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. 2024 May 30;24:410. doi: 10.1186/s12888-024-05809-w

The relationship between childhood psychological abuse and depression in college students: a moderated mediation model

Yang Liu 1,#, Qingxin Shen 1,#, Liangfan Duan 1,#, Lei Xu 1,2, Yongxiang Xiao 1, Tiancheng Zhang 1,
PMCID: PMC11141024  PMID: 38816793

Abstract

Background

Childhood psychological abuse (CPA) are highly correlated with depression among college students, but the underlying mechanisms between variables need further exploration. This study aims to investigate internet addiction as a mediating factor and alexithymia as a moderating factor, in order to further elucidate the potential risk factors between CPA and depression among college students.

Methods

A self-report survey was conducted among 1196 college students from four universities in three provinces in China. The survey included measures of CPA, internet addiction, alexithymia, and depression. Descriptive and correlational analyses were performed on these variables, and a moderated mediation model was constructed.

Results

CPA was positively correlated with depression among college students, as well as internet addiction with alexithymia. Internet addiction partially mediated the relationship between CPA and depression among college students, while alexithymia strengthened the relationships among the paths in the moderated mediation model.

Conclusion

This study provides further insights into the psychological mechanisms underlying the relationship between CPA and depression among college students. Internet addiction serves as a mediating factor in this relationship, while alexithymia may enhance the strength of the relationships among the three variables.

Keywords: Childhood psychological abuse, Depression, Alexithymia, Internet addiction, College students

Introduction

Depression is a highly prevalent psychological disorder among young people, characterized by symptoms such as sadness, lack of energy, and despair [1]. Over the past decade, the incidence of depression has been continuously increasing [2, 3]. Studies show that the prevalence of depression among Chinese university students exceeds 25% [4, 5], and the global incidence rate is close to 30% [6]. Individuals with depression exhibit a variety of complex negative physical and mental manifestations [7]. Feelings of worthlessness, hopelessness, and self-blame are strong emotional experiences among depressed individuals [8]. Major cognitive impairments displayed by these individuals include emotional dysregulation, cognitive biases, difficulties in attention and memory, and inhibitory dysfunction [9, 10]. Similarly, outward behaviors manifest a range of negative patterns, such as social withdrawal [11], sleep disturbances [12], and abnormal changes in appetite [13]. These physical and mental manifestations further deepen the severity of depression [14]. Additionally, the etiology of depression is complex, with early-life stress being a significant risk factor [15], and that is often associated with adverse childhood experiences [16], such as childhood abuse. Childhood abuse has a close relationship with depression [1720], and studies have found that among the subtypes of childhood abuse that childhood psychological abuse (CPA) is most closely related to depression [18, 21]. Given the significant harm of depression, social attention, and its strong association with CPA, this study strongly needs to explore the underlying mechanisms between the two, in order to intervene and prevent timely and predict the impact of CPA on individual depression.

CPA refers to inappropriate psychological parenting behavior that guardians continuously and repeatedly adopt during childhood, which has an adverse effect on individuals' growth [22]. Due to its particular nature, the detection rate of CPA is quite high in different countries [23, 24]. Abuse and neglect are two subtypes of CPA that are increasingly accepted by scholars in related studies. Longitudinal studies have found that parents' psychological neglect predicts future depression in adolescents [25]. In addition, research has found that among the classifications of childhood abuse, the correlation between psychological abuse and depression is the highest [18]. Based on the above review, this study hypothesized that CPA can significantly predict the occurrence of depression in college students.

Individuals who have experienced CPA often encounter emotional distress. Faced with such distress, they may be at an increased risk of engaging in hazardous behaviors, such as internet addiction, as these online activities may serve as a coping mechanism to alleviate negative emotions [26]. Without intervention, this reliance on the internet can form a cyclical pattern, potentially leading to internet addiction. Internet addiction is characterized by an excessive, problematic, and compulsive engagement in behaviors related to internet use [27, 28]. Research indicates that among the various subtypes of childhood maltreatment, CPA has the strongest association with internet addiction [29]. CPA can significantly predict individuals internet addiction, and internet addiction has been found to mediate the relationship between CPA and suicidal internet addiction behaviors [30]. In discussions that integrate the relationship between childhood maltreatment and internet addiction, CPA is highlighted as a particularly salient predictor [31]. Consistent with the social compensation theory [32], CPA may lead individuals to seek emotional fulfillment through online interactions. Furthermore, there is a recognized association between internet addiction and depression. Research has found a strong correlation between internet addiction and depression [33], with internet addiction being a significant predictor of depression [34]. Longitudinal studies have shown a significant bidirectional relationship between internet addiction and depression among college students [35]. The displacement hypothesis [36] suggests that excessive internet use may impede real-life social interactions, reduce well-being, and deepen depression. Depression can also intensify the level of internet addiction, creating a vicious cycle and leading to a "rich get richer" scenario [37]. Based on this evidence, this study posits that CPA can significantly predict internet addiction among college students, which in turn can significantly predict depression.

However, when individuals possess certain traits, the relationships among the variables mentioned above may be strengthened, exacerbating negative behaviors or psychological outcomes. Among these variables, the level of alexithymia is one of the more important ones. Alexithymia is a stable personality trait [38], characterized by limited ability to understand one's own feelings and others' emotions, inadequate emotion regulation in interpersonal interactions [39], difficulty in recognizing emotions, describing emotions, and an externally oriented thinking style [40]. Alexithymia, due to emotional dysregulation, can lead to the intensification of negative emotions such as anxiety and depression [41], and inaccurate attention and expression of emotions may result in poor interpersonal relationships [42], thereby increasing individuals' psychological burden. To escape or alleviate such negative psychological states, the internet on mobile phones provides an easily accessible avenue [4245]. According to the alexithymia stress hypothesis, individuals with high levels of alexithymia often find themselves in a state of stress due to their inadequate understanding and recognition of their own and others' emotions [46], which further predicts severe negative psychological states [47]. Therefore, based on the aforementioned review, it is evident that alexithymia may enhance the relationship between CPA, internet addiction, and depression discussed in this study, further exacerbating the degree of negative psychological and behavioral outcomes. Additionally, individuals with alexithymic characteristics not only neglect emotions [48], but they may also have a generalized impairment in perceiving internal bodily sensations (interoception) compared to individuals with lower levels of alexithymia [49], as demonstrated by various studies on the accuracy of perceiving heart rate [50, 51], delayed healthcare seeking for illnesses [52], and unstable substance intake [53], among others. Based on these features, individuals with high levels of alexithymia tend to overlook their own discomfort symptoms even when they excessively use the internet [54, 55] due to their lower sensory perception. Therefore, we hypothesize that alexithymia moderates the relationships among CPA, internet addiction, and depression mediated by various paths.

