Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1979 Apr;32(4):386–390. doi: 10.1136/jcp.32.4.386

Particle size distribution analysis for the rapid detection of microbial infection of urine.

C S Dow, A D France, M S Khan, T Johnson
PMCID: PMC1145678  PMID: 376561

Abstract

The accuracy and practicality of particle size distribution analysis for rapid screening of urine specimens are assessed. Six hundred urines were subjected simultaneously to routine bacteriological examinations and particle size distribution analysis using a Coulter Counter (ZBI) linked to a C1000 Channelyzer. There was complete agreement in the results of 593 (98.8%) specimens. Characteristic profiles of various bacterial species in infected specimens were consistently obtained. This system can easily be linked to any existing computer reporting in a district hospital laboratory, and the results of negative specimens (70--80%) can be obtained within 5--10 minutes.

Full text

PDF
390

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alexander D. N., Ederer G. M., Matsen J. M. Evaluation of an adenosine 5'-triphosphate assay as a screening method to detect significant bacteriuria. J Clin Microbiol. 1976 Jan;3(1):42–46. doi: 10.1128/jcm.3.1.42-46.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. HOEPRICH P. D. Culture of the urine. J Lab Clin Med. 1960 Dec;56:899–907. [PubMed] [Google Scholar]
  3. Johnston H. H., Mitchell C. J., Curtis G. D. An automated test for the detection of significant bacteriuria. Lancet. 1976 Aug 21;2(7982):400–402. doi: 10.1016/s0140-6736(76)92411-9. [DOI] [PubMed] [Google Scholar]
  4. KASS E. H. Asymptomatic infections of the urinary tract. Trans Assoc Am Physicians. 1956;69:56–64. [PubMed] [Google Scholar]
  5. LEIGH D. A., WILLIAMS J. D. METHOD FOR THE DETECTION OF SIGNIFICANT BACTERIURIA IN LARGE GROUPS OF PATIENTS. J Clin Pathol. 1964 Sep;17:498–503. doi: 10.1136/jcp.17.5.498. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Mackey J. P., Sandys G. H. Laboratory diagnosis of infections of the urinary tract in general practice by means of a dip-inoculum transport medium. Br Med J. 1965 Nov 27;2(5473):1286–1288. doi: 10.1136/bmj.2.5473.1286. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Smither R. Rapid screening for significant bacteriuria using a Coulter Counter. J Clin Pathol. 1977 Dec;30(12):1158–1162. doi: 10.1136/jcp.30.12.1158. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES