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. 2024 Oct 17;4(10):e0002635. doi: 10.1371/journal.pgph.0002635

Assessments of effectiveness of technologies utilizations in VIHSCM among selected health facilities in Tanzania mainland

Henry A Mollel 1,*, Lawrencia D Mushi 1, Richard V Nkwera 2
Editor: Anat Rosenthal3
PMCID: PMC11486421  PMID: 39418255

Abstract

Immunization coverage remains a challenge in many developing countries Tanzania being no exception. The current increase in technology adoption in the immunisation supply chain promises the attainment of universal health coverage and Sustainable Development Goals (SDGs) on immunisation. This study evaluates the effectiveness of technology integration in Vaccine and Immunization Health Supply Chain Management (VIHSCM) in Tanzania. This study adopted an exploratory descriptive cross-sectional design. The study collected data using structured questionnaires from health facilities that adopted VIHSCM technologies in Arusha, Mwanza, Morogoro and Mbeya regions, Tanzania. Data were analysed using descriptive statistics and cross-tabulations with the aid of the Statistical Package of Social Sciences 23rd Edition (SPSS). The study included 37 health facilities in Tanzania, mainly district hospitals (59.5%). Respondents were mostly female (70.3%), averaging 45 years old, with 1–5 years of immunization experience. While all facilities had refrigerators, digital reporting tool usage was low, with many relying on paper forms. District hospitals and health centres had higher digital tool adoption rates compared to dispensaries. Despite the underutilization of systems like ILS, TImR, and GoTHOMIS, digital tools were deemed crucial for vaccine supply management. While District Hospitals report high relevance of digital tools, Health Centres and Dispensaries show moderate relevance. Challenges include incomplete technology adoption, inadequate infrastructure, and variable perceptions of technology effectiveness. Digital technologies significantly improve vaccine and immunization supply chain management, particularly in larger facilities. Technologies like the Tanzania Immunization Registry (TImR) and Integrated Logistics Systems (ILS) enhance data accuracy and efficiency. Addressing facility-specific challenges and increasing investment in digital tools are crucial for optimizing vaccine supply chains and achieving immunization targets in Tanzania. Future research should involve larger samples to generalize findings and further explore technology impacts on VIHSCM.

1. Introduction

Immunization Supply Chain and Logistics is crucial for the Immunization Agenda 2030 (IA2030), which outlines a global strategy for vaccines and immunisation for 2021–2030 [1]. IA2030 emphasises integrating immunisation into primary health care to achieve universal health coverage and the health-related Sustainable Development Goals (SDGs) [2]. Despite the historical success of routine immunization programs, national vaccine supply chains continue to encounter persistent challenges due to the introduction of new vaccines, the need for adaptation to evolving delivery strategies, and the growing demand for advanced cold chain technologies [3, 4]. Consequently, sustained investment and continuous innovation in the Immunization Supply Chain and Logistics (ISCL) are essential to sustaining and amplifying the impact of vaccination programs [5, 6]. National immunisation programs are transforming supply chains by integrating new technologies and innovative methods for Effective Vaccine Management (EVM) to keep pace with the changing landscape of immunisation programmes [4, 79]. The WHO-UNICEF assessment highlights the crucial role of modern technologies in strengthening vaccine supply chains [2, 10]. Effective technology utilization, including advanced inventory tracking and cold chain management, is vital for optimizing vaccine distribution and improving coverage, especially in low- and middle-income countries [1113].

Despite being recognized as one of Africa’s best-performing immunisation programs, Tanzania prioritises improving its national immunization efforts [12, 14]. The Ministry of Health and Social Welfare (MoHSW) developed the National Immunization Strategy (NIS) for 2021–2025, aligning with the Health Sector Strategic Plan V, Immunisation Agenda 2030, and Gavi 5.0 [15]. The NIS aims to deliver lifelong protection through high-quality, equitable immunization services and to integrate a resilient program into primary healthcare [14, 15]. To support this, the MoHSW’s Immunization and Vaccines Development (IVD) department implemented advanced technologies, including the Vaccine Information Management System (VIMS), Warehouse Management Information Systems, and the Tanzania Immunization Registry (TImR), to enhance supply chain and logistics [11, 12, 16].