In summary, previous research strongly indicates the relationship and predictive role of CPA and depression, but these areas are relatively understudied among Chinese university students. To further supplement research in this field and explore underlying psychological mechanisms, this study introduces the mediating variable of internet addiction and the moderating variable of alexithymia. Therefore, this study constructs a hypothetical path model (see Fig. 1).

Fig. 1.

Fig. 1

Hypothesized a moderated and mediation model

Methods

Participants

This cross-sectional survey was conducted in October 2023 among Chinese university students from four universities in Hunan Province, Hubei Province, and Guangxi Province. Prior to distribution, the researchers delivered a presentation to all participants, informing them of the main content and confidentiality of the survey data, as well as its ultimate purpose. The electronic questionnaires were distributed on a class basis, with an informed consent statement attached to the questionnaire's cover page. Participants could proceed with the survey only after choosing to agree, while those who declined would be directed to an exit page. Informed consent was obtained from all the participants. The survey was anonymous and voluntary, and it could be completed within 20 min. Prior to commencement, this study obtained approval from the Biomedicine Ethics Committee of Jishou University. We confirm that all the procedure is in accordance with the relevant guidelines and regulations such as the declaration of Helsinki. A total of 1352 students completed the survey, and after excluding respondents with excessively short response times or patterns in their answers, valid data from 1196 participants (496 males, 700 females) were ultimately obtained, with an average age of 18.69 years (SD = 1.07).

Measures

Childhood psychological abuse (CPA)

The measurement of CPA utilized the psychological abuse and neglect subscales from the Short Childhood Trauma Questionnaire (SCTQ) [56]. Each subscale included 5 items, scored on a Likert scale of 1 (never) to 5 (always), assessing the experiences of participants before the age of 17. An example item from the scale is: “Someone in my family said insulting or sad things to me”. Higher scores indicated higher levels of CPA. In this study, the Cronbach's α for the sample was 0.878.

Depression

Depression among college students was measured using the depression subscale from the Chinese version of the Depression Anxiety Stress Scale (DASS-21) [57]. The subscale comprised 7 items, scored on a Likert scale of 1 (strongly disagree) to 4 (strongly agree), assessing the level of depression experienced by participants. An example item from the scale is: “I can't be enthusiastic about anything”. Higher scores indicated more severe depression. In this study, the Cronbach's α for the sample was 0.906.

Internet addiction

Internet addiction among college students was measured using the Problematic Social Media Use (PSMU) Scale [58]. The scale comprised 8 items, scored on a Likert scale of 1 (not at all) to 5 (completely), assessing the level of internet addiction experienced by participants. An example item from the scale is: “Using social networking sites distracts me from my studies”. Higher scores indicated more severe internet addiction. In this study, the Cronbach's α for the sample was 0.857.

Alexithymia

The Toronto Alexithymia Scale (TAS-20) was used to assess the level of alexithymia among college students [59]. The scale comprised 20 items, scored on a Likert scale of 1 (totally disagree) to 5 (totally agree), assessing the level of alexithymia experienced by participants. An example item from the scale is: “I am often confused about what emotion I am feeling”. Higher scores indicated more severe alexithymia. In this study, the Cronbach's α for the sample was 0.804.

Covariates

Considering the potential influence of demographic variables, such as gender and age [31, 60], on the analysis results, we controlled for these variables in our analysis.

Statistical analyses

All statistical analyses were conducted using SPSS 26.0 software. Firstly, we checked for methodological biases to evaluate the potential bias resulting from self-report questionnaires. Before initiating the data analysis, we assessed the normality of our data using the Shapiro–Wilk test. According to Kim's proposal, data exhibiting an absolute skewness value below 2 and an absolute kurtosis value below 7 may be deemed to approximate a normal distribution [61]. In our study, we found that the variables CPA, depression, internet addiction, and alexithymia were normally distributed. For variables conforming to a normal distribution, descriptive analysis was conducted using the mean and standard deviation (Sd), while Pearson's correlation analysis was employed to assess the relationships among them. Then, we standardized the data of the main variables before conducting the analyses. Finally, to test our hypotheses, we used the PROCESS macro (Mode 4 and Model 59) in SPSS to analyze the relationships between variables [62]. The PROCESS macro was based on a bootstrapping method with 5000 resamples to estimate the model testing and 95% confidence intervals (95% CI), and a relationship was considered significant when the 95% CI did not include 0. Gender and age were considered as covariates in the analyses, and the significance level was set at α = 0.05.

Results

Harman’s single factor test and normality test

Harman's single-factor test was used to examine the impact of common method bias. The analysis results showed that there were 2 factors with eigenvalues greater than 1. Without rotating the principal component factors, the explanatory rate of the first factor was 35.55%, which is lower than the recommended threshold of 40% [63]. Therefore, this study did not encounter severe common method bias. Upon assessing normality for our principal variables, all variables exhibited absolute skewness values below 2 and absolute kurtosis values below 7. Consequently, parametric tests were employed for all subsequent analyses.

