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. 1985 Oct 1;231(1):221–223. doi: 10.1042/bj2310221

Effects of short-term insulin deficiency on lipogenesis and cholesterol synthesis in rat small intestine and liver in vivo.

D H Williamson, V Ilic, J Hughes
PMCID: PMC1152729  PMID: 3904733

Abstract

The rate of lipogenesis in rat intestine increased on oral glucose loading and decreased after induction of acute insulin deficiency with streptozotocin. The latter effects could be partially reversed by administration of insulin. Parallel changes in the rate of lipogenesis were found in liver. In contrast, insulin deficiency did not alter the rate of cholesterol synthesis in intestine, but decreased it in liver. The physiological significance of the regulation of intestinal lipogenesis by insulin is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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