However, despite these efforts, some regions in Tanzania still report immunisation coverage below 80%, reflecting disparities across the country [17]. Tanzania DHS reported a decline in full vaccination rates for basic antigens from 73% in 1991–2016 to 53% in 2022, while the percentage of unvaccinated children aged 12–23 months fluctuated between 2% and 5% [18]. The decline in fully vaccinated children since 2015–16 is mainly due to limited capacity, inaccurate target populations, poor vaccine supply visibility, and challenges in tracking immunisation defaulters worsened by the COVID-19 outbreak, [4, 7, 8, 18]. The Tanzania National Immunization Strategy (2021–2025) identified critical challenges, such as inadequate monitoring devices, incomplete temperature charts, and insufficient responses to alarms (MOH, 2020; UNICEF, 2020). Similarly, Both the 2015 Effective Vaccine Management Assessment and a recent study of 57 GAVI-eligible countries reveal a global decline in vaccine handling, with less than 25% meeting maintenance and stock standards and only 29% ensuring proper temperature control [4, 19]. Additionally, challenges such as inadequate electricity, unreliable network connectivity, limited information on cold chain equipment availability, and a lack of trained health personnel have been acknowledged as obstacles in integrating technologies for vaccine management in health facilities [7, 9, 2022]. Addressing these challenges and evaluating the efficacy of current technologies in vaccine supply chains remains a critical area of inquiry, and this study significantly contributes to the existing literature by assessing the effectiveness of technology utilization in Vaccine and Immunization Health Supply Chain Management (VIHSCM) at primary facilities in Tanzania.

2. Design and method

2.1. Study setting

A facility-based exploratory descriptive cross-sectional design approach was employed to understand the effectiveness of utilization of technologies for VIHSCM across health facilities in three purposively selected regions of mainland Tanzania namely Arusha, Mwanza, Morogoro and Mbeya. This research design allowed both qualitative and quantitative data to be collected simultaneously using a structured questionnaire, analysed, and later combined for interpretation to provide a comprehensive analysis of the effectiveness of the utilization of technologies for VIHSCM across health facilities.

2.2. Data collection instruments and sampling procedures

Data collection was conducted in three purposively selected regions of mainland Tanzania namely Arusha, Mwanza, Morogoro and Mbeya. In each of the selected regions, two districts were purposively selected. The criteria for selection of both regions and districts were the urban-rural divide and the rate of vaccines and immunization uptake rate. The selection was based on capturing contextual variations that can influence the uptake, scale and integration of adopted technologies and innovations into existing systems and policies.

In the selected regions and councils, two and three relevant officials were selected purposively based on involvement in the implementation of vaccines and immunization activities. These included the Regional Medical Officer, Regional Immunization and Vaccine Officer, District Medical Officer, District Immunization and Vaccine Officer, and District HMIS (MTUHA) Focal Person. In each of the selected health facilities, three staff were purposively selected based on their involvement in vaccine and immunization management. These were the health facility in-charge, the in-charge of Reproductive and Child Health (RCH), and the RCH vaccine coordinator.

2.3. Data collection

Primary data were collected using a Structured questionnaire and Secondary data were collected through documentary review. A structured Questionnaire was administered to 37 respondents at the health facility level.

2.4. Data processing and analysis

Data collected during the study was cleaned, processed and analysed using IBM Statistical Package for Social Studies (SPSS). Because of the small number of records, the analysis only focused on descriptive statistics (frequencies, percentages, means, and standard deviation). It was performed for all demographic and health facilities characteristics as well as for study variables including health worker’s understanding of the presence and utilization of technologies for VISHSCM.

2.5. Ethical considerations

Ethical clearance was obtained from the National Institute for Medical Research. The research was also approved by Mzumbe University. Permission to conduct research in the relevant institutions was obtained from the Ministry of Health (MOH) and the President’s Office of Regional Administration and Local Government (PORALG). Participants were given a consent form describing the purpose of the study and their position to participate or terminate their participation even during the interview. Only consented participants were interviewed.