Descriptive analyses

The results of Table 1 show that CPA (t = 2.62, p < 0.001), depression (t = 2.32, p < 0.05) and Internet addiction (t = -2.17, p < 0.05) are different between genders and reach statistical significance.

Table 1.

Descriptive results

Variables Total (n = 1196) Male (n = 496) Female (n = 700) Male vs. Female
Mean Sd Mean Sd Mean Sd t
CPA 20.03 7.01 20.66 6.97 19.57 7.16 2.62***
Depression 12.48 4.33 12.83 4.62 13.23 4.09 2.32*
Internet addiction 22.14 6.29 21.67 6.72 22.47 5.96 -2.17*
Alexithymia 53.02 9.75 53.08 9.88 52.98 9.66 0.18

CPA Childhood psychological abuse

*p < 0.05

***p < 0.001

Correlational analyses

Table 2 presents the Pearson correlation data between the variables of interest. CPA was significantly positively correlated with college students' internet addiction (r = 0.240, p < 0.001), depression (r = 0.481, p < 0.001), and alexithymia (r = 0.322, p < 0.001). College students' internet addiction was significantly positively correlated with depression (r = 0.384, p < 0.001) and alexithymia (r = 0.262, p < 0.001). Depression was significantly negatively correlated with college students' alexithymia (r = 0.461, p < 0.001).

Table 2.

Correlational analyses (n = 1196)

Age CPA Internet addiction Depression Alexithymia
Age -
CPA 0.188*** -
Internet addiction 0.035 0.240*** -
Depression 0.129*** 0.481*** 0.384*** -
Alexithymia 0.018 0.322*** 0.262*** 0.461*** -

***p < 0.001

Mediation analysis

Table 3 presents the results showing that, after controlling for gender and age, CPA can significantly predict depression in college students (β = 0.473, SE = 0.026, p < 0.001). When internet addiction was included as a mediator variable, CPA continued to significantly predict depression in college students (β = 0.402, SE = 0.025, p < 0.001). Additionally, upon testing the mediation model, it was found that CPA significantly predicts internet addiction in college students (β = 0.245, SE = 0.029, p < 0.001), and internet addiction also significantly predicts depression (β = 0.290, SE = 0.025, p < 0.001).

Table 3.

Mediation model test

Variables Depression Internet addiction Depression
β SE t β SE t β SE t
Gender -0.049 0.053 -0.921 0.170 0.059 2.889** -0.098 0.051 -1.940
Age 0.032 0.025 1.269 0.009 0.028 0.337 0.029 0.024 1.225
CPA 0.473 0.026 18.300*** 0.245 0.029 8.576*** 0.402 0.025 15.927***
Internet addiction 0.290 0.025 11.660***
R2 0.233 0.064 0.312
F 120.941*** 27.351*** 134.967***

**p < 0.01

***p < 0.001

Moderated and mediation analysis

After controlling for covariates, the moderated mediation model analysis revealed that the predictive effects of all paths in the mediation model remained significantly present (CPA predicting depression:β = 0.322, SE = 0.025, p < 0.001; CPA predicting internet addiction:β = 0.180, SE = 0.030, p < 0.001; Internet addiction predicting depression:β = 0.223, SE = 0.024, p < 0.001). Additionally, alexithymia significantly predicted college students' internet addiction (β = 0.201, SE = 0.029, p < 0.001) and depression (β = 0.281, SE = 0.025, p < 0.001). Lastly, the interaction term between alexithymia and CPA significantly predicted college students' internet addiction (β = 0.072, SE = 0.027, p < 0.01) and depression (β = 0.071, SE = 0.023, p < 0.01), and the interaction term between internet addiction and alexithymia significantly predicted college students' depression (β = 0.060, SE = 0.022, p < 0.01). Refer to Table 4, Figs. 2 and 3 for details.

Table 4.

Moderated and mediation analysis

Internet addiction Depression
β SE t β SE t
Gender 0.157 0.058 2.725** -0.101 0.047 -2.140*
Age 0.018 0.027 0.654 0.040 0.022 1.817
CPA (A) 0.180 0.030 6.100*** 0.322 0.025 13.087***
Alexithymia (B) 0.201 0.029 6.921*** 0.281 0.025 11.390***
A X B 0.072 0.027 2.728** 0.071 0.023 3.051**
Internet addiction (C) 0.223 0.024 9.370***
B X C 0.060 0.022 2.707**
R2 0.108 0.400
F 28.736*** 113.278***

*p < 0.05

**p < 0.01

***p < 0.001

Fig. 2.

Fig. 2

Moderated and mediation model

Fig. 3.

Fig. 3

Simple slope plot

Discussion

This study examines the relationships between CPA, internet addiction, depression, and alexithymia among college students. The findings reveal positive correlations between CPA, internet addiction, depression, and alexithymia, all of which are statistically significant. After controlling for demographic variables, internet addiction is found to mediate the relationship between CPA and depression in college students, while alexithymia moderates this relationship, confirming our initial hypothesis.

Our study confirms the positive correlation between CPA and depression in college students, which is consistent with previous research [18, 31]. Studies conducted in China have shown that childhood abuse is relatively common [64], with emotional abuse being the most prevalent type [65, 66]. Almost all types of childhood abuse are associated with mental health problems [20, 23, 67, 68], increasing the risk of various adversities in individuals' later lives [23, 69, 70], with psychological abuse being particularly prominent [31, 68], even predicting somatic symptoms in patients with severe depression [71]. Furthermore, research has found that CPA becomes the sole predictor of adolescent depression when controlling for other types of abuse, and early psychological abuse has a greater impact on depression [72]. Children who receive warm, rule-following, and well-bounded care from parents perform better in various aspects, including mental health [73]. On the other hand, children who experience psychological abuse from caregivers, in a state of invisible stress similar to social isolation, are more likely to develop depression, anxiety, and even aggressive behaviors [74].

Our study supports the hypothesis that internet addiction mediates the relationship between CPA and depression in college students, which is consistent with other similar studies [29]. Previous research has found a strong association between CPA and internet addiction among young people [30, 31, 75, 76]. The relationship between internet addiction and depression has also been strongly supported [77], including in studies conducted in China [35]. According to the explanations of social control theory [78] and compensatory internet use theory [32], CPA seems to indicate unfavorable family support environments for adolescents, leading them to seek support from the virtual online world and developing internet addiction. It was found that adolescents who were addicted to the internet at baseline were more likely to develop depression in the future [77], which is also true in other studies [79]. Adolescents addicted to the internet often face greater stress, making them more prone to depression [80].

As previously hypothesized, alexithymia strengthens the relationships between all pathways. Individuals with alexithymia have difficulty understanding their own and others' emotions and are unable to regulate their emotions appropriately in daily interpersonal interactions [39], leading to an exacerbation of negative emotions [41]. Additionally, based on the explanations of general strain theory [81] and compensatory internet use theory [82], individuals with alexithymia feel stressed in dealing with interpersonal relationships [83]. Under this negative emotional state, in order to meet the needs of interpersonal communication and escape from the pressure of reality, they naturally choose the online world, which further leads to the development and intensification of internet addiction. However, alexithymia's "dullness" towards one's own feelings is not limited to emotions but can also extend to the perception of internal sensations [49]. Brain regions associated with these internal sensations include the anterior insula and anterior cingulate cortex [84, 85], which not only play a role in non-emotional interoception but also have significant implications for individuals' emotional processing [86, 87]. Studies have found structural abnormalities in these brain regions in individuals with alexithymia [8890]. It is possible that individuals with severe pain and fatigue continue to use the internet despite their condition, further exacerbating their involvement in negative psychological and behavioral patterns. Therefore, high levels of alexithymia strengthen the relationships between CPA, internet addiction, and depression, which aligns with the expectations of this study.

In conclusion, our study further contributes to understanding the relationship between CPA and depression in college students, as well as the mediating role of internet addiction and the moderating role of alexithymia. These findings are not commonly seen in previous research. However, the study has several limitations. Firstly, the accuracy of self-reported CPA data may be insufficient as it involves retrospective self-reporting. Secondly, the representativeness of the sample may be inadequate as we only selected local colleges from a few provinces in China, with most of the students being locals. Future studies could increase the diversity of the sample. Lastly, due to the cross-sectional nature of the study, the causal relationships between variables are challenged. Therefore, future research could explore causal relationships based on longitudinal tracking.

Conclusion

This study discusses the relationships between CPA, internet addiction, depression, and alexithymia among college students, confirming the mediating role of internet addiction and the moderating role of alexithymia between CPA and depression. Individuals, families, schools, and society should pay attention to the negative impacts caused by CPA, especially for individuals with high levels of alexithymia.

Acknowledgements

Zirui Zhou, Shiju Zhu.

Authors’ contributions

Author statement: Yang Liu12345, Qingxin Sheng12345, Liangfan Duan12345, Lei Xu156, Yongxiang Xiao15, Tiancheng Zhang156. 1 Conceptualization; 2 Methodology; 3 Data curation; 4 Writing—Original Draft; 5 Writing—Review &; Editing; 6 Funding acquisition.

Funding

Not applicable.

Availability of data and materials

The datasets generated and/or analysed during the current study are not publicly available due [our experimental team's policy] but are available from the corresponding author on reasonable request.

Declarations

Ethics approval and consent to participate

The study was approved by the Biomedicine Ethics Committee of Jishou University before the initiation of the project (Grant number: JSDX-2023–0034). And informed consent was obtained from the participants before starting the program.

Consent for publication

Not applicable.

Competing interests

The authors declare no competing interests.

Footnotes

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Yang Liu, Qingxin Shen and Liangfan Duan these authors have contributed equally to this work and share first authorship.

