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. 1980 May 15;188(2):337–343. doi: 10.1042/bj1880337

Specific inactivation of lysosomal glycosidases in living fibroblasts by the corresponding glycosylmethyl-p-nitrophenyltriazenes.

O P Van Diggelen, H Galjaard, M L Sinnott, P J Smith
PMCID: PMC1161875  PMID: 6772162

Abstract

1. beta-D-Galactopyranosylmethyl-p-nitrophenyltriazene can specificag detectable changes in cell viability or the activities of other hydrolases. 2. beta-D-Glucopyranosylmethyl-p-nitrophenyltriazene behaves similarly towards lysosomal beta-glucosidase, but also inactivates some alpha-glucosidase. 3. Both beta-galactosidase and beta-glucosidase activities in triazene-treated confluent fibroblast cultures recover exponentially; if zero-order enzyme production is assumed, turnover times of 10 and 5 days respectively can be estimated.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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