3. Results

3.1. Health facility and respondents’ characteristics

The findings show that 37 respondents from enrolled health facilities gave complete responses making a response rate of 100 percent. The study assessed health facilities in four regions Arusha, Morogoro, Mbeya, and Mwanza regions. A total of 37 respondents from health facilities, in 8 districts of 4 regions participated in this study. The majority of participants were from district hospitals, accounting for 59.5% of the study population. Health centres and dispensaries accounted for smaller proportions, with 10.8% and 29.7%, respectively. The study shows that 11 (29.7%) respondents were male while 26 (70.3%) of the respondent were female. The age distribution of the respondents across health facilities showed that the average age was 45 years old. About 29.7 were RCH in charge coordinators with facility RCH in charge 24.3%, medical officer in charge, MTUHA, Medical Facility In charge, Facility In charge nurse, and Facility In charge. The results show that 17 (45.9%) had been working on Vaccines and Immunization activities for about 5 years, 6–10 years of Experience (27%), while (16.2%) had more than 10 years of experience and (10.8%) had less than year Experience in Vaccines and Immunization Management. (Table 1).

Table 1. Demographic and Institutional characteristics across the health facility level.

Variable Frequency(n) Percentage(%)
Sex    
    Male 11 29.7
    Female 26 70.3
    Total 37 100
Age    
    25–34 12 32.4
    35–44 12 32.4
    45–54 10 27
    55–64 3 8.1
    Total 37 100
Facility Level    
    District Hospital 22 59.5
    Health Center 4 10.8
    Dispensary 11 29.7
Job Title    
RCH in charge Coordinator 11 29.7
Medical officer In charge 8 21.6
MTUHA 5 13.5
Facility incharge 2 5.4
Facility RCH In charge 9 24.3
Medical Facility Incharge 1 2.7
Facility In charge Nurse 1 2.7
Duration(Years)    
< 1 4 10.8
1–5 17 45.9
6–10 10 27
>11 6 16.2
Total 37 100

The data on duration of employment indicates that the largest proportion of individuals (45.9%) have been employed for 1–5 years, suggesting a turnover rate that may be common in healthcare settings. Approximately 27.0% have been employed for 6–10 years, indicating a notable presence of individuals with moderate tenure. A smaller proportion of individuals (16.2%) have been employed for over 11 years, indicating longevity in their positions. Only 10.8% of individuals have been employed for less than 1 year, suggesting a relatively smaller proportion of newcomers to their roles. (Table 1)

3.2. Status of technology utilizations for VIHSCM across health facilities

The Data shows that in all 37 visited health facilities six visited district councils reported the presence of refrigerators (Table 2).

Table 2. Technology used for vaccines and immunization storage.

Technologies District Hospital Health Centre Dispensary Total
Refrigerator 22(59.5%) 4(10.8%) 11(29.7%) 37 (100%)

About 13.6% and 25% of respondents reported the predominantly use of software for reporting with District Hospitals and Health Centres respectively indicating a relatively low adoption rate compared to other methods at the District Hospital (Table 3). About (25%) to (72.7%) of respondents in health centres and Dispensaries respectively reported that the majority of reporting in all facility types is done using forms. while No software was used for reporting in Dispensaries. A significant portion of facilities, particularly District Hospitals, employ both software and forms for reporting reflecting efforts to leverage the benefits of both digital and paper-based reporting systems to ensure comprehensive data capture (Table 3).

Table 3. Tools used to report the used vaccines.

District Hospital Health Centre Dispensary Total
Software 3 (13.6%) 1 (25%) 0 4 (10.8%)
Form 9 (40.9%) 1 (25%) 8(72.7%) 18 (48.6%)
Both software and form 10 (45.5%) 2 (50%) 3 (27.3%) 15 (40.5%)
Total 22 (100%) 4(100%) 11(100%) 37(100%)

3.3. Tools for vaccines and immunization management

About (9.1%) of respondents reported that District Hospitals employ electronic software for vaccine administration. While (25%) of respondents reported the usage of electronic software in Health Centres, indicating a greater uptake of digital tools at this level. About (18.2%) of respondents reported that similar to District Hospitals, Dispensaries also exhibit a lower adoption rate of electronic software for vaccine administration (Table 4).

Table 4. Tool used to administer vaccine (B10).

