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. 1983 Dec 1;215(3):705–708. doi: 10.1042/bj2150705

Differences in the rates of aggregation of proteoglycans from human articular cartilage and chondrosarcoma.

M T Bayliss, G D Ridgway, S Y Ali
PMCID: PMC1152456  PMID: 6661192

Abstract

Pieces of adult human articular cartilage and chondrosarcoma were incubated in the presence of [35S]sulphate. After continuous or pulse-change incorporation of radioactivity, proteoglycans were extracted with 4.0 M-guanidinium chloride, purified by equilibrium density-gradient centrifugation and fractionated by gel chromatography. A comparison of the results suggests that the formation of stable aggregates occurs at a lower rate in articular cartilage than in chondrosarcoma.

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Selected References

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