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. 1980 Jan 15;186(1):279–286. doi: 10.1042/bj1860279

Degradation of [3H]chondroitin 4-sulphate and re-utilization of the [3H]hexosamine component by the isolated perfused rat liver.

A D MacNicholl, F S Wusteman, P J Winterburn, G M Powell, C G Curtis
PMCID: PMC1161528  PMID: 6768355

Abstract

Radiolabelled chondroitin 4-sulphate was isolated after incubation of rat rib cartilage with N-acetyl-D-[6-3H]galactosamine. After proteolytic digestion of the tissue with either papain or trypsin the released [3H]chondroitin 4-sulphate was added to an isolated perfused rat liver system. Analysis of perfusate after several hours perfusion showed that radiolabelled amino sugars were secreted by the liver in a low-molecular-weight form and as components of glycoproteins.

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Selected References

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