 Technology District Hospital Health Centre Dispensary Total
Electronic software 2(9.1%) 1(25%) 2(18.2) 5(13.5)
Form 10(45.5%) 2(50%) 6(54.4%) 18(48.6%)
Both electronic software and form 10(45.5%) 1(25%) 3(27.3%) 14(37.8%)
  37(100)

A majority (45.5%) of respondents reported that District Hospitals rely on traditional paper-based forms for administering vaccines. A similar trend is observed, with (50%) of respondents reporting that Health Centres utilise paper forms as the primary tool for vaccine administration. While (54.4%) of respondents reported that Dispensaries exhibit the highest reliance on paper-based forms for vaccine administration among the facility types (Table 4).

In managing supplies and logistics of vaccines and immunization services at the health facility about (25%) of the respondents reported that Integrated Logistics Systems (ILS) are Utilized by Health Centres, about (4.5%) and (27.3%) of the respondents reported that the Tanzania Immunization Registry (TImR) is primarily used in District Hospitals and Dispensaries respectively. About (4.5%) and (18.2%) of respondents reported DHIS 2 is used in District Hospitals and Dispensaries, respectively. About (18.2%) and (9.1%) of reported GoTHOMIS are used in District Hospitals and Dispensaries. The Data show that respondents reported a significant proportion of facilities, especially Health Centres (75%) and Dispensaries (45.5%), do not use any software for logistics management (Table 5).

Table 5. VIHSCM tool for supplies & logistics management (B10).

 Technology District Hospital Health Centre Dispensary Total
Integrated Logistics Systems (ILS) 0 1 (25%) 0 1 (2.7%)
Tanzania Immunization Registry (TImR) 10(45.5%) 0 3(27.3%) 13 (35.1%)
DHIS 2 1(4.5%) 0 2(18.2%) 3(8.1%)
GoTHOMIS 4(18.2) 0 1(9.1%) 5(13.5%)
No software 7(7) 3(75%) 5(45.5%) 15(40.5%)
  37(100)

3.4. Relevancy and effectiveness of technology utilizations in VIHSC management

The Data show that a significant majority of respondents (62.2%) consider the tools and software to be very relevant in facilitating the timely supply of vaccines in District Hospitals. While a notable portion of respondents (37.8%) mainly in Health centres and Dispensary perceives the tools as moderately relevant (Table 6).

Table 6. Relevancy of the tool or software in facilitating timely supply of vaccines (13).

District Hospital Health Centre Dispensary  Total
Very Relevant 16 (72.0%) 2 (50%) 5 (45.5%) 23(62.2%)
Moderate relevant 6 (27.3%) 2 (50%) 6 (54.5%) 14(37.8)
Total 22 (100%) 4 (100%) 11(100%) 37(100%)

The Data in Table show that about (18.2%) and (27.3%) of respondents reported technology has contributed to effective management in a significant portion mainly districts, Hospitals, and Dispensaries respectively. A considerable number of respondents (36.4%), (50%), and (36.4%) reported increased access to vaccines as a result of technological integration in District Hospitals, Health Centres and Dispensaries. While (50%) of respondents reported the highest increase in vaccine availability in Health Centres. Only a small number of respondents (9.1%) reported improved monitoring of vaccine ordering in Dispensaries. About (9.1%) of respondents have reported benefits in maintaining vaccine quality in District Hospitals. About (18.2%) of respondents reported benefits in monitoring vaccine temperature in Dispensaries. About (9.1%) of Respondents reported that Technology has facilitated Direct Communication Between Facility and DIVO in the District hospitals (Table 7).

Table 7. The way technology has assisted in increasing access and utilization of vaccines and immunization (B6).

District Hospital Health Centre Dispensary  Total
Effective management 4(18.2%) 0 3(27.3) 7 (18.9)
Increased access of vaccines at the facility 8(36.4%) 2(50%) 4(36.4%) 14 (37.8%)
Increased availability of vaccines at the facility 6(27.3%) 2(50%) 1(9.1%) 9(24.3)
Increased monitoring of vaccine ordering N/R 0 1(9.1%) 1(2.7%)
Maintain the quality of the vaccine 2(9.1%) 0 N/R 2(5.4%)
Monitoring of temperature N/R 0 2 (18.2%) 2(5.4%)
Provide direct communication between the facility and DIVO 2 (9.1%) 0 0 2(5.4%)
Total 37(100%)

3.5. Tendencies of vaccines stock out and ordering across health facilities levels

The Data show that about (40.9%) of District Hospitals experience stock-outs for specified vaccines once a year, while the majority (59.1%) never experience stock-outs. About Half of the Health Centres (50%) report experiencing stock-outs once a year and the other half (50%) never experience stock-outs. The majority of Dispensaries (63.6%) report experiencing stock-outs for specified vaccines once a year, while a smaller proportion (36.4%) never experience stock-outs. The Data also show that Across all facility types, the duration from ordering to delivery of vaccines takes only a few days (Table 8).

