurol Neurosurg Psychiatry. 1993 Oct;56(10):1062–1065. doi: 10.1136/jnnp.56.10.1062. [DOI] [PMC free article] [PubMed] [Google Scholar]
  45. Runmarker B., Andersen O. Pregnancy is associated with a lower risk of onset and a better prognosis in multiple sclerosis. Brain. 1995 Feb;118(Pt 1):253–261. doi: 10.1093/brain/118.1.253. [DOI] [PubMed] [Google Scholar]
  46. Runmarker B., Andersen O. Prognostic factors in a multiple sclerosis incidence cohort with twenty-five years of follow-up. Brain. 1993 Feb;116(Pt 1):117–134. doi: 10.1093/brain/116.1.117. [DOI] [PubMed] [Google Scholar]
  47. SUTHERLAND J. M. Observations on the prevalence of multiple sclerosis in Northern Scotland. Brain. 1956 Dec;79(4):635–654. doi: 10.1093/brain/79.4.635. [DOI] [PubMed] [Google Scholar]
  48. Sadovnick A. D., Armstrong H., Rice G. P., Bulman D., Hashimoto L., Paty D. W., Hashimoto S. A., Warren S., Hader W., Murray T. J. A population-based study of multiple sclerosis in twins: update. Ann Neurol. 1993 Mar;33(3):281–285. doi: 10.1002/ana.410330309. [DOI] [PubMed] [Google Scholar]
  49. Sadovnick A. D., Baird P. A., Ward R. H. Multiple sclerosis: updated risks for relatives. Am J Med Genet. 1988 Mar;29(3):533–541. doi: 10.1002/ajmg.1320290310. [DOI] [PubMed] [Google Scholar]
  50. Sadovnick A. D., Ebers G. C., Dyment D. A., Risch N. J. Evidence for genetic basis of multiple sclerosis. The Canadian Collaborative Study Group. Lancet. 1996 Jun 22;347(9017):1728–1730. doi: 10.1016/s0140-6736(96)90807-7. [DOI] [PubMed] [Google Scholar]
  51. Sawcer S., Jones H. B., Feakes R., Gray J., Smaldon N., Chataway J., Robertson N., Clayton D., Goodfellow P. N., Compston A. A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22. Nat Genet. 1996 Aug;13(4):464–468. doi: 10.1038/ng0896-464. [DOI] [PubMed] [Google Scholar]
  52. Seboun E., Robinson M. A., Doolittle T. H., Ciulla T. A., Kindt T. J., Hauser S. L. A susceptibility locus for multiple sclerosis is linked to the T cell receptor beta chain complex. Cell. 1989 Jun 30;57(7):1095–1100. doi: 10.1016/0092-8674(89)90046-9. [DOI] [PubMed] [Google Scholar]
  53. Sheremata W. A., Poskanzer D. C., Withum D. G., MacLeod C. L., Whiteside M. E. Unusual occurrence on a tropical island of multiple sclerosis. Lancet. 1985 Sep 14;2(8455):618–618. doi: 10.1016/s0140-6736(85)90621-x. [DOI] [PubMed] [Google Scholar]
  54. Sibley W. A., Bamford C. R., Clark K. Clinical viral infections and multiple sclerosis. Lancet. 1985 Jun 8;1(8441):1313–1315. doi: 10.1016/S0140-6736(85)92801-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
  55. Siemkowicz E. Multiple sclerosis and surgery. Anaesthesia. 1976 Nov;31(9):1211–1216. doi: 10.1111/j.1365-2044.1976.tb11973.x. [DOI] [PubMed] [Google Scholar]
  56. Siva A., Radhakrishnan K., Kurland L. T., O'Brien P. C., Swanson J. W., Rodriguez M. Trauma and multiple sclerosis: a population-based cohort study from Olmsted County, Minnesota. Neurology. 1993 Oct;43(10):1878–1882. doi: 10.1212/wnl.43.10.1878. [DOI] [PubMed] [Google Scholar]
  57. Walter M. A., Gibson W. T., Ebers G. C., Cox D. W. Susceptibility to multiple sclerosis is associated with the proximal immunoglobulin heavy chain variable region. J Clin Invest. 1991 Apr;87(4):1266–1273. doi: 10.1172/JCI115128. [DOI] [PMC free article] [PubMed] [Google Scholar]
  58. Weinshenker B. G., Bass B., Rice G. P., Noseworthy J., Carriere W., Baskerville J., Ebers G. C. The natural history of multiple sclerosis: a geographically based study. 2. Predictive value of the early clinical course. Brain. 1989 Dec;112(Pt 6):1419–1428. doi: 10.1093/brain/112.6.1419. [DOI] [PubMed] [Google Scholar]
  59. Weinshenker B. G., Rice G. P., Noseworthy J. H., Carriere W., Baskerville J., Ebers G. C. The natural history of multiple sclerosis: a geographically based study. 3. Multivariate analysis of predictive factors and models of outcome. Brain. 1991 Apr;114(Pt 2):1045–1056. doi: 10.1093/brain/114.2.1045. [DOI] [PubMed] [Google Scholar]
  60. Wood N. W., Sawcer S. J., Kellar-Wood H. F., Holmans P., Clayton D., Robertson N., Compston D. A. Susceptibility to multiple sclerosis and the immunoglobulin heavy chain variable region. J Neurol. 1995 Oct;242(10):677–682. doi: 10.1007/BF00866919. [DOI] [PubMed] [Google Scholar]
  61. Wood N. W., Sawcer S. J., Kellar-Wood H. F., Holmans P., Clayton D., Robertson N., Compston D. A. The T-cell receptor beta locus and susceptibility to multiple sclerosis. Neurology. 1995 Oct;45(10):1859–1863. doi: 10.1212/wnl.45.10.1859. [DOI] [PubMed] [Google Scholar]
  62. Worthington J., Jones R., Crawford M., Forti A. Pregnancy and multiple sclerosis--a 3-year prospective study. J Neurol. 1994 Feb;241(4):228–233. doi: 10.1007/BF00863773. [DOI] [PubMed] [Google Scholar]

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