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. 1979 Jun;32(6):538–541. doi: 10.1136/jcp.32.6.538

Haemophilus influenzae type b antigenuria in children.

J Kaldor, R Asznowicz, B Dwyer
PMCID: PMC1145734  PMID: 313940

Abstract

Detection of Haemophilus influenzae type b (HIb) antigenuria by latex agglutination has been shown to be sensitive, specific, and rapid. In children, antigenuria persisted for a mean duration of 10 days and a maximum of 18 days. Antigenuria was demonstrated in 25 of 30 patients with HIb infection but not in 62 with other types of infection. In five children, antigenuria confirmed the diagnosis in the absence of bacteriological confirmation. In five other children, antigenuria was not found, but in this group the antigen was detected in another body fluid or HIb was recovered.

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Selected References

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  1. Converse G. M., Gwaltney J. M., Jr, Strassburg D. A., Hendley J. O. Alteration of cerebrospinal fluid findings by partial treatment of bacterial meningitis. J Pediatr. 1973 Aug;83(2):220–225. doi: 10.1016/s0022-3476(73)80479-2. [DOI] [PubMed] [Google Scholar]
  2. Coonrod J. D. CIE detection of bacterial antigens in meningitis. J Pediatr. 1977 Apr;90(4):676–677. doi: 10.1016/s0022-3476(77)80425-3. [DOI] [PubMed] [Google Scholar]
  3. Feigin R. D., Wong M., Shackelford P. G., Stechenberg B. W., Dunkle L. M., Kaplan S. Countercurrent immunoelectrophoresis of urine as well as of CSF and blood for diagnosis of bacterial meningitis. J Pediatr. 1976 Nov;89(5):773–775. doi: 10.1016/s0022-3476(76)80802-5. [DOI] [PubMed] [Google Scholar]
  4. Ingram D. L., Anderson P., Smith D. H. Countercurrent immunoelectrophoresis in the diagnosis of systemic diseases caused by Hemophilus infleunzae type b. J Pediatr. 1972 Dec;81(6):1156–1159. doi: 10.1016/s0022-3476(72)80252-x. [DOI] [PubMed] [Google Scholar]
  5. Kaldor J., Asznowicz R., Buist D. G. Latex agglutination in diagnosis of bacterial infections, with special reference to patients with meningitis and septicemia. Am J Clin Pathol. 1977 Aug;68(2):284–289. doi: 10.1093/ajcp/68.2.284. [DOI] [PubMed] [Google Scholar]
  6. Lewin E. B. Partially treated meningitis. Am J Dis Child. 1974 Aug;128(2):145–147. doi: 10.1001/archpedi.1974.02110270019005. [DOI] [PubMed] [Google Scholar]
  7. Mandal B. K. The dilemma of partially treated bacterial meningitis. Scand J Infect Dis. 1976;8(3):185–188. doi: 10.3109/inf.1976.8.issue-3.12. [DOI] [PubMed] [Google Scholar]
  8. McCracken G. H., Jr Rapid identification of specific etiology in meningitis. J Pediatr. 1976 Apr;88(4 Pt 1):706–708. doi: 10.1016/s0022-3476(76)80067-4. [DOI] [PubMed] [Google Scholar]
  9. Newman R. B., Stevens R. W., Gaafar H. A. Latex agglutination test for the diagnosis of Haemophilus influenzae meningitis. J Lab Clin Med. 1970 Jul;76(1):107–113. [PubMed] [Google Scholar]
  10. Shackelford P. G., Campbell J., Feigin R. D. Countercurrent immunoelectrophoresis in the evaluation of childhood infections. J Pediatr. 1974 Oct;85(4):478–481. doi: 10.1016/s0022-3476(74)80448-8. [DOI] [PubMed] [Google Scholar]
  11. Suksanong M., Dajani A. S. Detection of Haemophilus influenzae type b antigens in body fluids, using specific antibody-coated staphylococci. J Clin Microbiol. 1977 Jan;5(1):81–85. doi: 10.1128/jcm.5.1.81-85.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Whittle H. C., Tugwell P., Egler L. J., Greenwood B. M. Rapid bacteriological diagnosis of pyogenic meningitis by latex agglutination. Lancet. 1974 Sep 14;2(7881):619–621. doi: 10.1016/s0140-6736(74)91943-6. [DOI] [PubMed] [Google Scholar]

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