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. 1990 Apr 1;267(1):245–247. doi: 10.1042/bj2670245

Longer-term regulation of pyruvate dehydrogenase kinase in cultured rat cardiac myocytes.

D R Marchington 1, A L Kerbey 1, P J Randle 1
PMCID: PMC1131271  PMID: 2158309

Abstract

The increased activity of pyruvate dehydrogenase (PDH) kinase induced in hearts of rats by starvation for 48 h was maintained following preparation of cardiac myocytes, and it was also maintained, though at a decreased level, after 25 h of culture in medium 199. This loss of PDH kinase activity was not prevented by n-octanoate, dibutyryl cyclic AMP or glucagon. The PDH kinase activity of myocytes from fed rats was increased to that of starved rats after 25 h of culture with n-octanoate, dibutyryl cyclic AMP or both agents together.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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