References

  • 1.Clark MS, Jansen KL, Cloy JA. Treatment of childhood and adolescent depression. Am Fam Physician. 2012;86(5):442–448. [PubMed] [Google Scholar]
  • 2.Moreno-Agostino D, Wu Y, Daskalopoulou C, Hasan MT, Huisman M, Prina M. Global trends in the prevalence and incidence of depression:a systematic review and meta-analysis. J Affect Disord. 2021;281:235–243. doi: 10.1016/j.jad.2020.12.035. [DOI] [PubMed] [Google Scholar]
  • 3.Twenge JM, Cooper AB, Joiner TE, Duffy ME, Binau SG. Age, period, and cohort trends in mood disorder indicators and suicide-related outcomes in a nationally representative dataset, 2005–2017. J Psychopathol Clin Sci. 2019;128(3):185–199. doi: 10.1037/abn0000410. [DOI] [PubMed] [Google Scholar]
  • 4.Gao L, Xie Y, Jia C, Wang W. Prevalence of depression among Chinese university students: a systematic review and meta-analysis. Sci Rep. 2020;10(1):15897. doi: 10.1038/s41598-020-72998-1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 5.Zeng W, Chen R, Wang X, Zhang Q, Deng W. Prevalence of mental health problems among medical students in China. Medicine. 2019;98(18):e15337. doi: 10.1097/MD.0000000000015337. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 6.Ibrahim AK, Kelly SJ, Adams CE, Glazebrook C. A systematic review of studies of depression prevalence in university students. J Psychiatr Res. 2013;47(3):391–400. doi: 10.1016/j.jpsychires.2012.11.015. [DOI] [PubMed] [Google Scholar]
  • 7.Guerrera CS, Platania GA, Boccaccio FM, Sarti P, Varrasi S, Colliva C, et al. The dynamic interaction between symptoms and pharmacological treatment in patients with major depressive disorder: the role of network intervention analysis. BMC Psychiatry. 2023;23(1):885. doi: 10.1186/s12888-023-05300-y. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8.Harrison P, Lawrence AJ, Wang S, Liu S, Xie G, Yang X, et al. The psychopathology of worthlessness in depression. Front Psychiatr. 2022;13:818542. doi: 10.3389/fpsyt.2022.818542. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 9.Kircanski K, Joormann J, Gotlib IH. Cognitive aspects of depression Wiley interdisciplinary reviews. Cognitive Sci. 2012;3(3):301–313. doi: 10.1002/wcs.1177. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 10.Gotlib IH, Joormann J. Cognition and depression: current status and future directions. Annu Rev Clin Psychol. 2010;6:285–312. doi: 10.1146/annurev.clinpsy.121208.131305. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 11.Teo AR, Nelson S, Strange W, Kubo H, Katsuki R, Kurahara K, et al. Social withdrawal in major depressive disorder: a case-control study of hikikomori in japan. J Affect Disord. 2020;274:1142–1146. doi: 10.1016/j.jad.2020.06.011. [DOI] [PubMed] [Google Scholar]
  • 12.Sun X, Zheng B, Lv J, Guo Y, Bian Z, Yang L, et al. Sleep behavior and depression: Findings from the China Kadoorie Biobank of 0.5 million Chinese adults. J Affect Dis. 2018;229:120–124. doi: 10.1016/j.jad.2017.12.058. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13.Simmons WK, Burrows K, Avery JA, Kerr KL, Bodurka J, Savage CR, et al. Depression-related increases and decreases in appetite: dissociable patterns of aberrant activity in reward and interoceptive neurocircuitry. Am J Psychiatry. 2016;173(4):418–428. doi: 10.1176/appi.ajp.2015.15020162. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 14.Kupferberg A, Hasler G. The social cost of depression: Investigating the impact of impaired social emotion regulation, social cognition, and interpersonal behavior on social functioning. Journal of Affective Disorders Reports. 2023;14:100631. doi: 10.1016/j.jadr.2023.100631. [DOI] [Google Scholar]
  • 15.Hammen C. Risk factors for depression: an autobiographical review. Annu Rev Clin Psychol. 2018;14:1–28. doi: 10.1146/annurev-clinpsy-050817-084811. [DOI] [PubMed] [Google Scholar]
  • 16.McLaughlin KA, Conron KJ, Koenen KC, Gilman SE. Childhood adversity, adult stressful life events, and risk of past-year psychiatric disorder: a test of the stress sensitization hypothesis in a population-based sample of adults. Psycholog Med. 2010;40(10):1647–1658. doi: 10.1017/S0033291709992121. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 17.Chang JJ, Ji Y, Li YH, Yuan MY, Su PY. Childhood trauma and depression in college students: Mediating and moderating effects of psychological resilience. Asian J Psychiatr. 2021;65:102824. doi: 10.1016/j.ajp.2021.102824. [DOI] [PubMed] [Google Scholar]
  • 18.Pirdehghan A, Vakili M, Rajabzadeh Y, Puyandehpour M, Aghakoochak A. Child abuse and mental disorders in Iranian adolescents. Iranian J Pediatr. 2016;26(2):e3839. doi: 10.5812/ijp.3839. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 19.Wang ZC. Childhood abuse and adolescent depression: moderating roles of social support and friendship quality. Soc Behav Personality. 2023;51(1):1. doi: 10.2224/sbp.12136. [DOI] [Google Scholar]
  • 20.VanMeter F, Nivison MD, Englund MM, Carlson EA, Roisman GI. Childhood abuse and neglect and self-reported symptoms of psychopathology through midlife. Dev Psychol. 2021;57(5):824–836. doi: 10.1037/dev0001169. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 21.Zhou X, Zhen R. How do physical and emotional abuse affect depression and problematic behaviors in adolescents? The roles of emotional regulation and anger. Child Abuse Negl. 2022;129:105641. doi: 10.1016/j.chiabu.2022.105641. [DOI] [PubMed] [Google Scholar]