Table 8. Tendencies of vaccines stock out and ordering across health facilities levels.

District Hospital Health Centre Dispensary Total
How often do you get out of stock for the specified vaccines? Once a year 9(40.9) 2 (50) 7(63.6) 18(48.6)
Never experienced stock-out 13(59.1) 2 (50) 4(36.4) 19(51.4)
How long does it take from ordering to delivery? Takes only few days 22 (100) 4(100) 11(100) 37(100)

4. Discussion

This study highlighted the effectiveness of technology in children’s vaccine and immunization supply chain management. The study findings indicate that health workers are employing technologies for the storage and reporting of vaccines in health facilities. Literature supports that electronic systems optimize the reporting process, conserve time and resources, and enhance the tracking of vaccine inventories, scheduling, and monitoring, thereby improving overall vaccine management [21, 23].

The findings indicate that technology integration in health facilities is incomplete. Specifically, the Integrated Logistic System (ILS) is not employed in dispensaries and health centres. The Tanzania Immunization Registry (TImR), while operational in some areas, is only partially implemented across 3,736 facilities in 15 regions. TImR is functional in Arusha and Mwanza but is not utilized in Mbeya, with its implementation halted in Meru and Longido due to equipment malfunctions [7]. The Government of Tanzania Health Management Information System (GoTHOMIS) is exclusively employed at the District Council hospital level, with limited application in Health Centres or Dispensaries. This is consistent with findings from studies conducted in Tanzania, South Africa, and India, which reveal that health facilities transitioning from paper-based systems to digital platforms for vaccine ordering, administration, and reporting encounter significant challenges. These challenges include inadequate internet connectivity, frequent power outages, and inconsistencies between reported vaccine stocks and physical inventory counts [7, 9, 21, 23]. These issues highlight the need for clear national policies to guide the digital transition. Despite these challenges, the Tanzanian government remains committed to fully implementing digital health systems by the end of 2021 to improve efficiency, data quality, and system reliability in immunization services.

The findings indicate that digital tools and software are broadly recognized as crucial for the timely delivery of vaccines, particularly in larger facilities like District Hospitals (Table 6). Conversely, some Health Centres and Dispensaries view these technologies as having only moderate relevance, suggesting that there are opportunities for enhancing their effectiveness and integration [7, 24]. The success of digital tools in vaccine supply chains shows how important they are for strengthening immunization efforts. This highlights the need for ongoing investment and improvements in these systems. Additionally, addressing the specific challenges of different healthcare facilities is crucial for improving vaccine logistics and immunization outcomes in Tanzania, as noted by [7, 23, 25] and [24]

The findings presented in Table 6 indicate that technology substantially enhances vaccine access and utilization by improving management practices, increasing availability, ensuring quality, and enabling better communication. However, the adoption and impact of specific technological interventions differ among facility types. District Hospitals and Health Centres experience more significant benefits in terms of improved access and availability, whereas Dispensaries gain advantages in effective management and temperature monitoring. Research suggests that the digital transformation of immunization logistics has markedly strengthened immunization programs by streamlining health workers’ tasks, enhancing data quality and utilization, minimizing stock-outs, and boosting coverage. By 2021, electronic immunization registries (EIR) had been piloted or implemented in over 50 low- and middle-income countries [4, 7, 9, 24].

The findings highlight that digital tools and software are largely viewed positively for ensuring a reliable vaccine supply across healthcare facilities in Tanzania. District Hospitals generally find these tools effective, while Health Centres and Dispensaries show more varied opinions. Addressing these differences and making continuous improvements to the tools are crucial for optimizing vaccine supply chain management and improving immunization outcomes. The findings in Table 7 reveal that, although most healthcare facilities encounter occasional vaccine stock-outs, the rapid delivery turnaround times demonstrate effective supply chain management. This underscores the critical need to address stock-out issues and ensure timely delivery to sustain high immunization coverage and meet public health objectives. This observation aligns with previous research, which highlights the importance of these factors in achieving effective immunization programs [7, 8, 20, 21, 23].

