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. 1988 Feb 1;249(3):877–881. doi: 10.1042/bj2490877

Phosphatidylinositol 4,5-bisphosphate phosphodiesterase in higher plants.

W C McMurray 1, R F Irvine 1
PMCID: PMC1148788  PMID: 2833230

Abstract

A phospholipase C which hydrolyses phosphatidylinositol 4,5-bisphosphate to release inositol trisphosphate was detected in a sedimentable fraction from celery and from some other higher plants. The particulate enzyme also hydrolyses phosphatidylinositol, whereas the soluble phosphatidylinositol phosphodiesterase described previously [Irvine, Letcher & Dawson (1980) Biochem. J. 192, 279-283] acts only on phosphatidylinositol, and we were unable to detect activity of this soluble activity on phosphatidylinositol 4,5-bisphosphate. Activity of the particulate enzyme is markedly enhanced in the presence of deoxycholate, but not of other detergents; the particulate enzyme can also be solubilized by extraction with deoxycholate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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