  • 22.McCrory EJ, Gerin MI, Viding E. Annual research review: childhood maltreatment, latent vulnerability and the shift to preventative psychiatry - the contribution of functional brain imaging. J Child Psychol Psychiatry. 2017;58(4):338–357. doi: 10.1111/jcpp.12713. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 23.Diaz A, Shankar V, Nucci-Sack A, Linares LO, Salandy A, Strickler HD, et al. Effect of child abuse and neglect on risk behaviors in inner-city minority female adolescents and young adults. Child Abuse Negl. 2020;101:104347. doi: 10.1016/j.chiabu.2019.104347. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 24.Liang JY, Zhuo YS, Li XR, Qin F. Structural equation model of childhood psychological abuse and neglect,psychologica resilience, life satisfaction and mobile phone addiction in medical students. Occupation and Health. 2020;19:36–19. [Google Scholar]
  • 25.Christ SL, Kwak YY, Lu T. The joint impact of parental psychological neglect and peer isolation on adolescents' depression. Child Abuse Negl. 2017;69:151–162. doi: 10.1016/j.chiabu.2017.04.015. [DOI] [PubMed] [Google Scholar]
  • 26.Suh JJ, Ruffins S, Robins CE, Albanese MJ, Khantzian EJ. Self-medication hypothesis: connecting affective experience and drug choice. Psychoanal Psychol. 2008;25(3):518–532. doi: 10.1037/0736-9735.25.3.518. [DOI] [Google Scholar]
  • 27.Holden C. 'Behavioral' Addictions: Do They Exist? Science (New York, N.Y.) 2001;294(5544):980–982. doi: 10.1126/science.294.5544.980. [DOI] [PubMed] [Google Scholar]
  • 28.Young KS, Rogers RC. The relationship between depression and Internet addiction. Cyberpsychol Behav. 1998;1(1):25–28. doi: 10.1089/cpb.1998.1.25. [DOI] [Google Scholar]
  • 29.Yang M, Sheng XL, Ge ML, Zhang L, Huang C, Cui S, et al. Childhood trauma and psychological sub-health among Chinese adolescents: the mediating effect of Internet addiction. BMC Psychiatry. 2022;22(1):762. doi: 10.1186/s12888-022-04384-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 30.Peng C, Wang MN, Cheng JH, Tan YF, Huang YX, Rong FJ, et al. Mediation of Internet addiction on association between childhood maltreatment and suicidal behaviours among Chinese adolescents. Epidemiol Psychiatric Sci. 2021;30:e64. doi: 10.1017/S2045796021000524. [DOI] [Google Scholar]
  • 31.Dong X, Zhang RX, Zhornitsky S, Le TM, Wang WY, et al. Depression mediates the relationship between childhood trauma and internet addiction in female but not male chinese adolescents and young adults. J Clin Med. 2021;10(21):5015. doi: 10.3390/jcm10215015. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 32.Valkenburg PM, Peter J. Social consequences of the internet for adolescents: a decade of research. Curr Dir Psychol Sci. 2009;18(1):1–5. doi: 10.1111/j.1467-8721.2009.01595.x. [DOI] [Google Scholar]
  • 33.Saikia AM, Das J, Barman P, Bharali MD. Internet Addiction and its relationships with depression, anxiety, and stress in urban adolescents of Kamrup District, Assam. J Family Commun Med. 2019;26(2):108–112. doi: 10.4103/jfcm.JFCM_93_18. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 34.Zhao M, Huang YL, Wang JY, Feng J, Zhou B. Internet addiction and depression among Chinese adolescents: anxiety as a mediator and social support as a moderator. Psychol Health Med. 2023;28(8):2315–2328. doi: 10.1080/13548506.2023.2224041. [DOI] [PubMed] [Google Scholar]
  • 35.Yang X, Guo WJ, Tao YJ, Meng YJ, Wang HY, Li XJ, et al. A bidirectional association between internet addiction and depression: a large-sample longitudinal study among Chinese university students. J Affect Disord. 2022;299:416–424. doi: 10.1016/j.jad.2021.12.013. [DOI] [PubMed] [Google Scholar]
  • 36.Hall JA, Liu D. Social media use, social displacement, and well-being. Curr Opin Psychol. 2022;46:101339. doi: 10.1016/j.copsyc.2022.101339. [DOI] [PubMed] [Google Scholar]
  • 37.Kraut R, Kiesler S, Boneva B, Cummings JN, Helgeson V, Crawford AM. Internet paradox revisited. J Soc Issues. 2002;58(1):49–74. doi: 10.1111/1540-4560.00248. [DOI] [Google Scholar]
  • 38.de Timary P, Luts A, Hers D, Luminet O. Absolute and relative stability of alexithymia in alcoholic inpatients undergoing alcohol withdrawal: relationship to depression and anxiety. Psychiatry Res. 2008;157(1–3):105–113. doi: 10.1016/j.psychres.2006.12.008. [DOI] [PubMed] [Google Scholar]
  • 39.Hesse C, Floyd K. Affectionate experience mediates the effects of alexithymia on mental health and interpersonal relationships. J Soc Pers Relat. 2008;25(5):793–810. doi: 10.1177/0265407508096696. [DOI] [Google Scholar]
  • 40.Preece DA, Becerra R, Robinson K, Allan A, Boyes M, Chen W, et al. What is alexithymia? Using factor analysis to establish its latent structure and relationship with fantasizing and emotional reactivity. J Pers. 2020;88(6):1162–1176. doi: 10.1111/jopy.12563. [DOI] [PubMed] [Google Scholar]
  • 41.De Berardis D, Campanella D, Gambi F, La Rovere R, Sepede G, Core L, et al. Alexithymia, fear of bodily sensations, and somatosensory amplification in young outpatients with panic disorder. Psychosomatics. 2007;48(3):239–246. doi: 10.1176/appi.psy.48.3.239. [DOI] [PubMed] [Google Scholar]
  • 42.Lee BW, Stapinski LA. Seeking safety on the internet: relationship between social anxiety and problematic internet use. J Anxiety Disord. 2012;26(1):197–205. doi: 10.1016/j.janxdis.2011.11.001. [DOI] [PubMed] [Google Scholar]
  • 43.Babadi-Akashe Z, Zamani BE, Abedini Y, Akbari H, Hedayati N. The relationship between mental health and addiction to mobile phones among university students of shahrekord. Iran Addict Health. 2014;6(3–4):93–99. [PMC free article] [PubMed] [Google Scholar]
  • 44.De Berardis D, D'Albenzio A, Gambi F, Sepede G, Valchera A, Conti CM, et al. Alexithymia and its relationships with dissociative experiences and Internet addiction in a nonclinical sample. Cycberpsychol Behav. 2009;12(1):67–69. doi: 10.1089/cpb.2008.0108. [DOI] [PubMed] [Google Scholar]