5. Conclusion

This study highlights the effectiveness of digital technologies in improving children’s vaccine and immunization supply chain management in Tanzania. The transition from paper-based to digital systems has significantly enhanced data accuracy, efficiency, and vaccine management, despite ongoing challenges such as poor internet connectivity, battery issues, and mismatched vaccine stocks. Technologies like the Tanzania Immunization Registry (TImR), Integrated Logistic System (ILS) and the Government of Tanzania Health Management Information System (GoTHOMIS) have been implemented in various facilities, though nationwide adoption is still incomplete.

VIHSCM have proven highly relevant in larger facilities like District Hospitals, though their relevance in Health Centres and Dispensaries indicates areas for improvement. Addressing these challenges can further optimise vaccine supply chains and improve immunization outcomes. The government’s commitment to nationwide digital health implementation aims to enhance efficiency, improve data quality, reduce workload, and ensure continuous system usage. Overall, the study underscores the need for continuous investment in and enhancement of digital tools to improve vaccine supply chain management and immunization outcomes in Tanzania. Addressing the specific challenges faced by different facility types will further optimize the integration of immunization programs into primary healthcare systems, thereby contributing to the achievement of universal health coverage (UHC) and the fulfilment of health-related Sustainable Development Goals (SDGs).

6. Research limitations

Data collections were conducted in three regions and six councils; therefore, our findings, conclusion and recommendations reflect the settings and technologies applied in those councils. Using a small sample size might make it difficult to draw conclusions and generalize. However, the findings can be replicated in other contexts since the context in which Vaccination and Immunization of VIHSCM processes do not vary significantly and are guided by similar operational frameworks. Despite these limitations, the study’s direct observation study design can show an actual practice. vaccine and cold chain management practices. Future research needs to be conducted with a larger sample of health facilities and health workers in the country to be able to realise and generalise the effectiveness of technology utilisation technologies for VIHSCM.

Acknowledgments

The authors thank the top leadership of Mzumbe University for their technical support and for facilitating collaboration with the University of Rwanda and the implementation of this study. We are also thankful to Noel Otieno, Irene Moshi and Rehema Mgoda for their support as research assistance. Last but not least, we thank everyone who participated and contributed to this study.

Data Availability

Data are available for open access via the Inter-university Consortium for Political and Social Research (ICPSR), openICPSR, at the following link: https://doi.org/10.3886/E209303V1.

Funding Statement

The authors declare that this work was funded by the University of Rwanda, East African Regional Centre of Excellence for Vaccines, Immunisation, and Health Supply Chain Management (UR EAC RCE-VIHSCM), Research Grant Number RCE-VIHSCM 002/2021, through the Research Grant Scheme to All Authors (HM; RM & RM). However, the funder had no direct involvement in the study design, data collection and analysis or writing of this manuscript.

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PLOS Glob Public Health. doi: 10.1371/journal.pgph.0002635.r001

Decision Letter 0

Anat Rosenthal

2 Apr 2024

PGPH-D-23-02110

Assessments of Effectiveness of Technologies Utilizations in VIHSCM Among Selected Health Facilities in Tanzania Mainland

PLOS Global Public Health

Dear Dr. Mollel,

Thank you for submitting your manuscript to PLOS Global Public Health. After careful consideration, we feel that it has merit but does not fully meet PLOS Global Public Health’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

In your revisions please address the reviewers comments as well as the following:

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2. Please provide more background on the Tanzanian context in general, and more information on the supply chain management system in particular.

3. The article would benefit from more focus on the policy implications of the study in Tanzania and beyond.  

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Comments to the Author

1. Does this manuscript meet PLOS Global Public Health’s publication criteria? Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe methodologically and ethically rigorous research with conclusions that are appropriately drawn based on the data presented.

