Abstract
The concentration of oestrone in the cerebrospinal fluid (CSF) from obese young women with pseudotumour cerebri was much greater than predicted and found in normal subjects. Each woman with pseudotumour cerebri, and a high level of CSF oestrone and a CSF protein less than 0·2 g/l, had clinical improvement when treated with an 800 calorie/day diet and dexamethasone 2 mg/day.
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- Bäckström T., Carstensen H., Södergard R. Concentration of estradiol, testosterone and progesterone in cerebrospinal fluid compared to plasma unbound and total concentrations. J Steroid Biochem. 1976 Jun-Jul;7(6-7):469–472. doi: 10.1016/0022-4731(76)90114-x. [DOI] [PubMed] [Google Scholar]
- David G. F., Kumar T. C. Transfer of steroidal hormones from blood to the cerebrospinal fluid in the Rhesus monkey. Neuroendocrinology. 1974;14(2):114–120. doi: 10.1159/000122251. [DOI] [PubMed] [Google Scholar]
- Donaldson J. O., Binstock M. L. Pseudotumor cerebri in an obese woman with Turner syndrome. Neurology. 1981 Jun;31(6):758–760. doi: 10.1212/wnl.31.6.758. [DOI] [PubMed] [Google Scholar]
- Donaldson J. O. Pathogenesis of pseudotumor cerebri syndromes. Neurology. 1981 Jul;31(7):877–880. doi: 10.1212/wnl.31.7.877. [DOI] [PubMed] [Google Scholar]
- Marynick S. P., Havens W. W., 2nd, Ebert M. H., Loriaux D. L. Studies on the transfer of steroid hormones across the blood-cerebrospinal fluid barrier in the Rhesus Monkey. Endocrinology. 1976 Aug;99(2):400–405. doi: 10.1210/endo-99-2-400. [DOI] [PubMed] [Google Scholar]
- Marynick S. P., Smith G. B., Ebert M. H., Loriaux D. L. Studies on the transfer of steroid hormones across the blood-cerebrospinal fluid barrier in the rhesus monkey. II. Endocrinology. 1977 Aug;101(2):562–567. doi: 10.1210/endo-101-2-562. [DOI] [PubMed] [Google Scholar]
- STRUCK H. UBER DIE BINDUNG VON OSTRON, 17-BETA-OSTRADIOL UND OSTRIOL AN PROTEINE IN VITRO. Hoppe Seylers Z Physiol Chem. 1963;333:89–98. doi: 10.1515/bchm2.1963.333.1.89. [DOI] [PubMed] [Google Scholar]