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. 1987 May;40(5):518–523. doi: 10.1136/jcp.40.5.518

Hereditary angioedema and thyroid autoimmunity.

M F Muhlemann, K D Macrae, A M Smith, P Beck, I Hine, U Hegde, A Milford-Ward, G D Carter, P H Wise, J J Cream
PMCID: PMC1141016  PMID: 3584502

Abstract

Sera from 91 patients with hereditary angioedema were screened for thyroid antibodies. The results for the 77 patients more than 17 years old were compared with previously published data for the prevalence of thyroid disease in a large community (Whickham). Of the female patients with hereditary angioedema, the prevalence of thyroglobulin antibodies (TGA) was 14.0%, higher than the expected 3% (p less than 0.001). The prevalence of thyroid microsomal antibodies (TMA) was 20%, also higher than the expected 7.6% (p less than 0.01). The age distributions of the females in both groups differed: in the group with hereditary angioedema there was a greater proportion of younger patients which should have resulted in a lower prevalence of thyroid antibodies. Adjusting for related patients with hereditary angioedema, there was still an increased prevalence of TGA (p less than 0.01) and TMA (p less than 0.01).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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