Reviewer #1: Yes

Reviewer #2: Yes

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2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: I don't know

Reviewer #2: No

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3. Have the authors made all data underlying the findings in their manuscript fully available (please refer to the Data Availability Statement at the start of the manuscript PDF file)?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception. The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: Yes

Reviewer #2: No

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4. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS Global Public Health does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: Yes

Reviewer #2: No

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5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: This paper deals with an important topic with applied implications. I have indicated that this manuscript as it stands, needs a major revision. The reasons for my recommendation are two-fold: 1. There are multiple stylistic and grammatical errors and inconsistencies which undermine the findings being documented. I have highlighted in yellow some of these grammatical inconsistencies in the attached file. As a first step, someone needs to go through the entire manuscript and do a thorough check of the writing style and grammar. 2. The authors have presented a textual representation of the numbers that are already presented in tables; in other words, this is duplication of information, which readers might find unnecessary. I strongly suggest that rather repeating the numbers in a paragraph that are already in a table, the authors should focus more on analyzing the data and the implications of their findings. The findings of this study are interesting, but the conclusions are rather bland in that the authors need to say a lot more about what these data mean for Tanzania's policy and logistics concerned with making its vaccination program highly effective. I would be happy to review a revised version of this manuscript.

Reviewer #2: This is a helpful study relevant to policymakers in Tanzania, and I’m so glad that health workers found the supply chain management system useful.

As the manuscript is written, it does not really articulate what this research is adding to the literature or knowledge on this topic that would be useful or relevant to researchers working on immunization more broadly. This could help elevate this paper to broaden its interest to those beyond Tanzania.

The manuscript could benefit from a more targeted articulation of what information this adds to the literature and what the broad take-aways are. Some suggestions to this end:

• The introduction would be strengthened by clearly articulating the gap in academic knowledge that this article is filling. The practical utility of this information is clear—but what is this paper adding to the academic literature? What are the gaps in literature in supply chain management broadly, beyond Tanzania (and perhaps even beyond immunization)?

• The manuscript would benefit from some information on the supply chain management system itself; since it seems to be useful, readers from other countries will want that detail.

• I was interested in some more detailed analysis that could help policymakers in Tanzania and elsewhere. Did satisfaction with the system differ, for example, depending on whether the system was electronic or on paper?

• The tables are somewhat confusing as laid out; I was not always sure what the percentages were referring to. For example in Table 2 I initially thought that not all facilities had refrigerators; I think reformatting the tables could help with this.

• Qualitative interviews were mentioned but not included in the manuscript. What insights come from that material?

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6. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

Do you want your identity to be public for this peer review? If you choose “no”, your identity will remain anonymous but your review may still be made public.

For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #1: No

Reviewer #2: No

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[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

Attachment

Submitted filename: PGPH-D-23-02110.pdf

pgph.0002635.s001.pdf (557.8KB, pdf)
PLOS Glob Public Health. doi: 10.1371/journal.pgph.0002635.r003

Decision Letter 1

Anat Rosenthal

22 Jul 2024

PGPH-D-23-02110R1

Assessments of Effectiveness of Technologies Utilizations in VIHSCM Among Selected Health Facilities in Tanzania Mainland

PLOS Global Public Health

Dear Dr. Mollel,

Thank you for submitting your manuscript to PLOS Global Public Health. After careful consideration, we feel that it has merit but does not fully meet PLOS Global Public Health’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

While the article has undergone major revisions with much success, a few points still require authors' attention. In your revisions, please address reviewer's 2 comments regarding the need to better articulate this article's contribution to the literature on vaccine management systems. In addition, please refer to the comments on the presentation of data (tables 2 and 4) as well as the need for clarifications regarding the use of interviews in the process of data collection and the notes about formatting, and make the appropriate changes.

Please submit your revised manuscript by Aug 21 2024 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at globalpubhealth@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pgph/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:

  • A rebuttal letter that responds to each point raised by the editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

We look forward to receiving your revised manuscript.

Kind regards,

Anat Rosenthal

Academic Editor

PLOS Global Public Health

Journal Requirements:

1. Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice.

Additional Editor Comments (if provided):

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. If the authors have adequately addressed your comments raised in a previous round of review and you feel that this manuscript is now acceptable for publication, you may indicate that here to bypass the “Comments to the Author” section, enter your conflict of interest statement in the “Confidential to Editor” section, and submit your "Accept" recommendation.

Reviewer #1: All comments have been addressed

Reviewer #2: (No Response)

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2. Does this manuscript meet PLOS Global Public Health’s publication criteria? Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe methodologically and ethically rigorous research with conclusions that are appropriately drawn based on the data presented.