  • 45.Taylor GJ, Bagby RM, Parker JD. The alexithymia construct. A potential paradigm for psychosomatic medicine. Psychosomatics. 1991;32(2):153–164. doi: 10.1016/s0033-3182(91)72086-0. [DOI] [PubMed] [Google Scholar]
  • 46.de Timary P, Roy E, Luminet O, Fillée C, Mikolajczak M. Relationship between alexithymia, alexithymia factors and salivary cortisol in men exposed to a social stress test. Psychoneuroendocrino. 2008;33(8):1160–1164. doi: 10.1016/j.psyneuen.2008.06.005. [DOI] [PubMed] [Google Scholar]
  • 47.Nekouei ZK, Doost HT, Yousefy A, Manshaee G, Sadeghei M. The relationship of Alexithymia with anxiety-depression-stress, quality of life, and social support in coronary heart disease (A psychological model) J Educ Health Promot. 2014;3:68. doi: 10.4103/2277-9531.134816. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 48.Preece DA, Mehta A, Petrova K, Sikka P, Bjureberg J, Becerra R, et al. Alexithymia and emotion regulation. J Affect Disord. 2023;324:232–238. doi: 10.1016/j.jad.2022.12.065. [DOI] [PubMed] [Google Scholar]
  • 49.Brewer R, Cook R, Bird G. Alexithymia: a general deficit of interoception. Royal Soc Open Sci. 2016;3(10):150664. doi: 10.1098/rsos.150664. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 50.Herbert BM, Herbert C, Pollatos O. On the relationship between interoceptive awareness and alexithymia: is interoceptive awareness related to emotional awareness? J Person. 2011;79(5):1149–1175. doi: 10.1111/j.1467-6494.2011.00717.x. [DOI] [PubMed] [Google Scholar]
  • 51.Shah P, Hall R, Catmur C, Bird G. Alexithymia, not autism, is associated with impaired interoception. Cortex. 2016;81:215–220. doi: 10.1016/j.cortex.2016.03.021. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 52.Carta MG, Sancassiani F, Pippia V, Bhat KM, Sardu C, Meloni L. Alexithymia is associated with delayed treatment seeking in acute myocardial infarction. Psychother Psychosom. 2013;82(3):190–192. doi: 10.1159/000341181. [DOI] [PubMed] [Google Scholar]
  • 53.Lyvers M, Duric N, Thorberg FA. Caffeine use and alexithymia in university students. J Psychoact Drugs. 2014;46(4):340–346. doi: 10.1080/02791072.2014.942043. [DOI] [PubMed] [Google Scholar]
  • 54.Thomée S. Mobile phone use and mental health. A review of the research that takes a psychological perspective on exposure. Int J Environ Res Public Health. 2018;15(12):2692. doi: 10.3390/ijerph15122692. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 55.Thomée S, Härenstam A, Hagberg M. Mobile phone use and stress, sleep disturbances, and symptoms of depression among young adults–a prospective cohort study. BMC Public Health. 2011;11:66. doi: 10.1186/1471-2458-11-66. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 56.Zhao XF, Zhang YL, Li LF, Zhou YF, Li HZ. Reliability and validity of the Chinese version of childhoodtrauma questionnaire. Chin J Clin Rehab. 2005;20:105–107. [Google Scholar]
  • 57.Gong X, Xie XY, Xu R, Luo YJ. Psychometric properties of the Chinese versions of DASS-21 in Chinese college students. Chin J Clin Psychol. 2010;18(04):443–446. doi: 10.16128/j.cnki.1005-3611.2010.04.020. [DOI] [Google Scholar]
  • 58.Wei Q. Negative Emotions and Problematic Social NetworkSites Usage: The Mediating Role of Fear of Missing Outand the Moderating Role of Gender [Master's thesis]: Central China Normal University. 2018. [Google Scholar]
  • 59.Cerutti R, Calabrese M, Valastro C. Alexithymia and personality disorders in the adolescent non-suicidal self injury: preliminary results. Procedia Soc Behav Sci. 2014;114:372–376. doi: 10.1016/j.sbspro.2013.12.714. [DOI] [Google Scholar]
  • 60.Chung MC, Chen ZS. Gender differences in child abuse, emotional processing difficulties, alexithymia, psychological symptoms and behavioural problems among chinese adolescents. Psychiatry Q. 2020;91(2):321–332. doi: 10.1007/s11126-019-09700-w. [DOI] [PubMed] [Google Scholar]
  • 61.Kim HY. Statistical notes for clinical researchers: assessing normal distribution (2) using skewness and kurtosis. Restor Dentist Endodont. 2013;38(1):52–54. doi: 10.5395/rde.2013.38.1.52. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 62.Hayes AF. Introduction to Mediation, Moderation, and Conditional Process Analysis: A Regression-Based Approach: Introduction to Mediation, Moderation, and Conditional Process Analysis: A Regression-Based Approach. 2013. [Google Scholar]
  • 63.Podsakoff PM, Mackenzie SB, Lee JY, Podsakoff NP. Common method biases in behavioral research: a critical review of the literature and recommended remedies. J Appl psychol. 2003;88(5):879–903. doi: 10.1037/0021-9010.88.5.879. [DOI] [PubMed] [Google Scholar]
  • 64.Wan GW, Wang M, Chen ST. Child abuse in ethnic regions: evidence from 2899 girls in Southwest China. Child Youth Serv Rev. 2019;105:104457. doi: 10.1016/j.childyouth.2019.104457. [DOI] [Google Scholar]
  • 65.Shen LJ, Zhang YL, Liang W, Zhang YL. Investigation of child maltreatment: Survey among junior school pupils in Henan province of China. Asia-Pacific Psychiatry. 2015;7(1):85–90. doi: 10.1111/appy.12105. [DOI] [PubMed] [Google Scholar]
  • 66.Gao YJ, Atkinson-Sheppard S, Liu X. Prevalence and risk factors of child maltreatment among migrant families in China. Child Abuse Negl. 2017;65:171–181. doi: 10.1016/j.chiabu.2017.01.023. [DOI] [PubMed] [Google Scholar]
  • 67.Qi D, Wang YJ, Wan GW. The severity, consequences and risk factors of child abuse in China - an empirical Study of 5836 children in China's mid-western regions. Child Youth Serv Rev. 2018;95:290–299. doi: 10.1016/j.childyouth.2018.10.039. [DOI] [Google Scholar]
