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. 1985 Nov 15;232(1):273–276. doi: 10.1042/bj2320273

Selectivity of the insulin-like actions of vanadate on glucose and protein metabolism in skeletal muscle.

A S Clark, J M Fagan, W E Mitch
PMCID: PMC1152869  PMID: 3910028

Abstract

To determine if vanadate has insulin-like actions in skeletal muscle, we measured its effects on glucose and protein metabolism in epitrochlearis muscles of rats. Compared with insulin, vanadate increased glucose uptake, glycogen synthesis and glycolysis to a lesser degree, but caused a greater stimulation of lactate and glucose oxidation. Unlike insulin, vanadate did not change either protein synthesis or degradation. These different metabolic responses could be related to the different pattern of insulin-receptor phosphorylation caused by insulin and vanadate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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