Abstract
Two patients are described in whom computerised tomography revealed contrast-enhanced lesions in the early stages of multiple sclerosis. Such lesions may be differentiated from tumours by their transient nature, lack of space-occupying effect, and localisation in the white matter. Contrast enhancement in demyelinating disease is probably related to local breakdown of the blood-brain barrier.
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- BROMAN T. BLOOD-BRAIN BARRIER DAMAGE IN MULTIPLE SCLEROSIS SUPRAVITAL TEST-OBSERVATIONS. Acta Neurol Scand Suppl. 1964;40:SUPPL 10–10:24. doi: 10.1111/j.1600-0404.1964.tb04718.x. [DOI] [PubMed] [Google Scholar]
- Cala L. A., Mastaglia F. L. Computerised axial tomography in multiple sclerosis. Lancet. 1976 Mar 27;1(7961):689–689. doi: 10.1016/s0140-6736(76)92797-5. [DOI] [PubMed] [Google Scholar]
- Cole M., Ross R. J. Plaque of multiple sclerosis seen on computerized transaxial tomogram. Neurology. 1977 Sep;27(9):890–891. doi: 10.1212/wnl.27.9.890. [DOI] [PubMed] [Google Scholar]
- Gado M. H., Phelps M. E., Coleman R. E. An extravascular component of contrast enhancement in cranial computed tomography. Part II. Contrast enhancement and the blood-tissue barrier. Radiology. 1975 Dec;117(3 Pt 1):595–597. doi: 10.1148/117.3.595. [DOI] [PubMed] [Google Scholar]
- Gyldensted C. Computer tomography of the brain in multiple sclerosis. A radiological study of 110 patients with special reference to demonstration of cerebral plaques. Acta Neurol Scand. 1976 May;53(5):386–389. doi: 10.1111/j.1600-0404.1976.tb04356.x. [DOI] [PubMed] [Google Scholar]
- Gyldensted C. Computer tomography of the cerebrum in multiple sclerosis. Neuroradiology. 1976 Oct 27;12(1):33–42. doi: 10.1007/BF00344224. [DOI] [PubMed] [Google Scholar]
- Link H., Müller R. Immunoglobulins in multiple sclerosis and infections of the nervous system. Arch Neurol. 1971 Oct;25(4):326–344. doi: 10.1001/archneur.1971.00490040052007. [DOI] [PubMed] [Google Scholar]