Reviewer #1: Yes

Reviewer #2: Partly

**********

3. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: I don't know

Reviewer #2: No

**********

4. Have the authors made all data underlying the findings in their manuscript fully available (please refer to the Data Availability Statement at the start of the manuscript PDF file)?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception. The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: Yes

Reviewer #2: Yes

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS Global Public Health does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: Yes

Reviewer #2: No

**********

6. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: The abstract (content and style) on the cover page is different from the Abstract included in the manuscript. Please reconcile.

Reviewer #2: The writing and tables in this article have been improved, but this paper still needs major work before it is ready for publication. Really articulating what this paper is adding to the existing literature will be very helpful in showing what this important work is adding.

--This paper would benefit from more information in the introduction in terms of what this study adds specifically to the literature on vaccine management systems. Then, this should be clearly articulated in the conclusion.

--If interview data are used in the authors' thinking, that is wonderful. If so, that interview data should be presented in the results, not discussion. They should be integrated in the discussion with quotes, for example in 3.4. If they are not used in the paper, that should be noted in the methods.

--The paper needs major attention to formatting and proofreading. For example, an abstract seems to be have been inserted into the methods on p. 6. A careful proofread of the entire document is needed. There are many grammatical errors and some references are not formatted correctly.

--p. 4, interesting information on the sharp decrease in immunization coverage in 2022. Can this be drawn out a bit more, as the issues listed did not really seem to explain it (wouldn’t these have been issues before)? Is this about COVID, or some political dynamics? How is this related (or not related) to the topic of this paper?

--The formatting of Table 2 still appears incorrect. The percentages seem to be wrong across the columns. How can less than half of all facilities have refrigerators, but then it somehow adds up to 100%?

--Throughout the results, rather than repeating what is in the tables, I suggest using the narrative to hit on and discuss the key points, perhaps with additional inforamtion from the interviews. Much of the discussion could be shortened (eg., it’s fine to just state that refrigerators are everywhere and then move on).

--The formatting of Table 4 is still very confusing; can this be reformatted for clarity?

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7. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

Do you want your identity to be public for this peer review? If you choose “no”, your identity will remain anonymous but your review may still be made public.

For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #1: No

Reviewer #2: No

**********

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

PLOS Glob Public Health. doi: 10.1371/journal.pgph.0002635.r005

Decision Letter 2

Anat Rosenthal

26 Aug 2024

Assessments of Effectiveness of Technologies Utilizations in VIHSCM Among Selected Health Facilities in Tanzania Mainland

PGPH-D-23-02110R2

Dear Professor Mollel,

We are pleased to inform you that your manuscript 'Assessments of Effectiveness of Technologies Utilizations in VIHSCM Among Selected Health Facilities in Tanzania Mainland' has been provisionally accepted for publication in PLOS Global Public Health.

Before your manuscript can be formally accepted you will need to complete some formatting changes, which you will receive in a follow up email. A member of our team will be in touch with a set of requests.

Please note that your manuscript will not be scheduled for publication until you have made the required changes, so a swift response is appreciated.

IMPORTANT: The editorial review process is now complete. PLOS will only permit corrections to spelling, formatting or significant scientific errors from this point onwards. Requests for major changes, or any which affect the scientific understanding of your work, will cause delays to the publication date of your manuscript.

If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they'll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact globalpubhealth@plos.org.

Thank you again for supporting Open Access publishing; we are looking forward to publishing your work in PLOS Global Public Health.

Best regards,

Anat Rosenthal

Academic Editor

PLOS Global Public Health

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Reviewer Comments (if any, and for reference):

Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    Attachment

    Submitted filename: PGPH-D-23-02110.pdf

    pgph.0002635.s001.pdf (557.8KB, pdf)
    Attachment

    Submitted filename: Response to Reviewers_Rebattles.pdf

    pgph.0002635.s002.pdf (153.5KB, pdf)
    Attachment

    Submitted filename: Rebattle Letter_Response to Reviewers.docx

    pgph.0002635.s003.docx (21.3KB, docx)

    Data Availability Statement

    Data are available for open access via the Inter-university Consortium for Political and Social Research (ICPSR), openICPSR, at the following link: https://doi.org/10.3886/E209303V1.


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