  • 68.Witt A, Brähler E, Fegert JM. Words don't hurt? Consequences of psychological abuse. Monatsschr Kinderh. 2021;169(7):613–621. doi: 10.1007/s00112-021-01183-z. [DOI] [Google Scholar]
  • 69.Sheikh MA. Psychological abuse, substance abuse distress, dissatisfaction with friendships, and incident psychiatric problems. J Psychosom Res. 2018;108:78–84. doi: 10.1016/j.jpsychores.2018.03.001. [DOI] [PubMed] [Google Scholar]
  • 70.Spann MN, Mayes LC, Kalmar JH, Guiney J, Womer FY, Pittman B, et al. Childhood abuse and neglect and cognitive flexibility in adolescents. Child neuropsychology. 2012;18(2):182–189. doi: 10.1080/09297049.2011.595400. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 71.Güleç MY, Altintas M, Inanç L, Bezgin ÇH, Koca EK, Guleç H. Effects of childhood trauma on somatization in major depressive disorder: the role of alexithymia. J Affect Dis. 2013;146(1):137–141. doi: 10.1016/j.jad.2012.06.033. [DOI] [PubMed] [Google Scholar]
  • 72.Paul E, Eckenrode J. Childhood psychological maltreatment subtypes and adolescent depressive symptoms. Child Abuse Negl. 2015;47:38–47. doi: 10.1016/j.chiabu.2015.05.018. [DOI] [PubMed] [Google Scholar]
  • 73.Steinberg L. We know some things: parent-adolescent relationships in retrospect and prospect. J Res Adolesc. 2001;11(1):1–19. doi: 10.1111/1532-7795.00001. [DOI] [Google Scholar]
  • 74.Karelina K, DeVries AC. Modeling social influences on human health. Psychosom Med. 2011;73(1):67–74. doi: 10.1097/PSY.0b013e3182002116. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 75.Chegeni M, Nakhaee N, Shahrbabaki PM, Shahrbabaki ME, Haghdoost A. Does childhood trauma associate with social media addiction? A cross-sectional study from Iran. Int J Ment Heal Addict. 2023;21(4):2225–2237. doi: 10.1007/s11469-021-00718-5. [DOI] [Google Scholar]
  • 76.Sheng XL, Yang M, Ge ML, Zhang L, Huang C, Cui S, et al. The relationship between internet addiction and childhood trauma in adolescents: the mediating role of social support. Front Psychol. 2022;13:996086. doi: 10.3389/fpsyg.2022.996086. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 77.Lau J, Walden DL, Wu A, Cheng KM, Lau M, Mo P. Bidirectional predictions between Internet addiction and probable depression among Chinese adolescents. J Behav Addict. 2018;7(3):633–643. doi: 10.1556/2006.7.2018.87. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 78.Hirschi T. Theory Without Ideas: reply to Akers. Criminology. 2010;34(2):249–256. doi: 10.1111/j.1745-9125.1996.tb01205.x. [DOI] [Google Scholar]
  • 79.Lam LT, Peng ZW. Effect of pathological use of the internet on adolescent mental health: a prospective study. Arch Pediatr Adolesc Med. 2010;164(10):901–906. doi: 10.1001/archpediatrics.2010.159. [DOI] [PubMed] [Google Scholar]
  • 80.Li W, Garland EL, Howard MO. Family factors in internet addiction among Chinese youth: a review of English- and Chinese-language studies. Comput Human Behav. 2014;31(feb.):393–411. doi: 10.1016/j.chb.2013.11.004. [DOI] [Google Scholar]
  • 81.Agnew R. Foundation for a general strain theory of crime and delinquency. Criminology. 1992;30(1):47–87. doi: 10.1111/j.1745-9125.1992.tb01093.x. [DOI] [Google Scholar]
  • 82.Kardefelt-Winther DA. conceptual and methodological critique of internet addiction research: towards a model of compensatory internet use. Comput Hum Behav. 2014;31:351–354. doi: 10.1016/j.chb.2013.10.059. [DOI] [Google Scholar]
  • 83.Xiao W, Zhou H, Li X, Lin X. Why are individuals with alexithymia symptoms more likely to have mobile phone addiction? the multiple mediating roles of social interaction anxiousness and boredom proneness. Psychol res Behav Manag. 2021;14:1631–1641. doi: 10.2147/PRBM.S328768. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 84.Craig AD. How do you feel–now? The anterior insula and human awareness. Nat Rev Neurosci. 2009;10(1):59–70. doi: 10.1038/nrn2555. [DOI] [PubMed] [Google Scholar]
  • 85.Craig AD. Interoception: the sense of the physiological condition of the body. Curr Opin Neurobiol. 2003;13(4):500–505. doi: 10.1016/s0959-4388(03)00090-4. [DOI] [PubMed] [Google Scholar]
  • 86.Bush G, Luu P, Posner MI. Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci. 2000;4(6):215–222. doi: 10.1016/s1364-6613(00)01483-2. [DOI] [PubMed] [Google Scholar]
  • 87.Lindquist KA, Wager TD, Kober H, Bliss-Moreau E, Barrett LF. The brain basis of emotion: a meta-analytic review. Behav Brain Sci. 2012;35(3):121–143. doi: 10.1017/S0140525X11000446. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 88.Ihme K, Dannlowski U, Lichev V, Stuhrmann A, Grotegerd D, Rosenberg N, et al. Alexithymia is related to differences in gray matter volume: a voxel-based morphometry study. Brain Res. 2013;1491:60–67. doi: 10.1016/j.brainres.2012.10.044. [DOI] [PubMed] [Google Scholar]
  • 89.Goerlich-Dobre KS, Bruce L, Martens S, Aleman A, Hooker CI. Distinct associations of insula and cingulate volume with the cognitive and affective dimensions of alexithymia. Neuropsychologia. 2014;53:284–292. doi: 10.1016/j.neuropsychologia.2013.12.006. [DOI] [PubMed] [Google Scholar]
  • 90.Moriguchi Y, Decety J, Ohnishi T, Maeda M, Mori T, Nemoto K, et al. Empathy and judging other's pain: an fMRI study of alexithymia. Cerebral cortex (New York, N.Y. 1991) 2007;17(9):2223–2234. doi: 10.1093/cercor/bhl130. [DOI] [PubMed] [Google Scholar]

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Data Availability Statement

The datasets generated and/or analysed during the current study are not publicly available due [our experimental team's policy] but are available from the corresponding author on reasonable request.


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